Clinical trials
Obesity & Overweight clinical trials
Below are recruiting obesity & overweight clinical trials, each written for real people, not researchers. We’re tracking 486 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07440147Recruiting
Akkermansia and Berberine for night shift workers' insulin sensitivity
This trial tests whether taking a probiotic called Akkermansia muciniphila and a natural plant compound called berberine can improve how your body uses insulin. If you work night shifts regularly, this study may help you find a way to support your metabolic health.
Graz, StyriaAges 21 years+ - NCT07443059RecruitingPhase 1
Zovaglutide study in people with kidney problems
This study tests an investigational drug called Zovaglutide (ZT002) in people with different levels of kidney function, from normal to severely impaired. The goal is to see how the drug is processed by the body and how safe it is for people with kidney problems.
Xiamen, FujianAges 18–75 - NCT07446595Recruiting
Diet and exercise program for adult cancer survivors
This study tests a program to help cancer survivors improve their diet and exercise habits. You will get group support, one-on-one coaching with a dietitian, and supervised exercise sessions for 6 months. It might help you feel better and lower your risk of other health problems.
Aurora, ColoradoAges 18–75 - NCT07447362Recruiting
Managing heart health risks in adults
This study checks if a program to manage heart health risks works better than usual care. If you have a risk factor like high blood pressure, diabetes, or smoking, you may qualify.
Santiago, Santiago MetropolitanAges 18 years+ - NCT07457437Recruiting
Exercise and medication for weight loss in women
This study tests whether adding resistance exercise to a new weight-loss medication helps women preserve muscle while losing weight. It may be an option for women who want to protect their muscle mass during treatment.
Exeter, DevonAges 25–50 - NCT07469800RecruitingPhase 3
IBI362 for high blood pressure in overweight adults
This study tests an injectable medicine (IBI362) to see if it helps lower blood pressure in people who are overweight or have obesity. You may be eligible if you have high blood pressure but are not currently taking medication for it, and you do not have diabetes or major heart problems.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07470749Recruiting
Study of fatty liver and nutrition in rural Bangladesh
This study looks at metabolic fatty liver disease (MAFLD) in adults living in a rural area of Bangladesh. It aims to understand how diet and metabolic risk factors like blood sugar or cholesterol relate to the condition, which may help in finding better ways to prevent or manage it.
DhakaAges 18 years+ - NCT07672821Recruiting
Time-restricted eating after weight-loss surgery
This study tests if time-restricted eating (eating only during a set window of hours each day) helps people who have had weight-loss surgery but either didn't lose enough weight or regained weight after surgery. It also includes people with obesity who haven't had surgery.
Bursa, Lütfen Seçiniz.Ages 18–65 - NCT07571109RecruitingPhase 3
Weight Loss Medicine for Sleep Apnea on CPAP
This study tests a new injectable medicine (NNC0487-0111) to help people lose weight and improve obstructive sleep apnea (a breathing condition during sleep). You must already be using a CPAP machine (positive airway pressure device) for your sleep apnea.
Gilbert, ArizonaAges 18 years+ - NCT07495020Recruiting
Weight loss surgery study for type 2 diabetes
This study tests a new type of weight loss surgery for people with type 2 diabetes and a body mass index (BMI) between 25 and 35. The surgery uses a clip and a special stitch to help with weight loss and diabetes control.
AstanaAges 18–65 - NCT07506369Recruiting
How pancreatic polypeptide affects appetite fullness in healthy men
This study tests whether pancreatic polypeptide (a natural hormone) changes how full you feel when combined with another hormone called amylin. It may help us understand appetite control in healthy people.
Hellerup, Capital RegionAges 18–65 - NCT07509307RecruitingPhase 3
Study of a new medicine for weight loss and knee pain in osteoarthritis
This trial tests if a new medicine, NNC0487-0111, can help people with excess weight and knee osteoarthritis lose weight and reduce knee pain. It is for people who have had knee pain for at least three months and who can stop taking pain relievers for short periods before study visits.
