Clinical trials
Peripheral Neuropathy With Type 2 Diabetes clinical trials
Below are recruiting peripheral neuropathy with type 2 diabetes clinical trials, each written for real people, not researchers. We’re tracking 69 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06619860RecruitingPhase 2
VX-993 for diabetic nerve pain
This trial tests a new medicine called VX-993 for people with diabetes who have had nerve pain in both feet or legs for at least a year. The goal is to see if it reduces pain and is safe.
Cullman, AlabamaAges 18–80 - NCT06544876Recruiting
Balance and recovery in diabetes nerve damage
This study looks at how diabetes-related nerve damage affects balance and the ability to recover from a stumble. It may help find better ways to prevent falls.
Austin, TexasAges 50–99 - NCT07708233RecruitingPhase 4
Benfotiamine vs vitamin B complex for diabetic nerve pain
This study compares two types of vitamin B supplements to see which one better relieves nerve pain and numbness in people with diabetes. It may help if you have diabetic neuropathy and are looking for a safe, non-drug option.
Pathumthani, BangkokAges 18 years+ - NCT06628908RecruitingPhase 3
Study of suzetrigine for painful diabetic nerve damage
This trial tests an experimental medicine called suzetrigine to see if it can safely reduce pain caused by nerve damage from diabetes (diabetic peripheral neuropathy). It might be an option if you have had daily pain in both legs and current treatments haven't worked well enough.
Anniston, AlabamaAges 18–80 - NCT07231419RecruitingPhase 3
Study of suzetrigine for diabetic nerve pain
This trial tests an experimental pain drug called suzetrigine for people with diabetic peripheral neuropathy (nerve damage from diabetes that causes pain in the feet and legs). It aims to see if the drug can safely reduce pain over time.
Birmingham, AlabamaAges 18–80 - NCT07183761RecruitingPhase 2
Stem cell therapy for diabetic nerve pain
This study tests whether umbilical cord stem cells can help people with diabetic nerve damage in their legs who haven't gotten enough relief from standard treatments. It aims to improve symptoms like numbness, pain, and tingling.
Chongqing, Chongqing MunicipalityAges 18–80 - NCT07028528RecruitingPhase 2
Study of Levagen+ for diabetic nerve pain
This trial tests if Levagen+ (a supplement) can reduce nerve pain caused by diabetes. It is for people with type 1 or type 2 diabetes who have significant nerve pain in their feet or legs.
Fortitude Valley, QueenslandAges 18–75 - NCT07036796RecruitingPhase 2
Melatonin for diabetic nerve pain
This trial tests whether melatonin can help relieve pain and discomfort from diabetic peripheral neuropathy (nerve damage caused by diabetes). If you have type 2 diabetes with nerve pain and are on stable diabetes medications, you may be eligible.
CairoAges 40–75 - NCT07712913RecruitingPhase 3
Pregabalin for nerve pain from diabetes or shingles
This trial tests an extended-release version of pregabalin (a pain medication) for people with long-term nerve pain caused by diabetes or shingles. It aims to see if this once-daily pill can reduce pain with fewer side effects.
Salvador, Estado de BahiaAges 18–75 - NCT05950659Recruiting
Wearable insoles to prevent repeat diabetic foot ulcers
This trial tests special sensory insoles (called Orpyx Sensory Insoles) to help prevent diabetic foot ulcers from coming back. It aims to reduce high-pressure foot spots for people who already had a healed nerve-related ulcer.
Baltimore, MarylandAges 18 years+ - NCT04257877Recruiting
Studying blood proteins in children with type 1 diabetes
This study looks at blood protein patterns in children with type 1 diabetes to better understand the condition. It may help researchers find markers linked to how diabetes is doing, especially in young, early-stage children.
ThessalonikiAges 5–10 - NCT04442451Recruiting
Study how fatigue happens in prediabetes and type 2 diabetes
This study looks at why people with prediabetes or type 2 diabetes may feel unusually tired during activities. You may be asked to do exercise testing and answer questions to help researchers understand the body changes behind fatigue.
Ann Arbor, MichiganAges 30–85 - NCT04791371Recruiting
Study how fitness and insulin resistance relate to diabetes
This study looks at how low physical activity, insulin resistance in small blood vessels, and cardiorespiratory fitness connect to diabetes and blood sugar control. You may be eligible if you are generally sedentary and fit within the weight range, and if you do not have certain heart, lung, nerve, or medication factors.
