Clinical trials
Musculoskeletal Diseases or Conditions clinical trials
Below are recruiting musculoskeletal diseases or conditions clinical trials, each written for real people, not researchers. We’re tracking 4,026 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06632600RecruitingPhase 2
Study of LXE408 for people with chronic Chagas disease
This trial tests a new drug called LXE408 for people with chronic Chagas disease. It aims to see if the drug is safe and effective, and participants will also receive standard treatment with benznidazole.
Sylmar, CaliforniaAges 18–60 - NCT06642519Enrolling by invitation
Brain-computer interface for freezing of gait in Parkinson's
This study tests a brain-computer interface device to help people with Parkinson's disease who experience freezing of gait. The goal is to see if the device can reduce freezing episodes when medication isn't enough.
Toronto, OntarioAges Any age - NCT06634628RecruitingEarly Phase 1
Testing a new brain scan tracer for Huntington's disease
This trial tests a new radioactive tracer called [11C]CHDI-00491009 that may show mutant huntingtin protein in the brain using a PET scan. It aims to find out if the tracer is safe and helps see Huntington's disease changes. If you have early-stage Huntington's or are a healthy volunteer, you may be able to join.
LeuvenAges 18–64 - NCT06627751RecruitingPhase 2
Mezigdomide, Carfilzomib, and Dexamethasone for Relapsed Myeloma
This clinical trial tests a combination of three drugs—mezigdomide, carfilzomib, and dexamethasone—for people with multiple myeloma that has come back or stopped responding to prior treatments, especially when the disease has spread outside the bone (extramedullary disease). It aims to see if this new cocktail can shrink tumors and control myeloma more effectively.
Buffalo, New YorkAges 18 years+ - NCT06619561RecruitingPhase 2
Testing vimseltinib for chronic graft versus host disease
This trial tests a new drug called vimseltinib for people with active chronic graft versus host disease (cGVHD) that hasn't gotten better after at least two prior treatments. The goal is to see if vimseltinib can help control the condition.
Duarte, CaliforniaAges 18 years+ - NCT06613438Recruiting
New wearable device for GERD symptoms
This study tests a new wearable device (eGERD) that aims to reduce symptoms of GERD (heartburn and regurgitation). The trial will check if the device is safe and works well without needing medication.
Chicago, IllinoisAges 22–75 - NCT06609226RecruitingPhase 3
Long-term safety study of etavopivat for sickle cell disease or thalassaemia
This study looks at the long-term safety and benefits of taking etavopivat for people with sickle cell disease or thalassaemia who have already been helped by it in a previous trial. It aims to see if staying on the treatment continues to be safe and effective.
Birmingham, AlabamaAges 2 years+ - NCT06611111RecruitingEarly Phase 1
Ceftriaxone for lingering fatigue after Lyme disease
This study tests whether a short course of a strong antibiotic (ceftriaxone) can help people who still have fatigue and other symptoms after being treated for Lyme disease. It aims to see if this treatment can improve your quality of life.
East Syracuse, New YorkAges 18–75 - NCT06615453Recruiting
Tixel treatment for dry eye disease and periorbital wrinkles
This study tests a device called Tixel that may help reduce wrinkles around the eyes and improve dry eye symptoms. If you have mild to moderate under-eye wrinkles and dry eyes that bother you a lot, this treatment might be an option.
BirminghamAges 18 years+ - NCT04042844RecruitingPhase 2
Single injection treatment for chronic low back disc pain
This Phase 2 study tests whether one injection of BRTX 100 can reduce pain and improve function in people with chronic, disc-related low back pain. It looks for whether the treatment is safe and works better than what you’ve already tried.
Birmingham, AlabamaAges 18 years+ - NCT06585384RecruitingPhase 1
Safety of etanercept with contrast ultrasound for Alzheimer's
This study tests whether combining a drug called etanercept with repeated contrast ultrasound is safe for people with mild Alzheimer's. It aims to see if this approach can help slow the disease.
ParisAges 50–85 - NCT06584357Recruiting
Digital and blood markers linked to brain scans in older adults
This study is looking for older adults (60–90) who are either cognitively normal, have mild cognitive impairment (MCI), or have mild-to-moderate Alzheimer's dementia. It aims to see how digital tests and blood-based markers relate to brain scans (amyloid and tau PET). You will need a study partner, undergo MRI and PET scans, and give blood samples.
