Clinical trials
Obesity clinical trials
Excess body weight that increases the risk of many other health conditions. We’re tracking 1,500 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06053645Recruiting
Weight and heart disease study
This study looks at how being overweight affects heart health. It tests a program that includes monthly check-ins and surveys, and is for people with a BMI of 30 or higher who also have a heart condition. The goal is to learn more about how to help people with both weight and heart concerns.
Rochester, MinnesotaAges 18 years+ - NCT06055036Recruiting
Stress reduction for heart health in Black men
This study looks at how reducing stress can improve cardiovascular health in Black men. It involves lifestyle changes and support to help lower your risk of heart disease.
Columbus, OhioAges 18 years+ - NCT06057597Recruiting
Comparing two types of gastric bypass surgery for weight loss
This trial compares a new version of gastric bypass (with a longer 150cm bypassed segment) to the standard Roux-en-Y gastric bypass to see which leads to better weight loss and health improvements. It is for people with severe obesity who are already scheduled for surgery and want to help find the best procedure.
ParisAges 18–65 - NCT06059651Recruiting
Bariatric Surgery and its Effects on Fat, Immune Cells, and Cancer
This study looks at how bariatric (weight-loss) surgery affects fat metabolism, immune cells, and cancer risk in women with severe obesity and high cholesterol. If you are a woman aged 35–60, White or Black, with a BMI of 40 or higher and high triglycerides or LDL, you may be eligible.
Baton Rouge, LouisianaAges 35–60 - NCT06061042Recruiting
Time-restricted eating for metabolic health
This study tests whether eating only during a specific time window each day can improve metabolic health in people with obesity and insulin resistance. If you have a high BMI and early signs of diabetes, this trial might help you understand a simple dietary change.
Amsterdam, North HollandAges 50–75 - NCT06063564Recruiting
Testing a digital tool to improve heart health in rural clinics
This study is testing a digital health app called PREVENT to help doctors and patients work together on heart-healthy habits like eating well and being active. It is designed for people in rural areas who want to lower their risk of heart disease.
St Louis, MissouriAges 18–64 - NCT06069622Recruiting
How a gene affects weight-loss treatment response
This study looks at how a weight-loss medication affects people with obesity who may have a specific gene difference (caveolin-1). It aims to understand why some people respond differently to GLP-1 treatments like semaglutide.
Boston, MassachusettsAges 18 years+ - NCT06076187Recruiting
How older adults digest protein after weight loss surgery
This study looks at how well older adults break down protein after bariatric surgery. It compares people who had surgery one to ten years ago with those who didn't, to understand protein needs.
Leuven, Flemish BrabantAges 18 years+ - NCT06098417Recruiting
Fatty liver markers before weight-loss surgery
This study looks at special markers in the blood to better understand and predict a fatty liver condition called NAFLD. It focuses on people who are very overweight and are already planning to have weight-loss surgery.
TriesteAges 18–65 - NCT06101693Recruiting
Biomarker study for suspected heart failure
This study looks at certain proteins in your blood to help doctors better understand and diagnose a type of heart failure called HFpEF. You might be able to join if your doctor recently ordered a blood test for NT-proBNP because they thought you might have heart failure.
GlasgowAges 18 years+ - NCT06105164Recruiting
Brain's Fullness Circuit Study
This study uses brain imaging and mild magnetic stimulation to explore how a brain circuit helps you feel full after eating. It may help us understand eating behaviors and weight regulation.
Belmont, MassachusettsAges 18–65 - NCT06105957Recruiting
Digital weight loss program for rural adults
This study tests a digital weight loss program designed for adults living in rural areas. It uses a smartphone app, website, and video group sessions to help you lose weight through diet and physical activity.
Columbia, South CarolinaAges 18 years+ - NCT06108128Recruiting
Food for thought: thinking skills and eating in children
This study looks at how children's thinking skills (like planning and self-control) affect their eating habits. It may help parents understand how to support healthy eating in young kids.
Philadelphia, PennsylvaniaAges 4–6 - NCT06111040Recruiting
Parenting study for food-driven young children
This study tests a program to help parents handle feeding their 4- or 5-year-old child who is very motivated by food. It aims to support healthy eating habits.
Philadelphia, PennsylvaniaAges 4–5 - NCT06116149Recruiting
Healthy lifestyle program for new mothers in WIC clinics
This trial tests a lifestyle program for new mothers (up to 1 year after giving birth) who have obesity or had gestational diabetes. It runs in WIC clinics and aims to help you improve your health after pregnancy.
New Orleans, LouisianaAges 18 years+ - NCT06116435Recruiting
Lifestyle program for weight loss and physical activity
This study tests a lifestyle program to help people become more active and lose weight. It compares different types of support to see what works best.
Aurora, ColoradoAges 18–65 - NCT06129110Recruiting
Weight loss and muscle fat study for adults aged 18-70
This study looks at how losing weight affects the fat that sits inside your muscles (called intermuscular fat). It might help people with overweight to better understand how weight loss can improve muscle health.
Aurora, ColoradoAges 18–70 - NCT06132477RecruitingPhase 4
Study of GLP-1 medicines after weight loss surgery
This study looks at what happens when people taking a GLP-1 medication (like Ozempic) either stop or continue it after weight loss surgery. The goal is to learn whether staying on the medicine helps with long-term weight control.
Columbia, MissouriAges 18 years+ - NCT06144593Recruiting
Carb cutting for people with type 2 diabetes
This study looks at whether cutting carbs on certain days can improve metabolism for people with type 2 diabetes. It may help if you have mild to moderate diabetes and are overweight or obese.
HvidovreAges 35–75 - NCT06151015Recruiting
Dietary nitrate and calorie restriction for brain health
This study tests whether eating foods rich in dietary nitrates (like beets) combined with reducing calorie intake improves memory and blood vessel function in older adults.
Nottingham, NottinghamshireAges 60–75 - NCT06153056Recruiting
Predicting success of stomach sleeve procedure
This study looks at factors that predict weight loss success after a non-surgical stomach reduction procedure (endoscopic sleeve gastroplasty). It may help if you have obesity-related health problems and have not succeeded with diet or lifestyle changes.
ParisAges 18 years+ - NCT06158594RecruitingPhase 2
Best Amount of Structure for Healthy Kids
This study looks at how much structure (like organized activities) is best for kids' health. It takes place over 14 months and involves filling out surveys and possibly wearing a device to track activity. Families who qualify may help researchers learn how to support healthy habits in children.
Columbia, South CarolinaAges 5–12 - NCT06169033Recruiting
Can belly fat scans predict weight-loss surgery success?
This study looks at how fat around your belly and inside your abdomen, seen on a CT scan, can predict how well bariatric (weight-loss) surgery will work for people with type 2 diabetes.
BeijingAges 16–70 - NCT06173778RecruitingPhase 2
Semaglutide for weight management after quitting smoking
This study tests whether the drug semaglutide (often used for weight loss) can help people who quit smoking avoid gaining weight. It's for people who are overweight or have weight-related health issues and want to stop smoking.
Austin, TexasAges 18–75
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Common questions
- Are there clinical trials for obesity?
- Yes. Clin2 currently lists 1,500 recruiting obesity studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a obesity trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a obesity trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.