Clinical trials
Metabolically Healthy Obesity clinical trials
Below are recruiting metabolically healthy obesity clinical trials, each written for real people, not researchers. We’re tracking 65 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07165431Recruiting
Postbiotic supplement study for overweight and obesity
This study tests whether taking a daily postbiotic gummy for 12 weeks can improve body composition and metabolic health in people with overweight or obesity. It may help if you have stable weight and no major health conditions like diabetes.
Pamplona, NavarreAges 18–70 - NCT06226194Recruiting
Genes and weight loss after bariatric surgery
This study looks at how your genes might affect how much weight you lose after gastric sleeve or gastric bypass surgery. You may be able to help doctors better predict weight loss results for future patients.
Lleida, LeidaAges 18–65 - NCT06859853RecruitingPhase 1
MWN109 injection safety study in healthy volunteers
This trial tests an investigational injection called MWN109 to see if it is safe and how the body processes it. It is for healthy adults only, and the results will help decide if the drug should be tested in people with medical conditions.
Melbourne, VictoriaAges 18–50 - NCT05945537RecruitingPhase 1
Testing INI-822 in healthy people and those with MASH
This study tests a new oral medication (INI-822) to see if it’s safe and how the body handles it in healthy volunteers and in people with MASH. MASH is a type of fatty liver disease with inflammation and possible scarring. If you have MASH, the study also checks if the drug can improve markers of liver health. You will need to come to the study site for visits and follow strict guidelines about birth control, alcohol, and other medicines.
Camperdown, New South WalesAges 18–70 - NCT05371496Enrolling by invitationPhase 4
Semaglutide for heart failure patients with preserved pumping function
This Phase 2 trial studies whether semaglutide can improve heart function and related body/heart “metabolic” effects in people with heart failure with preserved ejection fraction. It may help you by improving the heart pressures that build up when you’re active and may reduce harmful strain on the body.
Rochester, MinnesotaAges 18 years+ - NCT06938269RecruitingPhase 1
Study of MWN109 tablets in healthy adults
This trial tests a new tablet called MWN109 in healthy adults to see how safe it is and how the body handles it. It has two parts: one for people with a wide range of body weights, and another specifically for people with higher body weight. The results will help guide future studies.
Adelaide, South AustraliaAges 18–60 - NCT07675590RecruitingPhase 1
Safety study of TIX100 in healthy volunteers
This study tests a new oral medication called TIX100 in healthy people to see if it is safe and how the body handles it. It is the first step in human testing, so it focuses on safety and side effects.
Chula Vista, CaliforniaAges 18–70 - NCT06398340Recruiting
Can a wearable device track what you eat?
This study uses a wearable device (like a smartwatch) to see if it can track what you eat. You would wear the device for a few days and report your meals. It is for generally healthy adults.
LondonAges 18–65 - NCT07395973Recruiting
Ketogenic drink and muscle health in older adults
This study tests whether a special ketogenic drink taken for 4 weeks can improve how your body uses energy and help maintain muscle health. It may be a good option if you are between 60 and 80, overweight but not diabetic, and not very active.
MaastrichtAges 60–80 - NCT03927638Enrolling by invitation
Standing versus sitting study for heart and metabolism measures
This trial compares how different body positions (sitting vs standing) affect blood and heart-related measurements in otherwise healthy adults. It may help researchers understand which position is better for metabolic and cardiovascular health.
Montclair, New JerseyAges 18–50 - NCT05962372Recruiting
Culturally tailored diet program for adults in Puerto Rico
This study tests a diet program designed to fit Puerto Rico culture and daily life. It may help adults with weight or blood sugar or blood fat concerns improve their health through regular check-ins.
San JuanAges 30–65 - NCT06013592Recruiting
Gut hormone and eating behavior meal study
This study looks at how a natural gut hormone called LEAP2 affects appetite and eating behavior. You will eat a fixed meal and have blood samples taken to understand how your body responds.
LondonAges 18–60 - NCT06239116RecruitingPhase 1/Phase 2
RM-718 for obesity from hypothalamus injury or Prader-Willi syndrome
This study tests a new medicine called RM-718 for people with severe obesity linked to a specific brain pathway (MC4R). It may help if your obesity is due to a brain injury or tumor affecting the hypothalamus, or if you have Prader-Willi syndrome.
Birmingham, AlabamaAges 12–65 - NCT06117241Recruiting
Reducing metabolic risk in couples after colon polyp diagnosis
This study tests a program to improve metabolic health in couples where one person had colon polyps. You and your partner may join if you both are overweight or obese, live together, and share meals.
Columbia, South CarolinaAges 9–55 - NCT06575465Recruiting
Boosting health in Bedouin families: community support for metabolic health
This study tests whether family and community-based programs can help Bedouin adults better manage metabolic conditions like overweight, prediabetes, or type 2 diabetes. It aims to find practical ways to improve treatment adherence and overall health.
RahatAges 18 years+ - NCT06345937Recruiting
Heart health lifestyle program for women with multiple risks
This study tests whether a weekly, 24-week lifestyle program at the University of Toronto can improve heart health in women who have several risk factors like being inactive, having a BMI of 25 or higher, and additional issues like high waist circumference or conditions like high blood pressure or pre-diabetes.
Toronto, OntarioAges 30 years+ - NCT07422220Recruiting
Walnuts and brain health: a long-term study
This study tests whether eating walnuts every day for a long time can help keep your brain healthy as you age. It is for middle-aged and older adults who carry extra weight around their belly but are otherwise generally healthy.
Maastricht, LimburgAges 45–75
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Common questions
- Are there clinical trials for metabolically healthy obesity?
- Yes. Clin2 currently lists 65 recruiting metabolically healthy obesity studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a metabolically healthy obesity trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a metabolically healthy obesity trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.