Clinical trials
Metabolic Syndrome clinical trials
Below are recruiting metabolic syndrome clinical trials, each written for real people, not researchers. We’re tracking 227 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06523790Recruiting
How different exercises affect your body and metabolism
This study looks at how different types of exercise affect your body functions and metabolism over 8 months. It may help you learn what exercise works best for you.
Zhoukou, HenanAges 18–65 - NCT06939985Recruiting
Heart health and metabolism registry for heart failure
This trial is a registry that will follow people with different types of chronic heart failure to better understand how heart health and metabolism are linked. It may help doctors improve care for future patients.
ShanghaiAges 18 years+ - NCT05806801Recruiting
Study how weight loss changes the body with or without exercise
This study looks at how your metabolism (how your body uses energy and controls blood sugar/fats) changes during weight loss, comparing weight loss alone versus weight loss plus exercise. It may help researchers understand what body changes happen with different approaches and why.
Ann Arbor, MichiganAges 18–40 - NCT05950282Recruiting
Study of insulin sensitivity differences by age and PCOS status
This study looks at how well the body uses insulin (insulin sensitivity) across different ages, sexes, races, body weights, and whether someone has PCOS. It may help researchers understand why insulin function varies and how PCOS could be linked to metabolic health.
Houston, TexasAges 18 years+ - NCT07426172Recruiting
Lactate levels and metabolism in active adults
This trial looks at how high lactate levels (a natural chemical in your body) affect the way your body uses fat and sugar. It is for people with metabolic syndrome who are already physically active.
San Javier, MurciaAges 18–65 - NCT06852365RecruitingPhase 2
Birth control pill and resistant starch for PCOS
This trial tests whether adding a type of fiber (resistant starch) to a common birth control pill can improve health in women with PCOS. It aims to see if this combination helps with weight, hormones, and metabolism.
Philadelphia, PennsylvaniaAges 18–40 - NCT07460856Recruiting
Can Cranberries Improve Your Gut and Metabolic Health?
This study tests if eating cranberries can improve your gut health and metabolism. It’s for people who are overweight and have early signs of metabolic problems, like high blood sugar or high triglycerides.
Québec, QuebecAges 25–70 - NCT06661655Recruiting
Testing a new ultrasound for liver fat in MASLD patients
This study tests a new ultrasound device that uses sound waves to measure fat in the liver without needles or surgery. It is for people with a type of fatty liver disease called MASLD or MASH, who are already getting an MRI to check their liver.
AngersAges 18–80 - NCT05047354Recruiting
Study cholesterol metabolism in rare genetic conditions
This study looks at body chemistry (cholesterol-related lab findings) and physical features in people with Smith-Lemli-Opitz syndrome and related rare genetic cholesterol disorders. It may help researchers better understand these conditions and how they affect the body.
Bethesda, MarylandAges 1 day–100 years - NCT07036952Enrolling by invitation
Omega-3 for metabolic syndrome in PCOS
This trial tests if adding omega-3 supplements to standard care helps women with PCOS who also have metabolic syndrome. It may offer a natural way to improve associated health issues.
Dhaka, BsmmuAges 18–36 - NCT06502834RecruitingPhase 1
Testing a probiotic supplement for overweight people
This trial studies a supplement called D. piger to see if it's safe and how it affects alcohol breakdown in overweight adults with insulin resistance. You would take the supplement daily for 4 weeks.
AmsterdamAges 18–70 - NCT07106879Recruiting
Pre-screening for future metabolic and psychiatric studies
This study does not test a new treatment. It is a pre-screening program to see if you might qualify for future clinical trials on metabolic conditions (like diabetes or weight issues) or psychiatric health (like depression or anxiety). You will be asked some questions and may do some basic health checks to see which future trials could be a good fit for you.
Brooklyn, New YorkAges 18 years+ - NCT07431593Recruiting
Study on inflammation markers in obesity
This trial examines how two blood markers, SII and SIRI, relate to health issues linked to obesity. It aims to help doctors better predict and manage conditions like metabolic problems in overweight and obese adults.
