Clinical trials
Neuropathy clinical trials
Below are recruiting neuropathy clinical trials, each written for real people, not researchers. We’re tracking 274 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07704931Enrolling by invitation
Can spinal cord stimulation repair small nerve fibers?
This study tests whether a special type of spinal cord stimulation (which uses mild electrical pulses to block pain) can help repair damaged small nerve fibers in people with small fiber neuropathy. If you have chronic nerve pain and meet the criteria, you may be able to join.
Grand Island, NebraskaAges 19 years+ - NCT03475173Recruiting
Non-invasive eye scans for healthy and specific retinal problems
This study tests new, non-invasive ways to measure how the retina (the light-sensing part of the eye) is structured and how well it works. It may help researchers better understand certain vision disorders and how to track them, without surgery or injections.
Iowa City, IowaAges 18–99 - NCT03481283Recruiting
Testing amylin’s role in nerve pain from type 2 diabetes
This study looks at whether amylin is involved in nerve damage causing pain or numbness in the feet or hands for people with type 2 diabetes. If you qualify, you may be evaluated with nerve testing to see how your nerve function compares to the study’s targets.
Lexington, KentuckyAges 18 years+ - NCT03509064Recruiting
Study of quality of life in Sjögren nerve pain
This trial looks at people with Sjögren who may have small-fiber nerve problems that can cause pain, temperature-related nerve symptoms, or body-function nerve issues. It aims to understand how these nerve problems affect quality of life and medical needs, and compare them with people without neuropathy.
ParisAges 18 years+ - NCT03881930Recruiting
Balance therapy tailored with changed visual cues for neuropathy
This study tests a balance-retraining program that uses modified visual information to help people with neuropathy feel steadier while walking. You may benefit if your balance problems are linked to nerve-related sensitivity and you can safely participate in walking and standing exercises.
ParisAges 18 years+ - NCT03920774Recruiting
Study of Familial Dysautonomia in People With IKBKAP Changes
This study looks at how familial dysautonomia (FD) progresses over time in people who have a confirmed IKBKAP genetic change. It may help doctors better understand the condition and plan future treatments.
New York, New YorkAges 4 years+ - NCT04208828Recruiting
IVIG for difficult gastrointestinal auto-immune nerve symptoms
This trial tests intravenous immunoglobulin (IVIG), a donated antibody treatment, for people whose gastrointestinal (GI) “motor” symptoms are not improving with standard care and may be auto-immune related. If you’re eligible, IVIG could help calm the immune system and improve gut movement symptoms.
Louisville, KentuckyAges 12–90 - NCT04299893RecruitingPhase 2/Phase 3
Ozone treatment for chemotherapy nerve pain
This trial tests whether ozone therapy can reduce painful nerve damage caused by chemotherapy. It is for adults with ongoing moderate-to-severe pain in the hands or feet after chemotherapy.
Las Palmas de Gran Canaria, Las PalmasAges 18–100 - NCT04678895RecruitingPhase 2
Low-dose naltrexone for nerve pain from diabetes
This Phase 2 trial studies whether a low dose of naltrexone can reduce painful nerve pain caused by diabetes. It may help people whose diabetic nerve pain did not improve with at least one standard treatment.
Lebanon, New HampshireAges 18 years+ - NCT04687215Recruiting
Spinal cord stimulation for painful diabetic nerve pain
This trial studies whether a spinal cord stimulator can reduce pain from diabetic nerve damage in the legs. It focuses on people with long-lasting type 2 diabetes and significant, treatment-resistant pain.
Chicago, IllinoisAges 18 years+ - NCT04699734Recruiting
Nerve block for nerve pain from diabetes
This trial studies whether a numbing “nerve block” can reduce long-lasting nerve pain caused by diabetic neuropathy. You may keep your usual pain medicines, and the study will mainly check whether you fit the safety and diagnosis criteria.
Aarhus N, JutlandAges 18 years+ - NCT04759443Recruiting
Skin testing to detect small-fiber nerve damage
This study looks for small-fiber neuropathy (nerve damage that can affect pain and sensation) by examining skin properties. It may help researchers find easier ways to detect this condition using skin-based testing.
