Clinical trials
Microbiome clinical trials
Below are recruiting microbiome clinical trials, each written for real people, not researchers. We’re tracking 350 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06202183Recruiting
Home exercise for gut health in young colorectal cancer patients
This study tests whether a home-based exercise program can improve the health of your gut bacteria during chemotherapy for young-onset colorectal cancer. It aims to help you feel better and potentially improve how well your treatment works.
Boston, MassachusettsAges 18–50 - NCT06262035Recruiting
Gum and implant disease tissue profile study
This study looks at the genetic and bacterial profiles in gum disease and implant infections. It might help find new ways to diagnose or treat these conditions.
StockholmAges 18 years+ - NCT06283355RecruitingPhase 1
Comparing one vs. multiple nasal treatments in NICU babies
This study tests whether giving one versus multiple doses of a special nasal treatment (called nasal microbiota therapy, or NMT) changes the types of helpful bacteria in your baby's nose. The goal is to see if the treatment keeps bad bacteria, like staph, from growing.
Baltimore, MarylandAges birth–60 years - NCT06318507Recruiting
Gut Bacteria and Immunotherapy for Triple-Negative Breast Cancer
This study looks at how bacteria in your gut might affect the way your body responds to immunotherapy for triple-negative breast cancer. It focuses on women who are overweight or obese and are about to start treatment with pembrolizumab before surgery.
Baton Rouge, LouisianaAges 18 years+ - NCT06319755Recruiting
Gut bacteria after Whipple surgery
This study looks at gut bacteria in people who had Whipple surgery for pancreatic cancer and in healthy volunteers. It aims to understand how the microbiome changes after surgery.
Camperdown, New South WalesAges 18 years+ - NCT06329544Recruiting
Study of a high-fructose diet and gut health
This trial tests how a high-fructose diet affects your gut bacteria and overall metabolic health. It is for people who already know they don't absorb fructose well (fructose malabsorbers) and want to understand how this sugar impacts their body.
New York, New YorkAges 25–45 - NCT06331988Recruiting
Study of colon cancer, bacteria, and the immune system
This study looks at how bacteria in your gut, your immune system, and colon cancer interact. It aims to understand these connections to improve future treatments.
MilanAges 18–75 - NCT06342752Recruiting
Breath test for early lung disease in premature babies
This trial studies a breath test to predict lung disease in very premature babies. It could help doctors start treatment earlier to prevent serious breathing problems.
Edegem, AntwerpAges birth–3 days - NCT06349590RecruitingPhase 1/Phase 2
Diet before colon cancer surgery to reduce recurrence
This trial tests whether a specific diet before colon cancer surgery can change the bacteria in your gut to help prevent the cancer from coming back or spreading. Patients who are eligible will follow the diet for a short time before their operation.
Chicago, IllinoisAges 18 years+ - NCT06359808Recruiting
Sleep Problems in Ulcerative Colitis Patients
This study looks at sleep problems in people with ulcerative colitis (a type of inflammatory bowel disease). It aims to understand how sleep affects your condition and may help find better ways to manage both.
Xi'an, ShaanxiAges 18–65 - NCT06382857Recruiting
Testing a special food for malnutrition recovery in children
This trial tests if a special food made from chickpeas, soy, banana, and peanut can help children with moderate or severe malnutrition recover fully and stay healthy. It is for children who do not need hospital care and can eat the food safely.
MaradiAges 6 months–1.9 years - NCT06423976Recruiting
Studying microbes in prostate cancer tumors
This trial collects tumor samples from men with prostate cancer to study the bacteria and other microbes inside the tumor. It aims to learn how these microbes might affect the cancer and treatment.
Sutton, SurreyAges 18 years+ - NCT06448546Recruiting
Gut bacteria in Huntington's disease
This study looks at how gut bacteria are different in people with Huntington's disease who have unusual weight changes. You'll provide stool and blood samples to help researchers understand gut health in HD.
Orlando, FloridaAges 18 years+ - NCT06452992Recruiting
Gut bacteria and sleep apnea in children
This study looks at the bacteria and natural chemicals in children’s bodies to learn more about sleep apnea. It could help doctors understand why some children have sleep problems and find better ways to treat them.
Hong KongAges 6–11 - NCT06453720Recruiting
Predicting Crohn's treatment success with gut bacteria
This study analyzes your gut bacteria to see if it can predict how well you will respond to Crohn's disease treatments. If you are having a colonoscopy for routine care, you may be eligible.
Vancouver, British ColumbiaAges 19–80 - NCT06464952Recruiting
Prebiotics for PTSD and cirrhosis
This trial tests if a prebiotic supplement can improve gut health and PTSD symptoms in people with cirrhosis and PTSD. It aims to see if changing the gut microbiome can help both conditions.
Richmond, VirginiaAges 18 years+ - NCT06492200Recruiting
High-Fiber Diet for Rheumatoid Arthritis
This study tests whether eating more high-fiber foods can improve rheumatoid arthritis symptoms by changing the bacteria in your gut. You would follow a special diet and have your disease activity monitored.
WürzburgAges 18–99 - NCT06495190Recruiting
Blueberries, exercise, and memory in older adults
This study tests whether eating blueberries and doing regular exercise can help with mild memory decline. You will be assigned to one of four groups (blueberries + walking, blueberries + stretching, or similar combos) for 12 weeks.
Kannapolis, North CarolinaAges 65–85 - NCT06505330Recruiting
Probiotics for kids with cleft palate
This study looks at whether giving probiotics (helpful bacteria) to children with cleft palate can improve the bacteria in their airways and possibly prevent infections. Researchers want to see if this simple treatment helps keep kids healthier.
Edegem, AntwerpAges 6 months–2 years - NCT06508502Recruiting
Pancreatitis Severity and Gut Bacteria Study
This study looks at how the bacteria in your gut (microbiome) might affect the severity of a first-time acute pancreatitis attack. It aims to see if certain gut bacteria can predict how serious the illness will be, which could help doctors treat patients better.
Göttingen, Lower SaxonyAges 18 years+ - NCT06519162Recruiting
Liver-gut link study for liver disease patients and their families
This study looks at how gut bacteria differ in people with specific liver diseases and their household contacts. It may help researchers understand the connection between the liver and gut.
Daejeon, Jung-guAges 19 years+ - NCT06526689Recruiting
Lung health and germs in people exposed to TB
This study looks at how the immune system and natural germs in the lungs work in people who have recently been in close contact with someone with active tuberculosis (TB). It aims to better understand how the body responds to TB exposure.
Oxford, OxfordshireAges 18–65 - NCT06536881Recruiting
Diet and gut health during breast cancer chemo
This study looks at how changing your diet during chemotherapy affects side effects and your body's energy use. It involves providing stool samples to study gut bacteria.
Washington D.C., District of ColumbiaAges 18 years+ - NCT06545123Recruiting
How different exercises affect gut health in older adults with muscle loss
This study looks at how different types of exercise can change the bacteria in your gut for older adults who have muscle loss (sarcopenia). You will be assigned to one of two exercise programs to see which one helps your muscles and gut health the most.
PortoAges 60 years+
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Common questions
- Are there clinical trials for microbiome?
- Yes. Clin2 currently lists 350 recruiting microbiome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a microbiome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a microbiome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.