Clinical trials
Metabolic Syndrome clinical trials
Below are recruiting metabolic syndrome clinical trials, each written for real people, not researchers. We’re tracking 227 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03215836Recruiting
Study obesity and metabolism in adults with asthma
This study looks at how weight and blood-sugar/fat changes in the body may affect the airways in people with asthma. You may be asked to complete breathing tests and possibly an airway procedure (bronchoscopy) to help researchers compare groups.
Aurora, ColoradoAges 18–65 - NCT07707778Enrolling by invitationPhase 4
Tirzepatide for Weight and Aging in People with HIV
This trial tests whether a weight-loss medicine called tirzepatide can slow biological aging and improve metabolism in people with HIV who are already on effective treatment. It may help you reduce weight and possibly reverse some signs of aging.
TaipeiAges 18 years+ - NCT06049420Recruiting
Lifestyle medicine for rural patients with chronic disease
This trial tests whether exercise therapy can help people with two or more chronic conditions like obesity, diabetes, or heart disease. It's designed for rural patients and requires a referral from your doctor.
Lewisburg, West VirginiaAges 18–64 - NCT06394934Recruiting
Home blood pressure changes and artery health in hypertension
This study looks at how changes in home blood pressure readings over time relate to hardening of the arteries and metabolic problems in people with high blood pressure. If you take medication for high blood pressure and monitor your pressure at home, you may help researchers understand these connections better.
SeoulAges 19 years+ - NCT07589322Recruiting
How GLP-1 drugs reshape fat and metabolism
This study compares how a GLP-1 medication (a drug that helps control blood sugar and weight) changes the way your body stores and uses fat. Researchers will use imaging scans to see these changes over time in people with metabolic syndrome—a cluster of health conditions including high blood pressure, high cholesterol, and excess weight.
TaipeiAges 20–65 - NCT06211868Recruiting
Early heart disease risk study for adults 40-70
This study looks at whether changing your immune system, fats, and metabolism can lower your risk of early heart disease. It is for people with an intermediate to high risk score but who have not yet had a heart attack or stroke.
SingaporeAges 40–70 - NCT07336797RecruitingPhase 2
Empagliflozin for weight and metabolism in HIV
This trial tests if empagliflozin, a diabetes medicine, can improve weight and metabolism in people with HIV who take dolutegravir and have a high body mass index (BMI). It may help reduce weight gain linked to HIV treatment.
CairoAges 18–65 - NCT06360302Recruiting
Exercise and insulin resistance in dialysis patients
This study looks at how exercise affects muscle metabolism and insulin resistance in people on dialysis, compared to those with metabolic syndrome and healthy individuals. It aims to find blood markers that could help assess insulin resistance in dialysis patients.
MontpellierAges 40–75 - NCT07686601Enrolling by invitation
Shockwave therapy for belly fat
This study tests whether a sound-wave device (shockwave therapy) applied to your belly can help shrink fat and improve body measurements. It is for adults who have stubborn belly fat and are otherwise healthy.
Shibīn al Kawm, MenofyiaAges 18 years+ - NCT06336070Recruiting
Power training for metabolic health in postmenopausal cancer survivors
This trial compares two types of exercise—muscle power training and metabolic power training—to see which better improves your body's ability to use energy and control heart function. You may qualify if you are a postmenopausal woman who has had breast cancer and is not currently active.
Valencia, ValenciaAges 35–75 - NCT07606872Enrolling by invitation
Testing a diabetes score to guide treatment reversal
This study tests a new scoring system to help people with type 2 diabetes understand their condition better and potentially reverse or improve it. You'll use a digital platform to track blood sugar, answer health questions, and have blood tests to see if the system helps guide your treatment plan.
Manchester, EnglandAges 18 years+ - NCT04371042Recruiting
Study of liver disease and genes in people with fatty liver
This study collects information about metabolic and unexplained (cryptogenic) liver disease and looks at “omics” tests, which are lab tests that measure patterns in blood or tissue to learn what drives the disease. It may help researchers better understand fatty liver and related serious complications, like liver scarring and liver cancer.
