Clinical trials
Musculoskeletal Diseases or Conditions clinical trials
Below are recruiting musculoskeletal diseases or conditions clinical trials, each written for real people, not researchers. We’re tracking 4,063 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05386173Recruiting
Tests fetal aortic valve balloon surgery for severe narrowing
This trial studies whether doing a procedure before birth to open a baby’s aortic valve improves outcomes. It compares this approach in a specific group of pregnancies with severe heart flow problems seen on ultrasound.
San Francisco, CaliforniaAges 5 months–7 months - NCT05388149RecruitingPhase 2
Neratinib plus Kadcyla to treat leftover HER2 breast cancer
This trial studies whether adding neratinib to Kadcyla (T-DM1) can help eliminate “molecular residual disease,” meaning tiny traces of cancer left after surgery and standard HER2 treatment. It’s for adults with HER2-positive breast cancer who still test positive after a short course of Kadcyla, with no signs of cancer returning or spreading on scans.
Toronto, OntarioAges 18 years+ - NCT05389787Recruiting
Brain stimulation to improve thinking in schizophrenia
This pilot study tests whether stimulating the cerebellum (a part of the brain) using TMS can improve brain function and thinking in people with schizophrenia. If you qualify, you may receive TMS and undergo brain/cognitive assessments to see whether it helps.
New York, New YorkAges 18–60 - NCT05395715Recruiting
Nerve stimulation study for cubital tunnel nerve compression
This study tests whether a specific type of electrical nerve stimulation (conditioning electrical stimulation) can improve outcomes for people with cubital tunnel syndrome. It is mainly for adults with more severe nerve damage based on specialist test results, and who have not had prior surgery for this problem.
Edmonton, AlbertaAges 18–79 - NCT05410275RecruitingPhase 3
Low-dose rivaroxaban for dialysis patients without blood thinners
This study tests whether a lower dose of the blood thinner rivaroxaban is safe for people with kidney failure on dialysis who do not already need blood thinners. The goal is to find a way to prevent blood clots and strokes with less risk of bleeding.
ToursAges 18 years+ - NCT05413850RecruitingPhase 1/Phase 2
Lu-177 PSMA drug study for advanced prostate cancer
This early-stage study tests a radioactive prostate cancer medicine that targets PSMA (a protein on prostate cancer cells). It aims to see how well the treatment works and how safe it is for men whose cancer has spread and shows PSMA on a scan.
Miami, FloridaAges 18 years+ - NCT05414045Recruiting
Transplanting your own frozen testicle tissue for future fertility
This trial studies transplanting frozen testicular tissue back into the body to help restore fertility later. It is meant for people who preserved testicular tissue as children before cancer or a blood disorder treatment.
BrusselsAges 18–50 - NCT05417568Recruiting
Testing how oxalate responses differ in kidney stone patients
This study looks at how the body reacts to oxalate in people with calcium oxalate kidney stones and in people without kidney stones. It may help researchers understand why some people form stones and how to better prevent them.
Birmingham, AlabamaAges 18–60 - NCT05423860Recruiting
HALO prostate study for men with early prostate cancer
This trial studies HALO, a new “human analytics” approach, in men with early-stage prostate cancer. It may help doctors better assess or guide care using MRI and biopsy findings, before or around initial treatment.
Indian Wells, CaliforniaAges 45–90 - NCT05426252RecruitingPhase 1/Phase 2
Lower-toxicity bone marrow conditioning for high-risk thalassemia
This trial tests a modified, lower-toxicity preparation (conditioning) before a bone marrow transplant in children and teens with high-risk thalassemia. It aims to reduce treatment side effects while still allowing transplant success for people who need a donor.
Toronto, OntarioAges 1–18 - NCT05427084RecruitingPhase 2/Phase 3
Canagliflozin to reduce inflammation in heart artery disease
This trial tests canagliflozin to see if it lowers “vascular inflammation” in people with diabetes and stable coronary artery disease. It may help reduce harmful inflammation signals that can raise future heart risk.
Ottawa, OntarioAges 18 years+ - NCT05427370Recruiting
Compare bypass or stent treatment in weak heart patients
This study compares two ways to restore blood flow to the heart—bypass surgery (CABG) or stent procedure (PCI)—in people with a weak pumping heart. It looks at which approach works best when the heart muscle is not pumping well and there are multiple blocked heart arteries.
