Clinical trials
Musculoskeletal Diseases or Conditions clinical trials
Below are recruiting musculoskeletal diseases or conditions clinical trials, each written for real people, not researchers. We’re tracking 4,024 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT02504879Recruiting
Study of melorheostosis progression and genetic causes
This study follows adults with suspected or confirmed melorheostosis to understand how the condition develops and what outcomes to expect. It may help researchers better understand the disease and its genetic factors.
Bethesda, MarylandAges 18–90 - NCT02769975Recruiting
Check children and teens with hormone and metabolism problems
This study evaluates children (and sometimes relatives) who may have hormone (endocrine) or metabolism-related conditions. It helps doctors better understand these problems by doing a clinical evaluation.
Bethesda, MarylandAges 3 months–100 years - NCT02579967RecruitingPhase 2
Stem cell transplant for primary immune system disorders
This study tests whether an allogeneic stem cell (bone marrow) transplant can correct an inherited immune problem in people with severe primary immunodeficiencies. It may help reduce life-threatening infections and improve quality of life, depending on your overall health and donor match.
Bethesda, MarylandAges 4–75 - NCT07477197Recruiting
Heart Institute Biobank for Adult Congenital Heart Disease
This study collects blood and tissue samples and health information from adults with or at risk for congenital heart disease or related heart conditions. It aims to help researchers better understand these conditions and improve future treatments.
Cincinnati, OhioAges 16 years+ - NCT07563777Recruiting
Long-term study of human aging and health
This is a long-term research study that follows people over time to understand how humans age. Researchers will collect information about your health and lifestyle to learn what helps people stay healthier as they get older.
Boulder, ColoradoAges 18 years+ - NCT05700526Enrolling by invitation
3D-printed customized bone grafts for children’s limb problems
This trial is testing 3D-printed, customized bone grafts made from donor bone to help children and teens stabilize corrective surgery for limb bone alignment. It may help patients who need a planned bone cut (osteotomy) plus a large bone graft to hold the correction in place.
BolognaAges 2–18 - NCT07420907Recruiting
Tracking heart health over time
This study uses a wearable patch to monitor heart-related signs in people with heart conditions. It aims to learn more about how these conditions progress, which could help improve future care.
Chicago, IllinoisAges 18 years+ - NCT06756009Recruiting
Eye scans to check liver disease and transplant outlook
This study uses advanced eye scans to see if your eyes can give clues about your chronic liver disease and how well you might do after a liver transplant. If you have advanced liver disease or cirrhosis, and are maybe waiting for a transplant, you may join.
Guangzhou, GuangdongAges 18 years+ - NCT06715085RecruitingPhase 4
PRGF injections for chronic low back pain
This trial tests whether injections of a blood-based treatment called PRGF can help people with long-term low back pain caused by worn discs. It is for those who haven't gotten relief from standard treatments like medication.
Vitoria-Gasteiz, AlavaAges 18 years+ - NCT06889896Enrolling by invitation
Blood test for Alzheimer's brain changes
This study uses a simple blood test to quickly detect Alzheimer's-related brain changes (amyloid plaques). It may help people with memory concerns avoid a more invasive PET scan and get answers faster.
Hefei, AnhuiAges 45–85 - NCT06548958Recruiting
TBI and chemotherapy before a second stem cell transplant
This trial tests a combination of total body irradiation and two chemotherapy drugs as preparation for a second stem cell transplant in people with blood cancers that relapsed or didn't respond to the first transplant.
Suzhou, JiangsuAges 14–70 - NCT06509087Recruiting
Combining CT and MRI for joint pain procedure
This study tests a procedure called transarterial microembolization for chronic shoulder or knee pain that hasn't improved with other treatments. It uses both CT and MRI to guide the procedure and see if it can help reduce pain.
TaipeiAges 20–80 - NCT07632755Recruiting
Memory Training Using Movement for Early Alzheimer's Disease
This study tests whether learning memory strategies through physical movement and motor activities can help people with early Alzheimer's disease improve their memory. Researchers will compare people with early Alzheimer's to healthy older adults to see if this approach is effective.
