Clinical trials
Musculoskeletal Diseases or Conditions clinical trials
Below are recruiting musculoskeletal diseases or conditions clinical trials, each written for real people, not researchers. We’re tracking 4,026 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06089057Enrolling by invitation
Social exercise program for aging with kidney disease
This study tests a program to help people with chronic kidney disease who are starting to feel frail (weak or slow). It uses social activities and gentle exercise to improve well-being and strength.
Nashville, TennesseeAges Any age - NCT06080659Recruiting
Brain network study for Alzheimer's and Parkinson's
This study uses brain scans to look for patterns that might help diagnose memory or movement problems like Alzheimer's or Parkinson's disease. It compares people with mild symptoms, like forgetfulness or early Parkinson's, to healthy volunteers.
RennesAges 50–80 - NCT06042387Recruiting
Genome study across diverse populations with IBD
This study looks at the genes of people with inflammatory bowel disease (IBD) and healthy volunteers to understand why IBD affects different populations. You may join if you have Crohn's disease, ulcerative colitis, or undetermined IBD, or if you are a healthy person without any IBD history.
Toronto, OntarioAges Any age - NCT06004349Recruiting
Genetic study of autoinflammatory diseases
This study looks for genes linked to autoinflammatory diseases like VEXAS syndrome. You or your family member can join by mailing in a blood or saliva sample to help researchers better understand these conditions.
New York, New YorkAges 1 month+ - NCT05995353RecruitingPhase 3
Risankizumab for children with moderate to severe Crohn's
This study tests a new medicine called risankizumab for children with moderate to severe Crohn's disease. It is given as an IV infusion or a shot under the skin to see if it can reduce inflammation and improve symptoms.
Phoenix, ArizonaAges 2–17 - NCT05992532Recruiting
Study of rare enzyme disorders in monoclonal gammopathy or myeloma
This study looks for two rare inherited disorders—Gaucher disease and acid sphingomyelinase deficiency (ASMD)—in people who already have a blood condition like monoclonal gammopathy (abnormal protein) or multiple myeloma. If you have an enlarged spleen or low platelets, you may be eligible to help researchers understand if these rare diseases are more common in this group.
Vitoria-Gasteiz, AlavaAges 18–99 - NCT05998330Recruiting
Palliative care support for advanced liver disease patients
This study tests whether adding palliative care (extra support for symptoms and planning) during a hospital stay helps people with advanced liver disease and their caregivers feel better and plan ahead.
Boston, MassachusettsAges 18 years+ - NCT05932615Enrolling by invitation
Testing a new transcatheter valve for aortic valve narrowing
This trial studies how safe and effective the NAVITOR valve is for treating narrowed aortic valves placed through a catheter (no open-heart surgery). It may be an option if you’re at intermediate-to-low surgical risk and meet heart ultrasound/CT measurements.
Birmingham, AlabamaAges 18 years+ - NCT05882344Enrolling by invitation
Deep brain stimulation for early Alzheimer’s memory problems
This trial tests whether a targeted deep brain stimulation treatment can help people with early Alzheimer’s disease symptoms and memory loss. It also involves brain imaging and a surgery/anesthesia procedure to place the stimulator.
Nashville, TennesseeAges 60–80 - NCT05819385Recruiting
Study of lung scarring in immune diseases
This is an observational (non-treatment) study that collects information about how interstitial lung disease (lung scarring) happens in people with certain autoimmune or immune-related conditions. It uses patient interviews or existing medical records to better understand the pattern and causes, which may help future care.
Mexico CityAges 18 years+ - NCT05829889Recruiting
FFR test versus angiogram to guide left main heart treatment
This trial compares two ways to decide how to treat a narrowed “left main” coronary artery: a pressure-based test (FFR) versus standard X-ray imaging (angiography). It aims to see which approach better helps choose safe, appropriate treatment using a stent when appropriate.
Hong KongAges 20 years+ - NCT05821634Enrolling by invitation
Personalized telehealth counseling for anxiety and alcohol use
This study personalizes how telehealth counseling is delivered for people dealing with anxiety or trauma-related symptoms and alcohol use problems. It may help by tailoring counseling timing and approach to what you need.
