Clinical trials
Non-metastatic Breast Cancer clinical trials
Below are recruiting non-metastatic breast cancer clinical trials, each written for real people, not researchers. We’re tracking 84 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07877376Recruiting
How thinking problems affect pain in breast cancer survivors
This study looks at whether mild memory or thinking issues after breast cancer treatment are linked to ongoing pain. If you join, you will help doctors understand this connection, which may lead to better pain care.
Boulogne-Billancourt, IDEAges 35–65 - NCT03784651Recruiting
How breast cancer treatment changes metabolism and bone
This study looks at how standard breast cancer treatments affect your body’s metabolism and bones in postmenopausal people with early-stage breast cancer. It may help doctors better predict and prevent bone and metabolic side effects from treatment.
Copenhagen, DanmarkAges 50–70 - NCT07699991Recruiting
Support program for breast cancer survivors
This study tests a navigation program to help breast cancer survivors get the support services they need after treatment. It is designed for people treated at the Stefanie Spielman Breast Center who may face extra barriers, such as being older, Black, Hispanic, or living in a rural area.
Columbus, OhioAges 18 years+ - NCT06679387RecruitingPhase 2
Memantine to prevent paclitaxel nerve damage in breast cancer
This trial tests whether the drug memantine can help prevent or reduce nerve pain and other side effects caused by the chemotherapy drug paclitaxel in breast cancer patients. If you are about to start weekly paclitaxel, this study may offer extra protection to your nerves.
CairoAges 18 years+ - NCT07471776RecruitingPhase 2
Predicting ADC treatment response with PET scans in advanced breast cancer
This study uses special PET scans to see if a type of targeted therapy called an anti-TROP2 ADC will work well for your advanced breast cancer. The therapy is already part of your standard care; the scans help doctors understand how your tumor responds.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06324721Recruiting
Understanding arm swelling after breast cancer treatment
This study looks at why some people feel arm swelling (lymphedema) after breast cancer treatment even when tests don't show swelling. It follows people who are about to have breast surgery with lymph node removal and checks how they feel over time.
Leuven, Vlaams-BrabantAges 18 years+ - NCT07389967Recruiting
Nutrition awareness study for women after breast cancer treatment
This study looks at how aware women are about nutrition after finishing their main breast cancer treatment. It aims to help improve support for diet and healthy eating habits.
Chapel Hill, North CarolinaAges 18 years+ - NCT07376174Recruiting
HER2-positive breast cancer and dual-target therapy study
This study looks at how well a combination of two targeted drugs (trastuzumab and pertuzumab) works for people with HER2-positive breast cancer that hasn't spread. It aims to understand how HER2 levels affect treatment outcomes after surgery.
Jinan, ShandongAges 18 years+ - NCT07326800Recruiting
Meditation and values program for breast cancer patients
This trial tests a program called MAEva that combines meditation and acceptance techniques to help patients with non-metastatic breast cancer. It aims to improve well-being by focusing on personal values and coping skills.
Vandœuvre-lès-NancyAges 18 years+ - NCT07297134Recruiting
PTEN and Organ-Specific microRNAs in Breast Cancer
This trial looks at specific molecules (PTEN and microRNAs) in the blood to see if they help doctors understand how breast cancer spreads. If you have breast cancer (whether it has spread or not) or are healthy, you might be eligible.
Istanbul, IstanbulAges 18 years+ - NCT05485766RecruitingPhase 2
Pembrolizumab with cancer medicines for BRCA-mutated triple negative breast cancer
This Phase 2 trial studies a treatment plan given before surgery (neoadjuvant) and after surgery (adjuvant) for people with BRCA1/2-mutated triple negative breast cancer that has not spread. It aims to improve how well the cancer responds and how long people stay cancer-free.
Gifu, GifuAges 18 years+ - NCT06225284RecruitingPhase 2
Chemotherapy with or without hormone drug for premenopausal TNBC
This trial tests whether adding a hormone-blocking drug (GnRH agonist) to standard chemotherapy before surgery helps premenopausal women with triple-negative breast cancer. It aims to improve treatment outcomes by targeting hormones that may fuel tumor growth.
TaipeiAges 18 years+ - NCT07166185Recruiting
Targeted therapy before surgery for HER2+ breast cancer
This trial tests a combination of two targeted drugs (trastuzumab and pertuzumab) given as a shot under the skin before surgery for women with a specific type of breast cancer called HER2-positive. The goal is to see if this treatment works well for women in Algeria.
