Clinical trials
Metabolic Syndrome clinical trials
Below are recruiting metabolic syndrome clinical trials, each written for real people, not researchers. We’re tracking 227 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04634591Recruiting
Weight-loss surgery study for people with severe obesity
This trial studies bariatric (weight-loss) surgery and how well it helps people reach and keep a healthier weight. You may qualify if you have severe obesity and have not been able to maintain weight loss with other attempts, and if you can safely follow the study plan.
Bialystok, Podlaskie VoivodeshipAges 18 years+ - NCT04708431Recruiting
Study of health and wellbeing in people with androgen insensitivity
This study looks at the long-term health and wellbeing of people with androgen insensitivity, a genetic condition that affects how the body responds to androgens (male-type hormones). It may help your care team understand what to watch for over time and improve future guidance for patients and families.
Bethesda, MarylandAges 8–99 - NCT05054296RecruitingPhase 2
Exercise and Fitbit monitoring to lower heart risk in prostate cancer
This Phase 2 study tests whether a structured exercise and lifestyle program, tracked with a Fitbit, can reduce cardiovascular (heart) risk in men with prostate cancer on hormone therapy. It also checks whether this is safe and feasible while monitoring symptoms and fitness changes.
Houston, TexasAges 18 years+ - NCT05117424Recruiting
Study of metabolism and plaque changes in heart disease
This trial looks at how treating or managing conditions like diabetes, prediabetes, obesity, kidney disease, or high cholesterol affects artery plaque over time. It may help researchers find ways to slow plaque buildup and related heart risks.
ShanghaiAges 18–80 - NCT05242315RecruitingPhase 4
Long-acting tacrolimus after liver transplant
This trial studies whether taking an extended-release form of tacrolimus (a medicine to prevent transplant rejection) after a liver transplant works well for people who are followed at the University of Alberta. It may help simplify dosing and monitor safety and effectiveness after transplant.
Edmonton, AlbertaAges 18 years+ - NCT05533749Recruiting
E-Health coaching to improve health habits in severe mental illness
This study tests an online (eHealth) program to help people with severe mental illness improve physical health and everyday lifestyle behaviors. If you’re eligible, you’ll be asked to use the internet program and complete questionnaires.
The Hague, South HollandAges 18–65 - NCT05554016Recruiting
Ultra-processed food study in kids with obesity
This study looks at how eating ultra-processed foods affects metabolism and body weight in children and teens with obesity, and compares them with healthy peers. Your participation may help scientists understand whether diet choices contribute to weight and metabolic problems.
NaplesAges 6–18 - NCT05585190Recruiting
Sit-stand desk study for people at diabetes risk
This trial tests whether using a sit-stand desk at work helps people who are overweight and at risk for diabetes. Participants may be asked to change how much they sit during the workday to improve health markers.
Milwaukee, WisconsinAges 18–79 - NCT05623150Recruiting
Biopsy-based study for alcohol and metabolic liver disease
This trial studies people with liver disease linked to alcohol use or metabolic syndrome (a cluster of conditions like weight gain and insulin resistance). It uses recent standard-of-care liver biopsy results to better understand these chronic liver problems and how they relate to cancer risk.
NiceAges 18 years+ - NCT05651724Recruiting
MASH screening study for people with diabetes or obesity
This study screens participants for MASH (a type of liver fat inflammation) using information about your health and risk factors. It may help you and your care team learn whether you could have MASH and need follow-up.
Brussels, Vlaams-brabantAges 18–75 - NCT05651919Recruiting
Blood test study to understand diabetic heart weakness
This study measures immune cells from your blood to find markers (biomarkers) that may explain or predict diabetic cardiomyopathy, a type of heart condition linked to diabetes. You may benefit mainly by being closely monitored and contributing to research that could improve future diagnosis or risk tracking.
BronAges 40–85 - NCT05737342Recruiting
Test supplement to lower A1c and steady blood sugar
This trial studies ANKASCIN 568-P products to see if they can lower A1c (a blood sugar average) and help regulate blood glucose. It may help people with early blood sugar problems, but you must avoid diabetes medicines during the study.
