Clinical trials
Microbiome clinical trials
Below are recruiting microbiome clinical trials, each written for real people, not researchers. We’re tracking 346 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06805994RecruitingPhase 1
Restoring infant nose bacteria after staph treatment
This study tests whether giving a nasal spray of healthy bacteria to infants can restore good germs in the nose after they receive mupirocin ointment to treat Staph aureus. It aims to bring back a healthy nasal microbiome.
Baltimore, MarylandAges birth–60 years - NCT06800833Recruiting
Mango or cookie study for gut, mental, sexual, and skin health
This study is testing whether eating mangoes or low-fat cookies every day for 4 weeks can improve your gut health, and in turn affect your mood, sex life, and skin. If you are generally healthy, not pregnant, and not taking certain medications or supplements, you may be able to join.
San Diego, CaliforniaAges 18–50 - NCT06802276Recruiting
Smart underwear measures gas from diet
This study tests special underwear that can measure gas produced by digestion after eating different foods. Researchers want to see if the underwear can track how diet affects gas production.
Aurora, ColoradoAges 18 years+ - NCT06799481Recruiting
Home-based exercise to help brain tumor survivors with thinking and memory
This study tests whether a virtual home-based exercise program can improve thinking and memory problems caused by brain tumor treatment in teens and young adults. It also looks at how exercise affects gut health.
Atlanta, GeorgiaAges 15–39 - NCT06799351RecruitingPhase 2/Phase 3
Gut bacteria and nerve pain after chemo
This study looks at how bacteria in your gut (microbiome) might be linked to nerve pain from chemotherapy. It is for people who are already in the OzoParQT trial and will provide a stool sample to help understand this connection.
Las Palmas, Las PalmasAges 18 years+ - NCT06746077Enrolling by invitation
Lung disease study in children: new ways to understand infections
This study explores how the immune system and lung microbes affect children with lung disease. It uses extra fluid collected during a standard lung exam to look for new treatment targets.
Aarhus NAges birth–17 years - NCT06595160Recruiting
Diet and gut bacteria in pancreatic cancer treatment
This study looks at how diet and the bacteria in your gut might affect how well chemotherapy works for pancreatic cancer that can be surgically removed. If you have been newly diagnosed with this type of pancreatic cancer, you may be able to join.
Atlanta, GeorgiaAges 18 years+ - NCT06735599Recruiting
Wild blueberries for blood pressure health
This study tests whether eating wild blueberries can improve your gut, brain, and heart health if you have high blood pressure. You'll eat blueberries daily for several weeks and have checkups to see how your body responds.
Atlanta, GeorgiaAges 45–65 - NCT06662747Recruiting
Vaginal microbiome study for African women
This study is looking at the bacteria living in the vagina to understand what makes a healthy microbiome in African women. You will provide self-collected swabs and attend visits to help researchers learn more about vaginal health.
Kisumu, Kisumu CountyAges 18–40 - NCT06709651Recruiting
Gut bacteria treatment for triple-negative breast cancer
This trial tests whether a treatment that targets your gut bacteria (microbiome) can help fight triple-negative breast cancer before surgery. It is for people with newly diagnosed, untreated triple-negative breast cancer that has not spread far.
Cork, MunsterAges 18 years+ - NCT06114784Recruiting
Study of microbiome and severe pneumonia with breathing support
This study looks at how bacteria in your body (microbiome) affect how sick you get from severe pneumonia. It may help doctors find better ways to treat people with serious lung infections who need breathing support.
Hangzhou, ZhejiangAges 18 years+ - NCT06691100Recruiting
How one workout changes gut bugs in women
This study looks at how a single workout changes the bacteria in your gut. It compares women who are very fit with women who don't exercise much, and includes women with different body types.
Washington D.C., District of ColumbiaAges 21–40 - NCT06124833Recruiting
Gut and mouth microbiome study for Korean IBD patients and their family
This study looks at the bacteria in your gut and mouth to understand more about inflammatory bowel disease (IBD). It compares patients with their close family members who do not have IBD to see what might be different.
SeoulAges 13–85 - NCT06678516Recruiting
Does intermittent fasting change your blood microbiome?
This study tests if intermittent fasting (going without food for periods) affects the microorganisms in your blood. It may help researchers understand how fasting influences health.
Lanzhou, GansuAges 18–65 - NCT06681246Recruiting
How gut bacteria affect weight regain after weight loss
This study looks at how the natural bacteria in your gut (the microbiome) might be linked to regaining weight after losing it. It tests whether a short course of antibiotics or a placebo (a sugar pill) affects this process. The goal is to find new ways to help people keep weight off long-term.
RehovotAges 18–65 - NCT06665490Enrolling by invitation
Skin care wash study for mycosis fungoides
This study tests whether a special skin care body wash can improve skin lesions in people with mycosis fungoides, a type of skin lymphoma. Researchers will look at skin bacteria before and after using the wash.
Chicago, IllinoisAges 18–89 - NCT06646185Recruiting
Improving menstrual and vaginal health for women
This study looks at menstrual and vaginal health in women aged 18 to 35. It aims to understand normal cycles and find ways to improve health for all.
Yaoundé, YaoundéAges 18–35 - NCT06639126Enrolling by invitation
Thyme extract for functional gut issues
This trial tests whether a wild thyme extract can help with functional gastrointestinal disorders (common digestive problems without a clear cause). It focuses on the extract's anti-inflammatory and metabolism-related effects.
Granada, GranadaAges 18–75 - NCT06606119Recruiting
Brain, bone marrow, and gut study after major injury
This study is looking at how the brain, bone marrow, and gut interact after a severe injury. It may help doctors understand how to better treat trauma patients.
Gainesville, FloridaAges 18–100 - NCT06603519Enrolling by invitation
Can a diet reduce inflammation after a colonoscopy?
This study tests whether a special diet can help reduce inflammation and improve gut health after a colonoscopy. It is for people who are getting a repeat colonoscopy because they've had polyps before.
San Diego, CaliforniaAges 18 years+ - NCT06602934Recruiting
Pneumonia, heart health, and your body's germs
This study looks at how pneumonia affects the long-term health of your heart and lungs by studying the germs that live in your body. It may help doctors understand why some people get worse and how to better protect your heart after a serious infection.
AngersAges 18–80 - NCT06607523Recruiting
Prebiotic treatment for brain injury recovery
This study tests whether a prebiotic (a type of fiber that feeds healthy gut bacteria) can improve recovery from a brain injury by helping the connection between the gut and the brain. Participants include people with a recent brain injury and their family members or staff, all of whom are part of the Moody Neurorehabilitation Institute community.
Galveston, TexasAges 18 years+ - NCT06310239Recruiting
Microbiome Study for Adults Having Surgery
This study looks at how your body’s natural bacteria (called the microbiome) may change after surgery. Researchers want to learn about the gut and skin bacteria of adults who are having a procedure, which could help improve recovery in the future.
Bethesda, MarylandAges 18–75 - NCT06569368RecruitingPhase 2
Metronidazole with rectal cancer treatment
This trial tests adding the antibiotic metronidazole to standard pre-surgery therapy for locally advanced rectal cancer. The goal is to see if changing the bacteria in your gut can make the cancer treatment work better.
Houston, TexasAges 18 years+
Hear when a new Microbiome trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for microbiome?
- Yes. Clin2 currently lists 346 recruiting microbiome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a microbiome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a microbiome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.