Clinical trials
Neuromodulation clinical trials
Below are recruiting neuromodulation clinical trials, each written for real people, not researchers. We’re tracking 192 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06990295Recruiting
Ultrasound spleen stimulation for sepsis shock
This trial tests if using focused ultrasound to stimulate the spleen can reduce inflammation in septic shock. It may help patients in the ICU who need strong blood pressure support.
Wuhu, AnhuiAges 18 years+ - NCT06596447Recruiting
Brain activity study for severe OCD before DBS surgery
This study looks at how the brain processes approach and avoidance in people with severe OCD that hasn't improved with standard treatments. It aims to understand brain patterns that could help guide a future treatment called deep brain stimulation (DBS).
Houston, TexasAges 22–64 - NCT05207943Recruiting
Testing an at-home device for ACL knee injuries
This study tests whether the NXSignal device can help people recover from an anterior cruciate ligament (ACL) injury. You’d use the device while the study team monitors your progress using questionnaires.
Las Palmas de Gran Canaria, Las PalmasAges 16 years+ - NCT06434831Recruiting
Nerve response study during sacral neuromodulation for overactive bladder
This trial is for people with overactive bladder who are already scheduled to receive a nerve stimulator implant (sacral neuromodulation). The study will measure how your body's automatic nervous system responds when the device is turned on, which may help doctors understand how the treatment works.
LilleAges 18 years+ - NCT06386510Recruiting
Nerve stimulation to improve arm function after stroke
This trial tests whether stimulating certain nerves in the head can help improve arm movement and brain recovery in people who had a stroke more than 6 months ago. It may be an option if you still have some arm movement but are not currently in rehab.
Laval, QuebecAges 18–85 - NCT06213012Recruiting
Spinal stimulation and rehabilitation for walking recovery after spinal cord injury
This study tests whether non-invasive electrical stimulation of the spinal cord, combined with physical therapy, can improve your ability to stand and walk after a spinal cord injury. It explores how your brain and spinal cord can adapt and rebuild connections to help you move better.
Houston, TexasAges 22–75 - NCT06150599Recruiting
Sacral nerve stimulation for chronic pelvic pain
This study tests whether a pacemaker-like device placed near the tailbone can reduce long-term pelvic pain in women who haven't gotten relief from other treatments.
Royal Oak, MichiganAges 22–70 - NCT05921253RecruitingEarly Phase 1
Check a brain-heart device to reduce chemo heart risk
This early-phase study tests a “neuromodulation” device (stimulating nerves that may affect the heart and blood vessels) to help lower cardiovascular risks after certain cancer chemotherapy. It may be most relevant if you recently had an anthracycline-based treatment and also have other heart-risk factors.
Oklahoma City, OklahomaAges 18–99 - NCT05404581Recruiting
Insula brain stimulation for long-term nerve pain
This trial tests whether stimulating a specific brain area (the insula) can reduce chronic nerve pain. It is for people whose pain has lasted at least 6 months and has not improved enough with several pain medicines and other procedures.
Charlottesville, VirginiaAges 18–80 - NCT05230732Recruiting
Test a nerve-stimulation approach for heart inflammation
This trial studies a nerve-stimulation treatment to affect inflammation and blood vessel function in people with systolic heart failure. If you qualify, it may help improve how your heart and blood vessels work.
Oklahoma City, OklahomaAges 18–85 - NCT02331979Recruiting
Neuromodulation trial to improve bladder function after spinal injury
This trial tests a nerve-stimulation approach to improve bladder control in people with spinal cord injury. It specifically targets bladder problems that require clean intermittent catheter use and includes regular testing over 6 months.
Los Angeles, CaliforniaAges 18–45 - NCT06561828RecruitingEarly Phase 1
Brain stimulation study for learning and decision-making
This study uses a non-invasive brain stimulation technique called TMS (transcranial magnetic stimulation) to see if it can improve how people learn and make decisions. It is for healthy adults who are right-handed.
Baltimore, MarylandAges 18–45 - NCT03825575Recruiting
Nerve stimulation to help control bowel leaks
This study looks at using a small nerve stimulation approach to improve fecal incontinence (bowel leaks). If it works for you, it could help you have more control and fewer accidents.