Piscataway, New JerseyAges 18–65 - NCT05727852Enrolling by invitation
Breath and heart tests to study lung disease stiffness
This study uses breath analysis and heart/electrical heart testing to look at how stiff the arteries are in people with long-term lung conditions. It may help researchers better understand lung disease effects on the cardiovascular system.
MoscowAges 18 years+ - NCT05656378Recruiting
Storing samples to study how the body interacts with microbes
This study creates a storage bank of biological samples like blood, stool, and tissue. Researchers will use these samples to learn how the body interacts with the natural microbes that live in and on us, which may help improve treatments for many diseases.
Bethesda, MarylandAges Any age - NCT05659901Recruiting
Study tracks symptoms and test results in PLP1-confirmed PMD
This study follows children with Pelizaeus-Merzbacher disease (PMD) who have a specific genetic change (PLP1 duplication). It aims to learn which body measurements (“biomarkers”) and symptoms change over time, to better understand disease progression.
Atlanta, GeorgiaAges 6 months–17 years - NCT05653466RecruitingPhase 2
Telehealth therapy schedule for stroke-related aphasia patients
This trial tests an approach that adjusts therapy scheduling for people with long-lasting (over 6 months) language problems after a stroke. It may help some patients by matching the therapy timing to what works best for them.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT05653440RecruitingPhase 2
Naming therapy training for chronic post-stroke aphasia
This Phase 2 trial studies a speech therapy approach that teaches people with aphasia how to name words, using different learning methods. You may be able to join if your language problem started after a stroke and has lasted more than 6 months.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT05568498RecruitingPhase 2
Probiotic trial for depression in Parkinson’s disease
This Phase 2 study tests whether taking probiotics can improve depression and mood symptoms in people with Parkinson’s disease. It’s meant for those with mild to moderate depression and stable Parkinson’s and mood treatments.
Vancouver, British ColumbiaAges 40–80 - NCT05552157RecruitingPhase 2/Phase 3
Study of treatments for early onset Alzheimer's caused by genetic mutations
This trial tests potential treatments for people who are at risk for or have early onset Alzheimer's disease due to a specific genetic mutation. It aims to find treatments that could slow or prevent symptoms.
Birmingham, AlabamaAges 18 years+ - NCT05462106RecruitingPhase 1/Phase 2
ACI-24.060 study for early Alzheimer’s in adults and Down syndrome
This Phase 1/2 study tests an Alzheimer’s treatment called ACI-24.060 to see if it affects the disease in people with early Alzheimer’s changes. It includes two groups: older adults with early symptoms and people with Down syndrome who also show Alzheimer’s-related changes on brain scans.
Phoenix, ArizonaAges 35–85 - NCT05435547RecruitingPhase 4
Pre-surgery steroid medicine for autoimmune thyroid disease
This trial tests whether taking corticosteroids (anti-inflammatory medicines) before thyroid surgery is safe and helpful for people with autoimmune thyroid disease. It focuses on Graves’ or Hashimoto’s disease patients who are planning total thyroid removal.
Indianapolis, IndianaAges 18 years+ - NCT05398783Recruiting
Study of how metabolism and body composition change over time
This natural history study follows people to understand how metabolism and body composition vary in health and disease. It may help researchers better measure metabolic changes and understand who is at risk as health and treatments change.
Bethesda, MarylandAges 2–99 - NCT05370014Recruiting
Partner support program for chronic health conditions
This study tests a program that helps patients with chronic health conditions and their care partners work together to improve their health and well-being. If you live in a rural or underserved area in South Carolina and have a condition like diabetes or high blood pressure, you and your support person might be able to join.
Columbia, South CarolinaAges 18 years+ - NCT05333471RecruitingPhase 1/Phase 2
Fecal transplant for chronic bowel inflammation in CGD
This study tests whether transplanting stool microbiome (fecal microbiota transplant) can improve chronic colitis in people with chronic granulomatous disease (CGD). It aims to reduce bowel inflammation and symptoms by changing gut bacteria.
Bethesda, MarylandAges 10–60
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Common questions
- Are there clinical trials for musculoskeletal diseases or conditions?
- Yes. Clin2 currently lists 4,026 recruiting musculoskeletal diseases or conditions studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a musculoskeletal diseases or conditions trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a musculoskeletal diseases or conditions trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.