Los Angeles, CaliforniaAges 18 years+ - NCT05432635RecruitingPhase 1
CAR T-cell and vaccine treatment after stem cell transplant
This Phase 1 study tests a customized immune-cell treatment (CAR T-cells) plus a vaccine given after stem cell transplant for certain aggressive B-cell non-Hodgkin lymphomas. It aims to help your immune system better recognize and attack the lymphoma and to see how safe the approach is.
Duarte, CaliforniaAges 18 years+ - NCT05437900RecruitingPhase 4
A heart test to guide stent placement using blood-flow measurements
This Phase 4 study tests a way to measure blood flow in heart arteries to help doctors choose the best stent plan. It may help improve safety and effectiveness for people having elective heart stent procedures for stable angina or certain heart attacks.
Aalst, Oost-VlaanderenAges 18–85 - NCT05443516Recruiting
Blood and urine markers in active lupus kidney disease
This study looks at blood and urine markers that may show how active lupus kidney disease is and how it changes over time. It may help doctors better monitor people with active lupus-related kidney inflammation.
BrusselsAges 18–70 - NCT05444452Recruiting
Stent treatment study for blocked heart arteries
This study tests a coronary stent approach for people with significantly blocked heart arteries. It may help by improving blood flow, and it compares treatment in a structured way while monitoring safety and outcomes.
SeoulAges 19 years+ - NCT05447325Recruiting
Brain scans to study vaping to smoking risk
This study uses brain imaging to better predict who might start smoking cigarettes and who might increase nicotine use among young adult e-cigarette (vaping) users. It may help researchers find early warning signals so support can be targeted sooner.
Athens, GeorgiaAges 18–29 - NCT05452031Recruiting
Sleep program for people with dementia and their caregiver
This study tests a “dyadic” sleep health approach, meaning it works with both you and your caregiver together. It aims to improve sleep when dementia is causing frequent sleep problems, and to see whether a caregiver-involved plan helps both of you.
La Jolla, CaliforniaAges 18 years+ - NCT05454774RecruitingEarly Phase 1
Gene therapy for adults with severe hemophilia A
This early-phase study tests an FVIII gene therapy to help your body make more of the missing clotting factor in hemophilia A. It’s aimed at adults with severe low FVIII levels who have already used FVIII replacement products for a long time and have not developed an immune blocker (an inhibitor).
Tianjin, Tianjin MunicipalityAges 18 years+ - NCT05456503RecruitingPhase 3
PET scan study of tau buildup in memory and brain disorders
This Phase 3 study uses a PET/CT scan to measure whether a brain protein called tau (and related disease patterns) builds up in different dementia conditions. The goal is to better match which disorders have which brain changes and how they progress.
Philadelphia, PennsylvaniaAges 18 years+ - NCT05460143Recruiting
Optical brain scanning to study memory and thinking
This study uses brain “optical” and possibly MRI scans to understand how thinking and memory work in people with Lewy body dementia, Alzheimer’s disease, or mild memory problems. It may help researchers find better ways to measure brain changes and cognition over time.
CambridgeAges 18 years+ - NCT05461729Recruiting
Testing a heart rehab timing prediction tool after a heart attack
This study follows people with coronary artery disease who are starting a structured heart rehabilitation program after a heart attack or heart procedures. The trial tests whether it can predict and improve the right timing or planning for cardiac rehab.
Ennepetal, North Rhine-WestphaliaAges 18 years+ - NCT05470127Recruiting
Testing a new prostate biopsy needle against the usual one
This study compares a new prostate biopsy system/needle with the standard biopsy needle during your scheduled prostate biopsy. It looks at how well the procedure collects tissue for diagnosis and how the tissue samples compare.
Cartersville, GeorgiaAges 18–90 - NCT05470205RecruitingPhase 3
Noninvasive blood-pressure measurement to estimate liver portal pressure
This Phase 3 study tests a noninvasive ultrasound-based method to estimate portal hypertension, which is high blood pressure in the liver’s blood vessels. It aims to help doctors measure how severe the liver circulation problem is without needing invasive pressure testing.
Philadelphia, PennsylvaniaAges 18 years+
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Common questions
- Are there clinical trials for musculoskeletal diseases or conditions?
- Yes. Clin2 currently lists 4,063 recruiting musculoskeletal diseases or conditions studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a musculoskeletal diseases or conditions trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a musculoskeletal diseases or conditions trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.