Clinical trials
Nervous System Diseases clinical trials
Below are recruiting nervous system diseases clinical trials, each written for real people, not researchers. We’re tracking 270 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06959199Recruiting
Treating stroke beyond 24 hours with artery-opening procedure
This study tests whether opening a blocked large artery in the brain up to 5 days (or even 7 days if symptoms are worsening) after a stroke can improve outcomes. It uses a catheter-based treatment (endovascular therapy) for people who have not responded to standard care and have limited brain damage so far.
Hefei, AnhuiAges 18 years+ - NCT07137494RecruitingPhase 1
CAR T-cell therapy for CNS lymphoma
This trial tests a new type of CAR T-cell therapy (MB-CART19.1) for people with central nervous system lymphoma (CNSL) that has come back or not responded to treatment. It aims to see if this therapy can help treat the lymphoma in the brain or spinal fluid.
Basking Ridge, New JerseyAges 18 years+ - NCT07185022Recruiting
Clot-busting drug through artery for medium-vessel stroke
This trial tests a clot-busting drug given directly into the arteries of the brain for people who have had a stroke due to a blockage in a medium-sized artery. It aims to see if this treatment can help improve recovery when started up to 72 hours after symptoms begin.
Fuyang, AnhuiAges 18 years+ - NCT07288385Recruiting
Virtual reality and brain stimulation for arm recovery after stroke
This study tests if using virtual reality along with mild brain stimulation can help improve arm and hand movement in people who have had a stroke. It is for those who are at least three months past their stroke and have moderate arm weakness.
RiyadhAges 18 years+ - NCT07324330Recruiting
Slowing cognitive decline with exercise in iRBD
This study tests if increasing physical activity can help slow down cognitive (thinking) decline in people with iRBD, a sleep disorder that often leads to Parkinson's or dementia. You'll use a smartphone and a FitBit to track your activity and receive coaching.
Bonn, North Rhine West-FaliaAges 50–80 - NCT00004568Recruiting
Study of inherited neurological disorders and family genetics
This research study evaluates people with inherited neurological conditions (nervous system disorders that run in families) and their relatives. Researchers aim to better understand these conditions and improve diagnosis through clinical exams and genetic testing.
Bethesda, MarylandAges 2–120 - NCT00794352Recruiting
Studying immune brain and nerve conditions with tests and samples
This study looks at how immune-related brain or spinal cord illness shows up using exams, MRI scans, and sometimes a spinal fluid test (lumbar puncture), plus collected blood and other samples. It may help researchers better understand these conditions and improve future diagnosis or treatments.
Bethesda, MarylandAges 1 month–99 years - NCT02435810Recruiting
Study of infections and inflammation affecting the nervous system
This study looks at how infections or inflammation involving the brain and spinal cord work, using patient data and samples. It may help researchers better understand these illnesses and improve future care.
Bethesda, MarylandAges 2–110 - NCT02795052Recruiting
Stem cell treatment trial for nerve injury
This study tests whether bone-marrow stem cells can improve nerve function in people with nerve damage that usually doesn’t recover with current care. It also checks whether the treatment is safe and whether people can be followed over time with repeated nerve exams.
Westport, ConnecticutAges 18 years+ - NCT02725060Enrolling by invitation
Study of autoimmune changes in postural tachycardia syndrome
This trial studies whether an autoimmune (immune system–related) process is involved in postural tachycardia syndrome (POTS), a condition where your heart rate rises when you stand. The study may help researchers understand what causes POTS and how it could be treated or monitored.
Oklahoma City, OklahomaAges 18–50 - NCT07476781Recruiting
Liquid biopsy study for solid tumours and brain tumours
This study collects samples of spinal fluid and blood from people with solid tumours that have spread to the brain or spine, or who have primary brain tumours. The goal is see if these samples can help doctors detect and monitor these cancers more easily.
Toronto, OntarioAges 18 years+ - NCT06203626Recruiting
Portable MRI for brain imaging at the bedside
This study is testing a new, portable MRI machine that can be used right at your bedside. It aims to see if it can take clear pictures of the brain for people with strokes, brain conditions, or symptoms of a brain problem.