GrenobleAges 60 years+ - NCT02675959RecruitingPhase 2
Transplant with defibrotide for sickle cell disease
This trial tests a stem cell transplant from a half-matched donor using a strong conditioning regimen and a drug called defibrotide to protect organs. It aims to cure sickle cell disease in patients who have had serious complications like stroke, chest syndrome, or frequent pain episodes.
Los Angeles, CaliforniaAges 6 months–21 years - NCT07245706Recruiting
Shoulder Health After Rehab and Performance Training
This study looks at how shoulder health changes after a rehabilitation and performance training program for people with paraplegia who use manual wheelchairs. It may help you strengthen your shoulders and prevent injuries as you start your life after rehab.
Nottwil, Canton of LucerneAges 18–70 - NCT03777267Recruiting
Test a brain-sensing device for stress, anxiety, or insomnia
This exploratory study tests how a wearable brain-sensing setup (with sensor leads/earbuds) works for people with stress, anxiety, or sleep problems. You may be asked to sit still during sessions and complete brief questionnaires to confirm your symptoms.
Winston-Salem, North CarolinaAges 11 years+ - NCT03867448Recruiting
Study of Hormone Conditions and How the Body Works
This study looks at people with known or suspected hormone (endocrine) conditions. It aims to improve understanding and clinical screening so doctors can better manage these conditions over time.
Bethesda, MarylandAges 18–90 - NCT04580225Recruiting
Tested partial wrist fusion with or without bone removal
This study compares two surgical options for certain types of advanced wrist arthritis—one with partial wrist fusion alone, and one with partial wrist fusion plus removal of a small wrist bone. It may help find which approach works better for pain and function after surgery.
Calgary, AlbertaAges 18–75 - NCT04873258Recruiting
Test a non-invasive tool to screen for fat-related liver disease
This study looks at a new non-invasive screening method to predict metabolic dysfunction–associated steatotic liver disease (MASLD), a condition where fat builds up in the liver. The goal is to help identify people who may be at risk without needing invasive tests.
London, LondonAges 18–80 - NCT05440422RecruitingPhase 2
Anifrolumab to improve blood vessel risk markers in lupus
This Phase 2 trial tests anifrolumab, a lupus medicine, to see if it can improve blood vessel “risk markers” in people with systemic lupus erythematosus (SLE). The study is especially focused on SLE-related problems that can affect heart and blood vessel health.
Bethesda, MarylandAges 18–80 - NCT05471752Recruiting
Study of special cells taken during orthopedic surgery
This study collects small cell samples from certain body tissues during planned orthopedic surgeries. The researchers will study these cells to understand their potential use in future treatments and to see if using them is safe and helpful.
MilanAges 18 years+ - NCT05525507RecruitingPhase 1
Test early immune-tolerance treatment for matched kidney transplant patients
This Phase 1 study tests a treatment plan given after a kidney transplant to help the immune system stay calm and reduce the risk of rejection. Participants must have a well-functioning kidney transplant from a closely matched living donor and meet health and safety requirements.
Los Angeles, CaliforniaAges 18 years+ - NCT05554224Recruiting
Personalized treatment based on obesity-related fatty liver tests
This study uses multiple types of health data (“multi-omics”) to help choose a personalized treatment plan for people with obesity-related fatty liver disease. It may help match treatment to your biology to improve outcomes.
Reus, TarragonaAges 18 years+ - NCT05578495Recruiting
Track daily movement to predict future health problems
This study looks at how active versus sedentary you are (often using a digital signature from your daily routine) to see how it relates to developing multiple health conditions over time. It may help researchers understand which activity patterns are linked with higher risk, especially in certain long-term illnesses.
Clermont-FerrandAges 18–90
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Common questions
- Are there clinical trials for musculoskeletal diseases or conditions?
- Yes. Clin2 currently lists 4,024 recruiting musculoskeletal diseases or conditions studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a musculoskeletal diseases or conditions trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a musculoskeletal diseases or conditions trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.