Atlantis, FloridaAges 60–90 - NCT06585449RecruitingPhase 1
Study of ALN-HTT02 for Huntington's disease
This trial tests an experimental drug called ALN-HTT02 for people with Huntington's disease. The goal is to see if it can help manage symptoms. Participants must have stage 2 or early stage 3 Huntington's disease.
EdmontonAges 25–70 - NCT06600412RecruitingPhase 2
Testing R3R01 for protein in urine from diabetic kidney disease
This trial tests if a new drug, R3R01, can help reduce protein leaking into the urine in people with diabetic kidney disease. It may offer a new option for managing kidney health.
Copenhagen, CopenhagenAges 18 years+ - NCT06585774RecruitingPhase 3
Axatilimab plus steroids for new chronic GVHD
This study tests a new drug called axatilimab combined with steroids as a first treatment for chronic graft-versus-host disease (GVHD) after a stem cell transplant. It aims to see if this combination helps control symptoms better than steroids alone.
Birmingham, AlabamaAges 12 years+ - NCT06585787RecruitingPhase 3
Testing KarXT for psychosis in Alzheimer’s disease
This study tests an investigational medication (KarXT) for treating psychosis—hallucinations or delusions—in people with Alzheimer’s disease. It aims to see if the drug can reduce these symptoms safely and effectively.
Chandler, ArizonaAges 55–90 - NCT06588920Recruiting
Brain activity, thinking, and walking study for Parkinson's
This study looks at how brain activity relates to thinking and walking in people with Parkinson's disease. It may help understand the connections between these functions.
TaipeiAges 40–80 - NCT06569758RecruitingPhase 1
A study of GenSci098 for active thyroid eye disease
This study tests a new medication called GenSci098 for people with active thyroid eye disease. It aims to reduce eye symptoms like redness, swelling, and bulging, and improve quality of life.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT06578507RecruitingPhase 2
Twice-daily hydroxyurea liquid for children with sickle cell disease
This trial tests a new twice-daily liquid form of hydroxyurea (a common SCD medicine) in children ages 9 months to 11 years with sickle cell disease. It will check how the medicine works in the body, if it is safe, and if it helps reduce pain crises and other complications.
CréteilAges 9 months–11 years - NCT06581328RecruitingPhase 4
Study of vedolizumab for ulcerative colitis or Crohn's disease
This study tests a medication called vedolizumab for people with moderate to severe ulcerative colitis or Crohn's disease. The goal is to see how well it works in a regular community setting, and it may help control symptoms if other treatments haven't worked.
Birmingham, AlabamaAges 18–80 - NCT06574152Recruiting
Light therapy for pain relief after dental root surgery
This trial tests whether a special light treatment, called photobiomodulation, can help reduce pain and speed up healing after a specific type of dental surgery on the root of a tooth. The surgery involves a small cut in the gum, and the light may help the gum recover faster.
Houston, TexasAges 18 years+ - NCT06572267RecruitingPhase 2
Meplazumab for coronary artery disease
This trial tests if meplazumab can help people with chronic coronary syndrome who have stable angina. It focuses on patients with certain fatty deposits around their heart arteries that show up on a special CT scan.
Xi'an, ShannxiAges 18 years+ - NCT06574581RecruitingPhase 1/Phase 2
Adipose stem cells for connective tissue disease with lung scarring
This trial tests whether stem cells from fat tissue can help people with connective tissue diseases (like lupus or scleroderma) whose lung scarring has worsened despite standard treatments. It aims to slow or stop lung damage.
TaichungAges 20–80 - NCT06582212Recruiting
Managing Hormonal Triggers in Women with Parkinson's
This study helps women with Parkinson's disease who are still having periods learn how hormonal changes may affect their symptoms. You will be guided to identify and manage these triggers better.
GrenobleAges 18–56
Hear when a new Musculoskeletal Diseases or Conditions trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for musculoskeletal diseases or conditions?
- Yes. Clin2 currently lists 4,026 recruiting musculoskeletal diseases or conditions studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a musculoskeletal diseases or conditions trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a musculoskeletal diseases or conditions trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.