Bethesda, MarylandAges 3–99 - NCT06626919RecruitingPhase 1
A cell therapy trial for generalized myasthenia gravis
This trial tests a new cell therapy called anitocabtagene autoleucel (anito-cel) for people with generalized myasthenia gravis (gMG) that is not well controlled with current treatments. The goal is to see if it can reduce symptoms and improve quality of life.
Los Angeles, CaliforniaAges 18 years+ - NCT07056348Recruiting
Brain stimulation to improve movement in Parkinson's or tremor
This study tests brain stimulation in a region called VOP/VIM to see if it can improve motor function. It is for people with movement disorders who are already getting deep brain stimulation (DBS) surgery.
Pittsburgh, PennsylvaniaAges 18–80 - NCT03270059RecruitingPhase 2
MRI with special contrast to study brain and other CNS problems
This trial tests whether two special MRI contrast medicines—gadolinium and ferumoxytol—can better diagnose problems in the brain or central nervous system. It may help doctors identify what’s causing symptoms or abnormal brain findings.
Portland, OregonAges 10 years+ - NCT07126821Recruiting
Brain disease diagnosis study using vision and language
This trial tests a new computer model that combines brain MRI scans and clinical data to help diagnose brain diseases. It may help doctors make more accurate diagnoses.
Changsha, HunanAges Any age - NCT07167043Enrolling by invitation
AI assistant for reading brain CT and MRI scans
This study tests an AI system that helps doctors read brain CT and MRI scans. If you had a brain scan for possible tumors, stroke, injury, or other conditions, your data could be used to improve this tool.
BeijingAges Any age - NCT05209620RecruitingPhase 2
Orelabrutinib plus pemetrexed for lymphoma in the brain
This Phase 2 trial tests a combination medicine (orelabrutinib with pemetrexed) to treat lymphoma that has returned or is not responding, specifically in the brain or spinal fluid. If you qualify, the goal is to shrink measurable tumors and improve control of central nervous system lymphoma.
Zhengzhou, HenanAges 18–75 - NCT05625594RecruitingPhase 1
Test brain-directed CAR T cells for CNS lymphoma
This Phase 1 study tests a new type of immune therapy (CAR T cells) placed directly into the fluid around the brain to treat central nervous system (CNS) lymphoma. It mainly looks at safety and how well the treatment can control the lymphoma when other CNS treatments have not worked.
Duarte, CaliforniaAges 18 years+ - NCT04185038RecruitingPhase 1
CAR T therapy through a catheter for pediatric brain tumors
This Phase 1 trial tests a personalized immune-cell treatment (CAR T) delivered directly in the brain-area space using a catheter. It may help children and young adults with hard-to-treat (recurrent or refractory) diffuse midline brain tumors like DIPG/DMG when standard options aren’t working.
Seattle, WashingtonAges 1–26 - NCT04541082RecruitingPhase 1
Oral ONC206 for recurrent brain and spinal tumors
This early-phase study tests an oral medicine called ONC206 in adults with recurrent, rare brain or spinal cord tumors. The goal is to find a safe dose and look for signs the treatment can shrink or control the cancer.
Bethesda, MarylandAges 18 years+ - NCT06054295Recruiting
Twin study of childhood brain tumors
This study looks at genetic differences between identical twins where only one twin has a childhood brain or spinal cord tumor. It helps researchers understand why some children get cancer and others don't.
Minneapolis, MinnesotaAges Up to 18 years - NCT07539441RecruitingPhase 1/Phase 2
Mirdametinib for brain and nervous system tumors
This trial tests a drug called mirdametinib for people with specific types of brain tumors or neurohistiocytosis (a rare condition affecting the nervous system). The drug targets mutations that cause these conditions to grow.
Basking Ridge, New JerseyAges 18 years+ - NCT07471984Enrolling by invitation
Checking how AI reads brain scans for better diagnosis
This study tests a new AI tool to see if it can help doctors better understand brain MRI and CT scans. It may find issues like strokes, bleeding, tumors, or injuries.
BeijingAges Any age
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Common questions
- Are there clinical trials for nervous system diseases?
- Yes. Clin2 currently lists 270 recruiting nervous system diseases studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a nervous system diseases trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a nervous system diseases trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.