Roma, Rome/lazio/italyAges 18 years+ - NCT06144593Recruiting
Carb cutting for people with type 2 diabetes
This study looks at whether cutting carbs on certain days can improve metabolism for people with type 2 diabetes. It may help if you have mild to moderate diabetes and are overweight or obese.
HvidovreAges 35–75 - NCT05903950Recruiting
Air pollution study to help lower blood pressure
This trial tests whether an air-pollution–reduction approach in your home can help lower blood pressure. It focuses on adults with mildly high blood pressure and certain metabolic health markers.
DohaAges 18–60 - NCT04893226Recruiting
Time-restricted eating for postmenopausal metabolic risk
This trial studies whether limiting when you eat each day can improve blood sugar and other health markers in postmenopausal women with prediabetes or metabolic risk factors. It may help your body’s metabolism if your sleep and daily routine can stay fairly consistent.
Lexington, KentuckyAges 45–65 - NCT06765057RecruitingPhase 2/Phase 3
Probiotics for Depression and Metabolic Health
This trial tests whether taking a probiotic supplement can improve both depression symptoms and metabolic health (like waist size, blood sugar, and cholesterol) in people with major depression. It may be a good fit if you are already on an antidepressant and have signs of metabolic syndrome.
Riyadh, Riyadh RegionAges 18–65 - NCT07728669Recruiting
Digital diet app for people on GLP-1 therapy
This study tests a smartphone app that gives dietary advice to people who are overweight or obese and also take a GLP-1 medication (like semaglutide) for weight or diabetes. The app will help you follow a healthy eating plan while using the medication.
AlmatyAges 21–65 - NCT03128996RecruitingPhase 1/Phase 2
Bone marrow transplant with lighter chemo for non-cancer illnesses
This early-phase study tests a safer “lighter” conditioning chemo plan before a bone marrow transplant for people with non-cancer blood and immune disorders. It aims to reduce transplant risk while using donor marrow that does not match perfectly in the HLA type.
New Haven, ConnecticutAges 1 day–21 years - NCT03418857RecruitingPhase 1/Phase 2
Probiotics for weight- and blood-sugar–related gut health
This trial tests whether taking probiotics can improve gut health in people with early metabolic problems related to extra body fat, cholesterol, blood pressure, or blood sugar. It’s a Phase 1/2 study, meaning safety and early effectiveness are being tested.
University Park, PennsylvaniaAges 55–75 - NCT03569735Recruiting
Elderly health survey in Nanshan, Shenzhen
This study follows people age 65 and older in Nanshan to learn about health over time using surveys and health samples. It may help researchers understand what supports healthy aging in the community.
Shenzhen, GuangdongAges 65 years+ - NCT03794531Recruiting
Study of health, stress, and lifestyle changes in Puerto Rico
This study looks at how people’s health, day-to-day stress, and living conditions in Puerto Rico change over time. You might help researchers understand what trends are happening and what could be improved.
San JuanAges 30–75 - NCT04040777Recruiting
Cardiometabolic risk registry for adults
This study is a health registry that collects information about risk factors for heart and metabolic problems in adults. It may help doctors better understand who is at higher risk and guide future prevention strategies.
Pilar, Buenos AiresAges 18 years+ - NCT04407780Recruiting
Cardio-oncology patient registry
This is a registry (a research database) for people who are being followed in cardio-oncology, which means care for heart problems related to cancer or cancer treatments. It may help doctors better understand these conditions and improve future care.
ParisAges 18 years+ - NCT04583514Recruiting
Overfeeding study to see how body fat can expand
This trial studies how your body’s fat tissue changes when you eat extra food for 8 weeks. It may help researchers understand why some people gain more weight than others.
Baton Rouge, LouisianaAges 18–42
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Common questions
- Are there clinical trials for metabolic syndrome?
- Yes. Clin2 currently lists 227 recruiting metabolic syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a metabolic syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a metabolic syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.