Clinical trials
Obesity clinical trials
Excess body weight that increases the risk of many other health conditions. We’re tracking 1,500 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05747976Recruiting
Study for children with very high body size measurements
This study is building a program database for children who have unusually high body size measurements for their age. By collecting genetic and health information, researchers hope to better understand causes of obesity and guide care.
Houston, TexasAges Any age - NCT05753124Recruiting
How weight, diabetes, and bariatric surgery affect pregnancy
This study looks at how weight, blood-sugar problems, and past weight-loss surgery affect pregnancy outcomes. You may be able to help researchers understand what to expect and how to plan care during pregnancy.
LondonAges 18–50 - NCT05754645Recruiting
Study of gut microbiome in weight-related pregnancy outcomes
This study looks at differences in the gut’s living microbes (microbiome) in people who are trying to conceive or are early in pregnancy, and how that may relate to pregnancy outcomes. It may help researchers understand whether microbiome changes are linked to healthier—or more complicated—pregnancies.
Rotterdam, South HollandAges 18–45 - NCT05759637Recruiting
Tests treatments for diabetes, weight, and high cortisol levels
This trial studies people who have type 2 diabetes and excess body weight, looking at how high cortisol (a stress hormone) may be involved. If you qualify, you may get a study treatment designed to improve diabetes and weight-related health by targeting cortisol-related pathways.
MilanAges 18–75 - NCT05772052Recruiting
Study taste and eating changes in adults with obesity
This trial looks at how eating patterns and taste perception differ in people with obesity. It may help researchers understand what influences appetite and taste, which could improve future treatments.
MilanAges 18–60 - NCT05798676Recruiting
Study of pregnancy factors linked to a child’s growth
This study looks at breastfeeding mothers and how a mother’s pregnancy and health factors may relate to a child’s growth and body fat. You might be able to join if you were normal weight or overweight/obese before pregnancy and you meet the pregnancy and delivery health requirements.
La Plata, Buenos AiresAges 18–40 - NCT05799222Recruiting
Nutrition program for obesity and diabetes risk
This trial tests a medically guided nutrition program to help improve weight and blood sugar in adults with obesity or early diabetes risk. It specifically targets people who meet income guidelines and don’t already use most diabetes or anti-obesity medicines.
Boston, MassachusettsAges 18–65 - NCT05804591RecruitingPhase 4
Pregabalin during weight-loss surgery to reduce pain
This trial tests whether pregabalin can help with pain control for people having laparoscopic sleeve gastrectomy (a weight-loss surgery). It may help reduce the discomfort around surgery and improve the overall recovery experience.
Warsaw, WarsawAges 18 years+ - NCT05844644RecruitingPhase 2
Golo plan for weight and blood sugar in prediabetes
This trial tests whether the Golo for Life plan (with a release supplement) can improve blood sugar and help with weight in adults who have prediabetes or type 2 diabetes. If you join, you’ll follow the program and attend clinic visits while your health, diet, and weight are tracked.
LaSalle, OntarioAges 18–75 - NCT05857150Recruiting
Study tests exercise effects in adults with obesity
This study looks at how your body responds to exercise if you have obesity. It may help researchers understand which changes happen with exercise and how safe it is for people in your age group.
Rochester, MinnesotaAges 20–45 - NCT05859867Recruiting
Studying newborn and early-childhood community health
This study looks at how babies and young children (ages 0–5) in two local communities develop over time. It may help researchers understand community health needs and what supports work best for families.
NovaraAges 2 days–5 years - NCT05878912Recruiting
Obesity and weight loss in certain heart failure patients
This study looks at how higher body weight and weight loss affect people who have heart failure with preserved pumping strength. It uses heart scans to measure how the heart and body change, which may help guide future treatment plans.
OxfordAges 18–85 - NCT05906238Recruiting
Study to reduce harm from obesity stigma
This trial looks at ways to lessen the negative effects that people may experience from weight-related stigma. It’s meant to help improve well-being for people living with obesity.
Poitiers, VienneAges 18 years+ - NCT05908812Recruiting
Testing how blood sugar control links to a hormone in type 2 diabetes
This study looks at whether better blood sugar control changes levels of a hormone called irisin in people with type 2 diabetes and obesity, including those with or without age-related muscle loss (sarcopenia). Your results may help researchers understand the body’s response to diabetes and could guide future treatment ideas.
BariAges 60 years+ - NCT05912621RecruitingPhase 2
Tirzepatide for fat-related body dysfunction in overweight adults
This Phase 2 study tests whether tirzepatide can improve how your body handles fat (especially in people with overweight or obesity) and reduce fat-related “lipotoxicity.” It may help with body fat function and related health markers, but you must meet specific health and medication rules.
Palo Alto, CaliforniaAges 18–70 - NCT05917795Recruiting
Endoscopic stomach reduction for weight loss before kidney transplant
This trial tests an endoscopic procedure that helps reduce stomach size to support weight loss in people with severe kidney disease who may need a kidney transplant. It may help some patients meet transplant-center weight requirements and potentially improve readiness for transplant care.
RomeAges 18–70 - NCT05927519Recruiting
Compare a laryngoscope tool in obese vs nonobese men
This study compares how well a specific breathing tube placement tool (Airtraq) works in men who are obese versus men who are not, during planned surgeries. It may help improve the safety and ease of putting in a breathing tube.
IamitAges 18–80 - NCT05933499RecruitingPhase 2
Tirzepatide and bimagrumab for body fat and insulin sensitivity
This Phase 2 study tests two medicines to see how they change body fat, insulin sensitivity, and bone health in adults with obesity. It may help people who have tried lifestyle changes to lose weight but have not been able to, though diabetes and several health conditions must be ruled out first.
Boston, MassachusettsAges 18 years+ - NCT05935592Recruiting
Family phone tool to help kids at risk for weight gain
This study tests an interactive phone/tablet program for children and their parent or guardian, aiming to reduce the child’s risk of unhealthy weight gain. It may help by giving family-focused tips and support you can use at home.
New York, New YorkAges 8–12 - NCT05942287Recruiting
Weight and weight loss study in heart failure with weak pumping
This study looks at how obesity and weight loss affect people living with heart failure where the heart pumping strength is reduced. It uses heart imaging (MRI) to measure the heart and may help clarify what weight changes do for symptoms and heart function.
Jersey, JerseyAges 18–85 - NCT05945355Recruiting
Study of breathing training for children with asthma
This study looks at how an asthma-specific breathing training program affects children’s breathing and asthma control. It may help your care team understand who could benefit from inspiratory (breathing-in) training.
Durham, North CarolinaAges 6–17 - NCT05950620Recruiting
Weight management support in pediatric primary care visits
This trial studies how to bring weight management help into regular pediatric primary care. It may support children with obesity or ongoing unwanted weight gain through structured care during everyday clinic visits.
Portland, OregonAges 1 month–21 years - NCT05950698Recruiting
Study of obesity and bariatric surgery with mental and social factors
This study looks at how personal mental health and life circumstances relate to outcomes after bariatric (weight-loss) surgery. It may help the team understand what supports improve recovery and health after surgery.
Rio de Janeiro, Rio de Janeiro, BrazilAges 18–60 - NCT05962372Recruiting
Culturally tailored diet program for adults in Puerto Rico
This study tests a diet program designed to fit Puerto Rico culture and daily life. It may help adults with weight or blood sugar or blood fat concerns improve their health through regular check-ins.
San JuanAges 30–65
Hear when a new Obesity trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for obesity?
- Yes. Clin2 currently lists 1,500 recruiting obesity studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a obesity trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a obesity trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.