Escondido, CaliforniaAges 18 years+ - NCT07519980Recruiting
Xanthigen supplement for weight and metabolism in young adults
This study tests whether a supplement called Xanthigen can help people aged 20–50 with mild overweight lose weight and improve their metabolism. You'll take the supplement and have your weight, blood work, and overall health monitored over time.
Murcia, MurciaAges 20–50 - NCT07520929Recruiting
How Sauna Sessions Affect Blood Sugar Control
This study tests whether spending time in a sauna can help your body control blood sugar levels. You'll visit a lab twice to try a sauna session and have your blood sugar measured, which could help researchers understand if heat therapy benefits people with weight or metabolism concerns.
Charlottetown, Prince Edward IslandAges 30–55 - NCT07525791RecruitingPhase 1
New Weight-Loss Drug Study With Birth Control Pills
This study tests how a new experimental medication (NNC0662-0419) works in women with excess weight who cannot become pregnant. Researchers will also check how it interacts with birth control pills and affects stomach emptying.
Overland Park, KansasAges 18–64 - NCT07533175RecruitingPhase 3
Testing a new weight-loss medicine for type 2 diabetes
This study tests whether a new medicine called NNC0487-0111 helps people with type 2 diabetes and excess weight lose weight. You'll take the medicine along with your current diabetes care to see if it works better than standard treatment.
Birmingham, AlabamaAges 18 years+ - NCT07571005RecruitingPhase 3
Testing a New Weight-Loss Medicine for Sleep Apnea
This study tests whether a new injectable medicine called NNC0487-0111 helps people with excess weight and moderate-to-severe obstructive sleep apnea (a condition where breathing stops repeatedly during sleep) lose weight and improve their sleep apnea—without needing a CPAP machine. The goal is to see if better weight loss can reduce sleep apnea symptoms.
San Diego, CaliforniaAges 18 years+ - NCT07577765Recruiting
Keeping Weight Off With a Personalized Plan
This study tests a customized approach to help you maintain weight loss you've already achieved. Researchers will use your smartphone to send you tailored support and track your progress over time.
Salt Lake City, UtahAges 18–65 - NCT07583459Recruiting
Summer childcare program to prevent unhealthy weight gain in preschoolers
This study tests whether a center-based childcare program during summer can help prevent excessive weight gain in preschool-aged children from low-income families. The program focuses on healthy eating and activity habits during the summer months when children are not in school.
Columbia, South CarolinaAges 3–5 - NCT07605169Recruiting
Long-Term Health Effects of Lifestyle Changes
This study follows people who already completed a lifestyle intervention program to see how diet and exercise changes affect their health and well-being over time. Researchers want to understand if these changes have lasting benefits.
Gothenburg, Västra Götaland CountyAges 45–65 - NCT07607587RecruitingPhase 1
Testing a new weight-loss drug for people who couldn't tolerate GLP-1 shots
This study tests a new injectable medication called cagrilintide for people with obesity who had to stop GLP-1 drugs (like Ozempic or Wegovy) because of stomach problems. The goal is to see if cagrilintide causes fewer stomach side effects while still helping with weight.
Walnut Creek, CaliforniaAges 18 years+ - NCT07627074Recruiting
Real-world weight loss study with semaglutide
This study tracks how semaglutide (an injectable medication that reduces appetite) helps adults lose weight in everyday life. Researchers want to understand how well it works and how safe it is for people starting the treatment.
Seattle, WashingtonAges 18 years+ - NCT07630597Recruiting
Ear Nerve Stimulation to Help Weight Loss
This trial tests a non-invasive device that gently stimulates a nerve in your ear to help you lose weight after lifestyle changes haven't worked well enough. You wear the device on your ear for 12 weeks while continuing healthy habits.
Nanjing, JiangsuAges 18–50 - NCT07652047RecruitingPhase 1
Safety Study of CX11 Tablets for Weight Management
This study tests whether a new medication called CX11 is safe and well-tolerated at different doses in people with overweight or obesity. The goal is to understand how the body responds to the drug before larger trials test whether it helps with weight loss.
Las Vegas, NevadaAges 18–55
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Common questions
- Are there clinical trials for obesity & overweight?
- Yes. Clin2 currently lists 486 recruiting obesity & overweight studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a obesity & overweight trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a obesity & overweight trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.