Aurora, ColoradoAges 30–55 - NCT05363761RecruitingPhase 1
Artery procedure to treat type 2 diabetes and related problems
This Phase 1 study tests a new artery “ablation” procedure for people with type 2 diabetes, aiming to improve diabetes and related conditions like high blood pressure. It will also check whether the procedure is safe and works well enough to study further.
Panama CityAges 21–65 - NCT05369065RecruitingPhase 1
Artery ablation for type 2 diabetes with kidney and liver arteries
This Phase 1 study tests whether a minimally invasive artery procedure can improve type 2 diabetes and related health problems by targeting kidney and liver blood vessels. Because it’s early-stage, the main goal is safety and learning how the treatment works in people who meet specific diabetes, blood pressure, and blood test requirements.
TbilisiAges 21–65 - NCT05577390Recruiting
Comparing two treatments for diabetic nerve pain
This study compares two approaches to treating nerve pain caused by diabetes. You may be eligible if your diabetic neuropathy is moderate to severe and you can reliably use a phone for study steps.
Loma Linda, CaliforniaAges 45–85 - NCT05633810RecruitingPhase 3
Testing colchicine plus coated aspirin to prevent heart events
This Phase 3 study tests whether colchicine and a special type of aspirin can lower the risk of future heart attacks, strokes, or other major heart problems in people with type 2 diabetes who have not had a prior heart event. It aims to reduce cardiovascular risk using medicines that may calm inflammation and protect blood vessels.
Bentley, Western AustraliaAges 55–80 - NCT06124586Recruiting
Early angioplasty for diabetic foot ulcers
This trial tests if an early procedure to open blocked leg arteries (angioplasty) helps heal foot ulcers in people with type 2 diabetes. It aims to improve blood flow and prevent amputation.
DüsseldorfAges 18 years+ - NCT06480786Recruiting
Spinal cord stimulator for diabetic nerve and artery pain
This study tests if a spinal cord stimulator (a device that sends mild electrical pulses to the spine) can relieve severe leg pain caused by diabetic nerve damage and poor blood flow. It may help people who have not found enough relief from other treatments.
Omaha, NebraskaAges 19–89 - NCT07693296Recruiting
Walking for diabetes: a downhill aerobic exercise study
This study tests if downhill walking on a treadmill can help people with type 2 diabetes manage their blood sugar better. If you have stable diabetes and can walk on a treadmill, this might be a good option for you.
Istanbul, MaltepeAges 18–65 - NCT06519942Recruiting
Muscle and bone health in diabetes with nerve damage
This study looks at how diabetes and nerve damage affect your muscles and bones. It compares people with type 2 diabetes to healthy volunteers to learn more about these changes.
GhentAges 40–70 - NCT06567795Recruiting
Monitoring heart risk with a wearable sensor in diabetes
This trial tests a wearable chest sensor (called HEMOTAG) to monitor heart events in people with long-standing Type 2 diabetes who also have heart disease or specific diabetes-related complications. The sensor is worn at home for short periods to catch early signs of heart trouble, aiming to improve personalized care.
West Palm Beach, FloridaAges 40 years+ - NCT06568185RecruitingPhase 2
Alpha lipoic acid and vitamin B for diabetic nerve damage
This trial tests whether a combination of alpha lipoic acid (a natural antioxidant) and vitamin B supplements can help relieve nerve pain, numbness, or tingling caused by diabetes. It is for people with type 2 diabetes who have diabetic nerve damage.
Kubang Kerian, KelantanAges 18 years+ - NCT07690163Recruiting
Diabetes blood sugar check in newly diagnosed patients
This trial is checking how well blood sugar is controlled in adults recently diagnosed with type 2 diabetes (within the last 3 months). It aims to see if current treatments or lifestyle changes are working and may help guide future care.
KyivAges 18 years+
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Common questions
- Are there clinical trials for peripheral neuropathy with type 2 diabetes?
- Yes. Clin2 currently lists 69 recruiting peripheral neuropathy with type 2 diabetes studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a peripheral neuropathy with type 2 diabetes trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a peripheral neuropathy with type 2 diabetes trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.