Boston, MassachusettsAges 18 years+ - NCT04912843RecruitingPhase 2/Phase 3
Gene therapy for inherited optic nerve vision loss
This trial tests a gene therapy injection into the eye to improve vision in people with a specific type of inherited optic nerve disease called Leber’s hereditary optic neuropathy (LHON). It is aimed at people who have a particular genetic change and a history of vision loss lasting long enough to measure change, while checking for safety first.
BeijingAges 12–75 - NCT04970121RecruitingPhase 2
Duloxetine for chemotherapy nerve pain in solid tumor patients
This Phase 2 trial tests duloxetine to see if it safely reduces painful nerve damage caused by chemotherapy (especially taxanes) in people with solid tumors. If you have moderate-to-severe nerve pain and meet lab and heart-safety checks, this study may be an option.
Bengbu, AnhuiAges 18–75 - NCT05577390Recruiting
Comparing two treatments for diabetic nerve pain
This study compares two approaches to treating nerve pain caused by diabetes. You may be eligible if your diabetic neuropathy is moderate to severe and you can reliably use a phone for study steps.
Loma Linda, CaliforniaAges 45–85 - NCT05624138RecruitingPhase 3
Ketotifen to help prevent nerve damage from oxaliplatin
This trial tests whether ketotifen can protect against nerve damage (called peripheral neuropathy) caused by oxaliplatin, a common chemotherapy used for stage III colon cancer. If it works, it may help reduce tingling, numbness, or burning pain in the hands and feet.
Tanta, OtherAges 18 years+ - NCT05749094Recruiting
Ultrasound of the optic nerve in new suspected giant eye artery disease
This trial studies whether a quick ultrasound of the optic nerve (plus an eye exam) can help evaluate new suspected giant cell arteritis (GCA). It may help doctors assess eye risk early and decide on the best next steps.
London, OntarioAges 50–99 - NCT05904340Recruiting
Acupuncture-like electrical stimulation for nerve pain after chemo
This trial studies whether a skin-applied, acupuncture-like electrical treatment can reduce ongoing nerve pain (chemotherapy-induced peripheral neuropathy) after breast cancer chemotherapy. It may help if your nerve symptoms have not improved after finishing chemo.
Changhua, ChanghuaAges 18–80 - NCT05928429Recruiting
Cold treatment to prevent nerve pain from weekly paclitaxel
This trial tests whether cryotherapy (cooling the hands/feet during chemo) can prevent or lessen nerve pain caused by paclitaxel in people with early breast cancer. It may help you stay more comfortable and function better during treatment.
CopenhagenAges 18 years+ - NCT06128720Recruiting
Hyperbaric oxygen therapy for optic nerve damage
This study tests if breathing pure oxygen in a pressurized chamber (hyperbaric oxygen therapy) can help people with optic neuropathy, a condition that damages the nerve connecting the eye to the brain.
Palo Alto, CaliforniaAges 18 years+ - NCT06461377RecruitingPhase 4
GLP-1RA for heart nerve damage in type 2 diabetes
This trial tests whether a type of diabetes medicine called GLP-1RA can help prevent or improve nerve damage in the heart caused by diabetes. It is for people with type 2 diabetes who are overweight or obese.
Nanjing, JiangsuAges 18–70 - NCT06480786Recruiting
Spinal cord stimulator for diabetic nerve and artery pain
This study tests if a spinal cord stimulator (a device that sends mild electrical pulses to the spine) can relieve severe leg pain caused by diabetic nerve damage and poor blood flow. It may help people who have not found enough relief from other treatments.
Omaha, NebraskaAges 19–89 - NCT06488963Recruiting
Cold therapy for nerve pain in kids on vincristine
This study tests if applying cold to hands and feet can help prevent or reduce nerve damage (peripheral neuropathy) caused by the chemotherapy drug vincristine in children and teens. It's for patients aged 7-18 who are newly diagnosed and getting their first round of treatment.
IstanbulAges 7–18 - NCT06500728Recruiting
Vision involvement in giant cell arteritis
This study looks at how vision is affected in people with giant cell arteritis (GCA) -- a condition where blood vessels become inflamed. It compares those with GCA-related vision loss to people who have similar vision problems but not from GCA, to better understand and treat these eye issues.
Milan, LombardyAges 18 years+
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Common questions
- Are there clinical trials for neuropathy?
- Yes. Clin2 currently lists 274 recruiting neuropathy studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a neuropathy trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a neuropathy trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.