Clinical trials
Microbiome clinical trials
Below are recruiting microbiome clinical trials, each written for real people, not researchers. We’re tracking 346 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03507673Recruiting
Study of vaginal and uterine microbiome after frozen embryo transfer
This study looks at how bacteria in the vagina and lining of the uterus change during the “luteal phase” (the time after ovulation and before a pregnancy test) in people using frozen embryo transfers. It may help researchers understand what conditions support embryo implantation and pregnancy in assisted reproduction.
Saarbrücken, SaarlandAges 18–45 - NCT07069751Recruiting
Plant-based diet study for smoldering myeloma
This study tests whether a high-fiber plant-based diet can improve gut health in people with smoldering multiple myeloma. It aims to see if diet changes can slow or prevent the disease from progressing.
Milan, MilanoAges 18–75 - NCT06986265Recruiting
Kidney failure, weight loss, and gut health study
This study looks at how gut bacteria might affect weight loss in people with kidney failure who are on dialysis. It may help find new ways to prevent or treat weight loss in this condition.
BrusselsAges 18 years+ - NCT06048614Recruiting
Saline enema for meconium blockage in premature babies
This trial tests if giving a saline enema helps premature babies with meconium blockage pass stool, start feeding, and improve gut and brain health. It may reduce complications and help babies grow better.
SingaporeAges 1 day–8 months - NCT07051902Recruiting
Microbiome and Atopy in Mali
This study is looking at how the natural bacteria on our skin and in our gut relate to eczema and asthma in people living in Mali. It will compare people with these conditions to healthy volunteers to learn more about what might cause them.
BamakoAges 3 years+ - NCT07052071Recruiting
TAVI's effect on gut bacteria in aortic stenosis
This study looks at how a heart valve procedure called TAVI affects the bacteria in your gut. It may help doctors understand how the procedure impacts your overall health.
AthensAges Any age - NCT07052409Enrolling by invitation
Protecting HIV-exposed infants from severe infections
This trial studies ways to protect babies who were exposed to HIV before birth but are not infected themselves. It aims to find better interventions to prevent severe infections in these infants.
JohannesburgAges 6 months–45 years - NCT07042438RecruitingPhase 2
Fecal transplant to improve CAR T therapy for lymphoma
This study tests whether a fecal transplant (transferring healthy gut bacteria) can improve outcomes for people with certain lymphomas who have taken strong antibiotics and are about to get CAR T-cell therapy (Yescarta). The goal is to see if rebuilding gut bacteria helps the treatment work better.
Duarte, CaliforniaAges 18 years+ - NCT04691284Recruiting
Test how the gut microbiome changes during major cancer treatment
This study looks at your gut “microbiome” (the bacteria in your intestines) while you receive high-dose chemotherapy and a stem cell transplant, or CAR-T cell therapy. Researchers hope to understand how these treatments affect the microbiome, which may relate to how well patients do.
Bratislava, SlovakiaAges 18 years+ - NCT07025044Recruiting
Bladder microbiome study for women with overactive bladder getting Botox
This study looks at the bacteria in the bladders of women with overactive bladder who are getting Botox injections. It aims to understand how these bacteria might affect treatment results.
Washington D.C., District of ColumbiaAges 55 years+ - NCT07017946RecruitingPhase 1/Phase 2
Gut bacteria transplant for fast-progressing ALS
This trial tests whether a transplant of healthy gut bacteria (called a microbiome transplant) can slow down ALS in people whose disease is progressing rapidly. It aims to see if changing the gut environment can help with symptoms and quality of life.
Durham, North CarolinaAges 18 years+ - NCT06977113Recruiting
High-fiber fermented foods for breastfeeding moms and babies
This study tests if a diet rich in high-fiber fermented foods for breastfeeding mothers can improve the gut health of their exclusively breastfed infants. It is designed for healthy mothers and babies without chronic conditions or recent antibiotic use.
Glasgow, ScotlandAges 2 months–45 years - NCT06951477Recruiting
Gut health and knee replacement revision study
This study looks at how the bacteria in your gut might affect recovery after a second knee replacement surgery. Researchers want to learn more about the connection between gut health and surgical outcomes.
London, OntarioAges Any age - NCT06941090Recruiting
Stool sample collection for nutrition gut health study
This study asks participants of the NutriNet-Santé health study to provide a stool sample. Researchers want to understand how diet and gut bacteria affect health.
BobignyAges 18 years+ - NCT06448546Recruiting
Gut bacteria in Huntington's disease
This study looks at how gut bacteria are different in people with Huntington's disease who have unusual weight changes. You'll provide stool and blood samples to help researchers understand gut health in HD.
Orlando, FloridaAges 18 years+ - NCT06926166Recruiting
Genes and germs in early life study
This study looks at how genes and tiny organisms in your body (microbiota) affect early childhood development. It involves storing blood and stool samples from you and your child to help researchers learn more.
GuangzhouAges Any age - NCT04611217Recruiting
Testing fiber to change gut bacteria and help with fullness
This study tests how eating different amounts of dietary fiber affects your gut bacteria and how full you feel. You may be able to help researchers understand whether fiber can support appetite and metabolic health.
Columbia, MissouriAges 20–55 - NCT06916481Recruiting
Pneumonia subtypes based on lung bacteria
This study looks at the germs in your lungs to understand why some people's pneumonia doesn't get better with standard antibiotics. If you are hospitalized with pneumonia and have just started treatment, you may be asked to provide a sputum sample so researchers can study your lung microbiome.
ClichyAges 18 years+ - NCT06869941Recruiting
How gut health and fat tissue are linked in the brain
This study looks at how the bacteria in your gut might affect your fat tissue and brain. You may be able to join if you are scheduled to have surgery to remove fat tissue and are willing to sign a consent form.
Girona, GironaAges 20 years+ - NCT06845527Recruiting
Gut bacteria testing in a clinic study
This study looks at people who visit a special gut bacteria clinic. It aims to learn more about their health by testing their gut bacteria as part of regular care.
Rome, RMAges 18 years+ - NCT06846138Enrolling by invitation
Herbal supplement to help metformin work better and cause fewer side effects
This study tests a special herbal blend added to metformin to see if it helps reduce stomach problems and improves blood sugar control in people with type 2 diabetes. Researchers want to understand how the herbs affect the bacteria in your gut.
RigaAges 25–80 - NCT06827977RecruitingPhase 2
Microbiome transplant for constipation and bloating in scleroderma
This study tests a microbiome transplant (friendly bacteria given as an enema or in capsules) to see if it helps with constipation and bloating in people with scleroderma. The goal is to improve digestive symptoms related to your condition.
Houston, TexasAges 18 years+ - NCT06833593Recruiting
Antibiotic combinations for enterococcus blood infection
This study looks at whether using two or more antibiotics together works better than one alone for a specific type of blood infection caused by Enterococcus faecalis bacteria. The goal is to find the safest and most effective way to treat this infection and improve outcomes for patients.
Bologna, BolognaAges 18 years+ - NCT06508502Recruiting
Pancreatitis Severity and Gut Bacteria Study
This study looks at how the bacteria in your gut (microbiome) might affect the severity of a first-time acute pancreatitis attack. It aims to see if certain gut bacteria can predict how serious the illness will be, which could help doctors treat patients better.
Göttingen, Lower SaxonyAges 18 years+
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Common questions
- Are there clinical trials for microbiome?
- Yes. Clin2 currently lists 346 recruiting microbiome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a microbiome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a microbiome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.