Clinical trials
Microbiome clinical trials
Below are recruiting microbiome clinical trials, each written for real people, not researchers. We’re tracking 350 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06805994RecruitingPhase 1
Restoring infant nose bacteria after staph treatment
This study tests whether giving a nasal spray of healthy bacteria to infants can restore good germs in the nose after they receive mupirocin ointment to treat Staph aureus. It aims to bring back a healthy nasal microbiome.
Baltimore, MarylandAges birth–60 years - NCT06813521Recruiting
Antidandruff lotion study for scalp microbiome rebalance
This study tests a new antidandruff lotion designed to restore the natural balance of microbes on your scalp. If you have moderate to severe dandruff and are generally healthy, this trial may help improve your dandruff with a specially formulated product.
LisbonAges 18–60 - NCT06831539RecruitingPhase 1
How bowel prep affects gut bacteria recovery
This study looks at how the bowel preparation medicine (PEG) used before a colonoscopy affects the bacteria living in your gut and how well they recover afterward. Healthy volunteers will take the bowel prep and provide stool samples to help researchers understand this process.
Montreal, QuebecAges 18–70 - NCT06837272Recruiting
Gut health and brain health in Alzheimer's disease
This study looks at how the bacteria in your gut might be connected to memory and thinking problems in Alzheimer's disease. It may help us understand if changes in the gut can affect brain health.
Jining, ShandongAges 60–80 - NCT06869941Recruiting
How gut health and fat tissue are linked in the brain
This study looks at how the bacteria in your gut might affect your fat tissue and brain. You may be able to join if you are scheduled to have surgery to remove fat tissue and are willing to sign a consent form.
Girona, GironaAges 20 years+ - NCT06870981Recruiting
Optimizing nutrition and milk in infants (Opti-NuM)
This study looks at stored information and samples from babies who were part of earlier MaxiMoM nutrition trials. It aims to learn more about how nutrition and milk feeding affect infant health.
Palo Alto, CaliforniaAges 1 hour–3 weeks - NCT06885255Recruiting
Fasting and Exercise for Metabolic Syndrome
This study tests whether combining intermittent fasting with exercise can lower inflammation and improve your metabolism and gut health in people with metabolic syndrome.
Erlangen, BavariaAges 18–80 - NCT06908889Recruiting
Skin bacteria and fungi in light spots on the face
This study looks at the bacteria and fungi living on the skin of people who have light-colored spots (hypopigmentation) on their face. It aims to understand what's different about the skin microbiome in these spots, which may help improve treatment in the future.
Nice, Alpes-MaritimesAges 18 years+ - NCT06916481Recruiting
Pneumonia subtypes based on lung bacteria
This study looks at the germs in your lungs to understand why some people's pneumonia doesn't get better with standard antibiotics. If you are hospitalized with pneumonia and have just started treatment, you may be asked to provide a sputum sample so researchers can study your lung microbiome.
ClichyAges 18 years+ - NCT06921746Recruiting
Urinary microbiome and metabolism changes in overactive bladder treatment
This study looks at how the bacteria and chemicals in your urine change when women receive treatment for overactive bladder. It may help researchers understand why some treatments work better for some people.
Ostrava, Moravian-Silesian RegionAges 18 years+ - NCT06926166Recruiting
Genes and germs in early life study
This study looks at how genes and tiny organisms in your body (microbiota) affect early childhood development. It involves storing blood and stool samples from you and your child to help researchers learn more.
GuangzhouAges Any age - NCT06929364Recruiting
Probiotics for endometriosis – a crossover trial
This study tests whether taking a probiotic supplement can help with endometriosis symptoms. It's for women 35 or younger with moderate to severe endometriosis, and involves a crossover design where everyone gets both the probiotic and a placebo at different times.
ZagrebAges Up to 35 years - NCT06944002Recruiting
Milk and your blood bacteria in healthy adults
This study looks at how drinking milk affects the bacteria in your blood. Healthy volunteers are needed to participate.
RotterdamAges 18–65 - NCT06959043Recruiting
Diet and exercise for type 2 diabetes
This study tests if a plant-based diet and exercise program can improve blood sugar control in people with type 2 diabetes. Participants will live in a hospital for 4 weeks to follow the program closely.
São Paulo, São PauloAges 45–70 - NCT06977113Recruiting
High-fiber fermented foods for breastfeeding moms and babies
This study tests if a diet rich in high-fiber fermented foods for breastfeeding mothers can improve the gut health of their exclusively breastfed infants. It is designed for healthy mothers and babies without chronic conditions or recent antibiotic use.
Glasgow, ScotlandAges 2 months–45 years - NCT06986265Recruiting
Kidney failure, weight loss, and gut health study
This study looks at how gut bacteria might affect weight loss in people with kidney failure who are on dialysis. It may help find new ways to prevent or treat weight loss in this condition.
BrusselsAges 18 years+ - NCT07017946RecruitingPhase 1/Phase 2
Gut bacteria transplant for fast-progressing ALS
This trial tests whether a transplant of healthy gut bacteria (called a microbiome transplant) can slow down ALS in people whose disease is progressing rapidly. It aims to see if changing the gut environment can help with symptoms and quality of life.
Durham, North CarolinaAges 18 years+ - NCT07025044Recruiting
Bladder microbiome study for women with overactive bladder getting Botox
This study looks at the bacteria in the bladders of women with overactive bladder who are getting Botox injections. It aims to understand how these bacteria might affect treatment results.
Washington D.C., District of ColumbiaAges 55 years+ - NCT07042438RecruitingPhase 2
Fecal transplant to improve CAR T therapy for lymphoma
This study tests whether a fecal transplant (transferring healthy gut bacteria) can improve outcomes for people with certain lymphomas who have taken strong antibiotics and are about to get CAR T-cell therapy (Yescarta). The goal is to see if rebuilding gut bacteria helps the treatment work better.
Duarte, CaliforniaAges 18 years+ - NCT07051902Recruiting
Microbiome and Atopy in Mali
This study is looking at how the natural bacteria on our skin and in our gut relate to eczema and asthma in people living in Mali. It will compare people with these conditions to healthy volunteers to learn more about what might cause them.
BamakoAges 3 years+ - NCT07052071Recruiting
TAVI's effect on gut bacteria in aortic stenosis
This study looks at how a heart valve procedure called TAVI affects the bacteria in your gut. It may help doctors understand how the procedure impacts your overall health.
AthensAges Any age - NCT07069751Recruiting
Plant-based diet study for smoldering myeloma
This study tests whether a high-fiber plant-based diet can improve gut health in people with smoldering multiple myeloma. It aims to see if diet changes can slow or prevent the disease from progressing.
Milan, MilanoAges 18–75 - NCT07093346Recruiting
Pectin supplement for fatty liver disease
This study tests whether a pectin supplement (a fiber found in fruits) can reduce inflammation and improve liver and metabolic health in people with fatty liver disease (MASLD). You might be eligible if you have MASLD, a healthy weight range, and can avoid certain medications and foods.
NottinghamAges 18 years+ - NCT07129174Recruiting
Lung bacteria changes in neurosurgery ICU patients with breathing tubes
This study looks at how tiny organisms in the lungs (the lung microbiome) change in neurosurgery patients who need a breathing tube in the ICU. It aims to see if these changes affect recovery or outcomes.
Beijing, Beijing MunicipalityAges 18 years+
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Common questions
- Are there clinical trials for microbiome?
- Yes. Clin2 currently lists 350 recruiting microbiome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a microbiome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a microbiome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.