TaipeiAges 20 years+ - NCT05780099Recruiting
Study of patients treated in internal medicine clinics
This observational study follows people receiving care in Internal Medicine at San Raffaele Hospital to better understand what kinds of conditions they have. It does not test a new treatment, but your information may help improve future care.
MilanAges 18 years+ - NCT05845424RecruitingPhase 4
High-intensity cholesterol pills for people with silent calcium
This trial studies whether high-intensity statin plus ezetimibe can improve heart health in people who do not have symptoms but have calcium buildup in their heart arteries. It may help lower cholesterol and reduce future heart risks for the right participants.
SeoulAges 40 years+ - NCT05866107Recruiting
App and smart scale program for weight loss in bipolar or schizophrenia
This study tests whether using a health app and smart body-fat scales helps people who are overweight or obese lose weight. It is designed for adults with bipolar disorder or schizophrenia who are stable and can safely follow the weight-loss and activity plan.
Beijing, Beijing MunicipalityAges 18–60 - NCT05972564RecruitingPhase 1/Phase 2
SGLT2 drug trial for belly fat inflammation before weight-loss surgery
This early-phase trial tests whether an SGLT2 drug can reduce inflammation in belly fat and improve blood vessel function. It may help people with metabolic syndrome prepare for (and potentially benefit around) planned gastric bypass or sleeve surgery.
Nashville, TennesseeAges 18 years+ - NCT06022549Recruiting
Mobile health for HIV patients with metabolic and bone issues
This trial tests a mobile health program designed to help people with HIV manage metabolic syndrome and bone loss. It aims to find if text messages and health tips can improve your health.
TaipeiAges 30 years+ - NCT06099288Recruiting
Strong families start at home: A healthy eating study for Latinx families
This study tests a program to help families eat healthier together at home. It is for Latinx caregivers of young children and involves recording a few meals to see how the program helps.
Providence, Rhode IslandAges 18 years+ - NCT06132477RecruitingPhase 4
Study of GLP-1 medicines after weight loss surgery
This study looks at what happens when people taking a GLP-1 medication (like Ozempic) either stop or continue it after weight loss surgery. The goal is to learn whether staying on the medicine helps with long-term weight control.
Columbia, MissouriAges 18 years+ - NCT06172335Recruiting
Testing fish oil for heart health in people with belly fat
This study tests whether a type of fish oil can help reduce plaque buildup in arteries, focusing on people with high triglycerides and extra belly fat.
OsloAges 20–70 - NCT06226194Recruiting
Genes and weight loss after bariatric surgery
This study looks at how your genes might affect how much weight you lose after gastric sleeve or gastric bypass surgery. You may be able to help doctors better predict weight loss results for future patients.
Lleida, LeidaAges 18–65 - NCT06305195Recruiting
Heart rate and risk in metabolic syndrome
This trial looks at how heart rate variability relates to heart disease risk in people with and without diabetes or pre-diabetes. It may help understand which patients need closer monitoring.
AlexandriaAges 18–70 - NCT06112418Recruiting
Personalized vs standard care to prevent heart attacks
This trial compares two ways to prevent heart attacks and strokes: one uses a special heart CT scan to guide care, the other uses standard risk factors like blood pressure and cholesterol. You may be eligible if you are older (men over 55, women over 65) and have diabetes, prediabetes, or metabolic syndrome.
Chandler, ArizonaAges 55 years+ - NCT06377254Recruiting
How activity or inactivity changes your body
This study looks at how changing your physical activity level (either becoming more or less active) affects your whole body over 6 months. It is for people aged 50–65 who are overweight and either quite sedentary or fairly active, and who are willing to change their routine.
Nottingham, NottsAges 50–65
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Common questions
- Are there clinical trials for metabolic syndrome?
- Yes. Clin2 currently lists 227 recruiting metabolic syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a metabolic syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a metabolic syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.