VaraždinAges 18 years+ - NCT07746635Recruiting
Fecal transplant for obese women with polyendocrine metabolic ovarian syndrome
This study tests whether a fecal microbiota transplant (a transfer of healthy gut bacteria) can help women with polyendocrine metabolic ovarian syndrome who are also overweight or obese and planning a frozen embryo transfer. It aims to see if this treatment can improve hormone balance and possibly increase the chance of a successful pregnancy.
Shanghai, Shanghai MunicipalityAges 20–40 - NCT07703683Recruiting
Muscle health in metabolic and hormone diseases
This trial looks at how muscle health is affected by metabolic or hormone disorders, aiming to find better markers for muscle loss called sarcopenia.
Woluwe-Saint-Pierre - Sint-Pieters-WoluweAges 18 years+ - NCT05574153Recruiting
Testing heart oxygen reserve in metabolic syndrome and healthy adults
This study measures how much oxygen your heart can use during stress and at rest using an MRI scan. It compares people with metabolic syndrome (a cluster of health risks) to people without those risks, to understand differences in heart function.
Montreal, QuebecAges 18–80 - NCT05802121RecruitingEarly Phase 1
Testing a gut bacteria supplement side effects during prostate hormone therapy
This early-phase study looks at how changing gut bacteria (especially Akkermansia) affects metabolic side effects in men starting prostate hormone therapy (ADT). It may help researchers understand how to reduce or manage side effects for people on ADT.
London, OntarioAges 18 years+ - NCT06416488Recruiting
HIIT for heart health in school-age kids
This trial tests whether a high-intensity interval training (HIIT) program can improve heart health and reduce risk factors like high blood sugar, cholesterol, and blood pressure in school-age children. It's for children who have at least one of these problems and are not already doing intense exercise.
Shanghai, Shanghai MunicipalityAges 7–18 - NCT06528639Recruiting
Exercise program to reduce heart and metabolic risk
This study tests whether a personalized exercise plan guided by a special breathing test can help lower your risk for heart disease and related conditions. You may qualify if you are not very active and have early signs of metabolic syndrome like a larger waist, higher blood sugar, or higher blood pressure.
Beijing, Beijing MunicipalityAges 30–65 - NCT07540949Recruiting
Lemon Fermented Product for Weight and Metabolism in Adults
This study tests whether a lemon fermented product supplement can help improve metabolism and metabolic health in adults with obesity. Participants will take capsules and have their metabolism and health markers measured over time.
TaoyuanAges 18–65 - NCT06363253Recruiting
Gut bacteria study in obesity and muscle loss
This study looks at the bacteria in your gut (the microbiome) to understand how they relate to obesity and muscle loss. Researchers will collect stool samples to analyze the gut bacteria, which may help find new ways to treat metabolic diseases.
SingaporeAges 21–99 - NCT07269847Recruiting
Beef-heavy diet study for adults with pre-diabetes
This study tests whether a diet rich in beef can improve metabolic health in adults with pre-diabetes or metabolic syndrome compared to a typical healthy U.S. diet. Eligible participants will follow one of two meal plans for several weeks.
Guelph, Ontario - onAges 18–74 - NCT06605898Recruiting
Metabolic and lifestyle study for adults 45-64
This study tests a personalized diet and lifestyle program to improve metabolic health. It may help if you are between 45 and 64, do not smoke, and have no major digestive or liver conditions.
Urbana, IllinoisAges 45–64 - NCT05705804Recruiting
Comparing statins and ezetimibe for heart patients with metabolic syndrome
This trial tests if pitavastatin alone or with ezetimibe affects blood sugar differently than atorvastatin in people who have heart or blood vessel disease and metabolic syndrome but do not have diabetes.
SeoulAges Any age
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Common questions
- Are there clinical trials for metabolic syndrome?
- Yes. Clin2 currently lists 227 recruiting metabolic syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a metabolic syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a metabolic syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.