Clinical trials
Neck Pain clinical trials
Below are recruiting neck pain clinical trials, each written for real people, not researchers. We’re tracking 166 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07125027Recruiting
Exercise and mindfulness for sciatica pain
This study tests a program called Move-MORE that combines exercise and mindfulness to help people with nerve-related leg pain (sciatica) that has lasted at least 3 months. You would use the program at home, attend weekly video sessions for 8 weeks, and complete questionnaires and daily surveys to see if the program improves your pain and quality of life.
Portland, OregonAges 18–75 - NCT07082972RecruitingPhase 4
Study of splint therapy and Botox for jaw muscle pain
This trial compares two treatments—a dental splint and Botox injections into the jaw muscle (masseter)—to see which one better relaxes head and neck muscles in people with myofascial pain syndrome. It may help you if you have facial pain related to muscle tension.
Istanbul, VeznecilerAges 18–55 - NCT07405645Recruiting
Focused Ultrasound for Cancer Pain in the Head or Neck
This trial tests a non-invasive focused ultrasound treatment aimed at a specific brain area to reduce severe cancer-related pain in the head, neck, or upper chest. It may help if your pain hasn't responded to standard medications.
Boston, MassachusettsAges 18–85 - NCT01788410Recruiting
MRI-guided freezing treatment for neck, head, and spine pain
This trial studies an MRI-guided procedure that “freezes” targeted nerves or joints to reduce pain in the head, neck, or spine. It may help if your pain comes from a joint problem or a compressed/damaged nerve and you can safely have MRI scans before and after the treatment.
Boston, MassachusettsAges 18 years+ - NCT07442721Recruiting
Comparing two types of nerve blocks for hip replacement pain
This study compares two different nerve block methods to see which provides better pain relief for people having a partial hip replacement. It will help doctors choose the best way to manage pain after surgery.
El Fayoum Qesm, Faiyum GovernorateAges 50–90 - NCT07707401Recruiting
WeChat neck exercises for recovery after thyroid surgery
This study tests whether simple neck exercises, guided through the WeChat app, can help you recover more quickly after thyroid surgery. If you have no serious complications and don't have neck problems, you may be able to join.
Shanghai, Shanghai MunicipalityAges 18–60 - NCT05156060RecruitingPhase 1/Phase 2
Gabapentin and ketamine to treat head and neck cancer pain
This early-phase study tests whether gabapentin and a ketamine nasal spray can help prevent or lessen short-term and long-term pain from locally advanced head and neck cancer. It may help by changing how the nervous system responds to pain during and after radiation and chemoradiation.
Nashville, TennesseeAges 21 years+ - NCT07814833Recruiting
Neck and shoulder exercises for chronic neck pain from cervical spondylosis
This study tests two different exercise programs for neck pain caused by cervical spondylosis (wear-and-tear on the neck bones). One program focuses on deep neck muscles with a pressure device, and the other adds shoulder exercises. The goal is to see which approach better reduces pain, improves movement, and lessens neck disability.
Rawalpindi, Punjab ProvinceAges 40–60 - NCT07233538Recruiting
Numbing injection before nose surgery for better pain relief
This study tests a numbing injection in the cheek area before septorhinoplasty to see if it improves pain control and reduces the need for strong IV pain medicine. It may help you have a smoother recovery with less discomfort.
Ankara, YenimahalleAges 18–65 - NCT06912438Enrolling by invitation
Emotional release after dry needling for jaw and head pain
This study tests whether a dry needling technique (trigger point needling) can help release emotional tension and reduce pain from muscle knots in the head and neck. It may be a good option if you have jaw or headache pain related to muscle tightness.
Tel Aviv, IsraelAges 18 years+ - NCT07857655RecruitingPhase 4
Intraoperative methadone for pain after head and neck cancer surgery
This trial tests whether giving methadone during your head and neck cancer surgery helps control pain right after the operation. Methadone is a long-acting painkiller that might reduce pain for up to a day or more, potentially improving your recovery experience.
Portland, OregonAges 18–89 - NCT06985784Recruiting
Virtual reality for head and neck cancer patients and caregivers
This study tests whether using virtual reality can help reduce depression, anxiety, and pain in people with head and neck cancer and their caregivers. You and your caregiver may be able to use VR headsets together as part of your treatment.
Duarte, CaliforniaAges 18 years+ - NCT06078371Recruiting
Opioid-free pain treatment after broken bone surgery
This study compares standard pain treatment using opioids to a new opioid-free pain block for people who had surgery for broken bones. The goal is to find safer, non-addictive ways to manage pain after trauma.
Kansas City, KansasAges 18 years+ - NCT05023369RecruitingPhase 4
Hip replacement patients may get an added steroid injection
This trial tests whether a steroid injection placed around the hip after hip replacement can reduce pain and shorten hospital stay. It is meant for older adults who are having hip replacement due to a broken femoral neck bone.
LuganoAges 50–90 - NCT06992427RecruitingPhase 3
Gabapentin to prevent opioid use for mouth pain during cancer treatment
This trial tests if taking gabapentin during chemoradiation for head and neck cancer can reduce the need for strong painkillers like opioids. It may help manage mouth pain caused by treatment.
Gilbert, ArizonaAges 18 years+ - NCT07711626Recruiting
Foot massage and ear stimulation for head and neck cancer symptoms
This study tests whether foot massage (reflexology) and a mild nerve-stimulation device on the ear can help reduce side effects during chemotherapy and radiation for head and neck cancer.
Hualien CityAges 30–75 - NCT07090551Recruiting
Mouthguard for jaw and neck muscle pain from grinding
This study tests whether a custom mouthguard (occlusal splint) can reduce pain and tension in the jaw and neck muscles. It is for people with bruxism (teeth grinding) and myofascial pain, a type of muscle pain in the jaw area.
IstanbulAges 18–50 - NCT05635929Recruiting
Topical treatment to reduce mouth sores during or after radiation
This study tests a new cream/gel applied to the mouth to lower the chance of severe mouth sores in people receiving radiation for head and neck cancer. It also looks at how treatment affects quality of life using patient questionnaires.
Madrid, MadridAges 18 years+ - NCT07211308Recruiting
A study of spinal cord stimulation for chronic leg pain
This trial tests a type of spinal cord stimulation (DTM SCS) for people with chronic leg or foot pain caused by nerve damage (PSPS-T2). It aims to see if this treatment can safely reduce pain and improve daily life.
BrusselsAges Any age - NCT07672236RecruitingPhase 3
Comparing two mouth pain treatments for head and neck cancer patients
This trial tests a new mouthwash (BupiZenge) against a standard numbing medicine (lidocaine) for pain caused by mouth sores from radiation therapy. It may help you if you are about to start radiation for certain head and neck cancers.
CopenhagenAges 18–80 - NCT06575322Recruiting
Neoadjuvant therapy for head and neck cancer: effects on pain and mood
This trial tests whether adding immunotherapy to chemotherapy before surgery can help reduce pain, anxiety, and depression in people with head and neck cancer. The goal is to see if this approach improves quality of life during treatment.
Guanzhou, GuangdongAges 18–80 - NCT07212036Recruiting
Ultrasound for elbow fractures in children
This study uses ultrasound, a sound-wave imaging tool, to diagnose elbow fractures in children. It aims to see if ultrasound works as well as X-rays, so your child might avoid radiation.
Orlando, FloridaAges Up to 18 years
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Common questions
- Are there clinical trials for neck pain?
- Yes. Clin2 currently lists 166 recruiting neck pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a neck pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a neck pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.