Hamilton, OntarioAges 6–80 - NCT03819062Recruiting
Stomach–bowel nerve stimulation for long-term constipation
This trial studies a device that stimulates nerves near the lower back (sacrum) to improve bowel function in people with severe constipation that hasn’t responded to standard treatments. It may help if your constipation involves problems coordinating bowel movement and the muscles around the rectum.
Hamilton, OntarioAges 6–70 - NCT05798143Recruiting
Testing brain-signal biomarkers in treatment-resistant depression
This trial studies signs in the brain (biomarkers) during an accelerated form of nerve stimulation to treat depression that hasn’t improved with usual antidepressants. It may help researchers learn who benefits and how to better personalize treatment.
ChietiAges 18–65 - NCT06121232Recruiting
Nerve stimulation study for chemotherapy-related nerve pain
This study tests a nerve stimulation treatment to see if it can help reduce pain and improve feeling in the feet for people with nerve damage caused by chemotherapy. You will receive the treatment and have some tests to measure how your nerves are working.
Houston, TexasAges 18 years+ - NCT07868614Recruiting
Comparing brain signal recordings during deep brain stimulation surgery
This study compares a new device for recording brain signals during deep brain stimulation (DBS) surgery with the standard equipment. DBS is a treatment for movement disorders like Parkinson's disease that uses a device to send electrical signals to specific parts of the brain.
Rochester, MinnesotaAges 18 years+ - NCT05048251Recruiting
Targeted brain stimulation for OCD with contamination symptoms
This study tests a personalized brain-stimulation approach to help people with obsessive-compulsive disorder (OCD) focused on contamination worries. If you have the “contamination” type of OCD and meet the safety and medication rules, you may be able to join and see whether this targeted treatment reduces symptoms.
Belmont, MassachusettsAges 18–55 - NCT06000592Recruiting
Spinal stimulation to stabilize blood pressure after spinal cord injury
This trial tests whether a non-invasive device that sends gentle electrical pulses to the spinal cord can help people with a recent spinal cord injury keep their blood pressure steady. It's designed for those who experience low blood pressure when sitting or standing, which can cause dizziness or fainting.
New York, New YorkAges 14–100 - NCT06374433Recruiting
How the brain learns: a brain stimulation study
This study explores how the brain learns and adapts (called brain plasticity) using a non-invasive brain stimulation technique. It may help understand learning and perception in healthy young adults.
MilanAges 18–35 - NCT06467253Recruiting
Brain stimulation plus memory training for mild memory loss
This study tests two gentle brain stimulation methods combined with memory training for people with mild memory loss. It aims to help improve thinking and memory skills over 8 weeks at a psychiatric hospital in Mexico City.
Mexico CityAges 55–85 - NCT07785362Enrolling by invitation
Brain stimulation for teens with fibromyalgia or chronic pain
This study tests a non-invasive brain stimulation technique to see if it can reduce pain in teenagers and young adults with fibromyalgia or other long-lasting muscle and bone pain that hasn't responded to usual treatments. It aims to help calm overactive pain signals in the brain.
Genova, GEAges 10–21 - NCT07786714Recruiting
Faster brain stimulation for early psychosis risk
This study tests a faster type of brain stimulation, called accelerated neuromodulation therapy, in people who have early signs that could lead to psychosis. The goal is to see if this treatment can help reduce symptoms and improve daily life.
Verdun, QuebecAges 18–34 - NCT06505460Recruiting
Brain stimulation for Parkinson's freezing of gait
This study is testing if two brain-stimulation treatments—deep brain stimulation (DBS) or focused ultrasound—can help reduce freezing of gait (a common, frustrating symptom where your feet feel stuck when walking) in people with Parkinson's. Researchers will use brain scans and electrical recordings to understand how these treatments work.
TaichungAges 20–90
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Common questions
- Are there clinical trials for neuromodulation?
- Yes. Clin2 currently lists 192 recruiting neuromodulation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a neuromodulation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a neuromodulation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.