BlidaAges 19 years+ - NCT07162675Recruiting
Step count and treatment response in breast cancer patients
This study looks at how your daily step count, measured by a smartwatch, relates to how well your breast cancer responds to treatment before surgery. It may help show if being more active during chemotherapy leads to better outcomes.
Ankara, YenimahalleAges 18 years+ - NCT07140107Enrolling by invitation
Comparing original vs. AI-made plain language summaries
This trial tests if an AI-generated plain language summary is as good as a human-written one for women with breast cancer. It compares how patients understand information about their treatment options.
SplitAges 18 years+ - NCT07107594Recruiting
Exercise, nutrition and support program for early breast cancer
This trial tests a program combining physical exercise, psychological support and nutritional advice before chemotherapy to see if it can improve treatment response in early breast cancer patients.
BarcelonaAges 18 years+ - NCT07049133Recruiting
Tracking side effects of T-DXd for advanced breast cancer
This study looks at people with advanced breast cancer who will receive a drug called T-DXd. Researchers want to understand the side effects of this treatment by analyzing blood samples.
MilanAges 18 years+ - NCT06911970Recruiting
Exercise and immune response in cancer treatment
This trial tests whether aerobic exercise can help your immune system fight cancer better during chemotherapy or immunotherapy. It is for people with breast or colon cancer that has not spread to other parts of the body.
Sherbrooke, QuebecAges 40–70 - NCT06914440RecruitingPhase 2
Radiation and immunotherapy before surgery for HR+/HER2- breast cancer
This trial is testing a new treatment approach for patients with a certain type of breast cancer (HR+/HER2-). It combines radiation therapy with chemotherapy and an immunotherapy drug before the patient's main surgery, to see if it can shrink or eliminate the tumor more effectively.
Xi'an, Shannxi ProvinceAges 18–75 - NCT05396612Recruiting
Studying the immune response in non-cancer-spread breast surgery
This study looks at how your immune system changes while you receive standard breast cancer treatment around the time of surgery. The goal is to learn why some people respond better than others, which could help future treatment choices.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06807502Recruiting
Blood test for breast cancer follow-up
This trial uses a simple blood test (ScreenCell device) to look for circulating tumor cells (CTCs) in women. It aims to see if CTCs help monitor breast cancer during follow-up, including for those with metastatic or newly diagnosed breast cancer, as well as healthy volunteers.
Neuilly-sur-SeineAges 18 years+ - NCT06797635RecruitingPhase 2
Study of Patritumab Deruxtecan and Pembrolizumab for High-Risk Early Breast Cancer
This trial tests a combination of targeted therapies (patritumab deruxtecan plus pembrolizumab) along with other anticancer drugs for people with a high-risk type of early-stage breast cancer that is either triple-negative or has very low hormone receptors and is HER2-negative. The goal is to see if this approach can help prevent the cancer from coming back.
Santa Monica, CaliforniaAges 18 years+ - NCT06748222RecruitingPhase 3
Online mindfulness program for breast cancer survivors
This trial tests a 6-week online mindfulness program to help breast cancer survivors manage mild to moderate depression. You may qualify if you finished active treatment within the last 5 years and can use a digital device.
Phoenix, ArizonaAges 18–50 - NCT06681064Recruiting
Tracking breast cancer changes during pre-surgery treatment
This study looks at how breast cancer changes while you are receiving chemotherapy or targeted therapy before surgery. The goal is to better understand which treatments work best for different types of breast cancer.
LondonAges 18 years+
Hear when a new Non-metastatic Breast Cancer trial opens
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Common questions
- Are there clinical trials for non-metastatic breast cancer?
- Yes. Clin2 currently lists 84 recruiting non-metastatic breast cancer studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a non-metastatic breast cancer trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a non-metastatic breast cancer trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Breast Cancer Early Stage Breast Cancer (Stage 1-3)
- Metastatic Non-squamous Non Small Cell Lung Cancer
- Breast Cancer (Triple Negative Breast Cancer (TNBC))
- Metastatic Breast Cancer
- Non Small Cell Lung Cancer Metastatic
- Non Small Cell Lung Cancer
- Locally Advanced or Metastatic Breast Cancer
- Non-squamous Non-small Cell Lung Cancer
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.