Clinical trials
Obesity clinical trials
Excess body weight that increases the risk of many other health conditions. We’re tracking 1,500 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05935111Recruiting
Physical activity program for adults who can track activity
This study tests whether an online physical activity program is practical and doable for adults who meet certain health and tech access requirements. It may help you build a routine and see if you can stick with activity tracking using a wearable device and daily check-ins.
Binghamton, New YorkAges 18–64 - NCT05935826RecruitingPhase 3
Amino acids to reduce liver fat in teens with NAFLD
This study tests whether adding amino acids can lower fat stored in the liver of teens with non-alcoholic fatty liver disease (NAFLD). It may help improve liver health by changing how much liver fat is present over the study period.
Aurora, ColoradoAges 13–18 - NCT05950282Recruiting
Study of insulin sensitivity differences by age and PCOS status
This study looks at how well the body uses insulin (insulin sensitivity) across different ages, sexes, races, body weights, and whether someone has PCOS. It may help researchers understand why insulin function varies and how PCOS could be linked to metabolic health.
Houston, TexasAges 18 years+ - NCT05956574Recruiting
Lifestyle coaching program for weight and health changes
This study tests whether a lifestyle and activity program can help people with higher body weight make healthier changes. You may be asked to track your habits on a smartphone and participate in walking and exercise activities.
Augusta, GeorgiaAges 18–40 - NCT05958368Recruiting
Avocado study to improve blood sugar in type 2 diabetes
This study tests whether eating avocados can improve blood sugar control in adults with type 2 diabetes. You may have blood tests and will follow a specific eating plan while your diabetes care continues under your doctor.
Baton Rouge, LouisianaAges 18–65 - NCT05963971Recruiting
Bilingual online program to prevent weight gain in childhood leukemia
This trial tests a bilingual, online program to help children and teens who have ALL (a type of leukemia) stay at a healthy weight during the maintenance phase of treatment. It may help lower the chance of gaining too much weight while on chemotherapy.
New York, New YorkAges 5–21 - NCT05972564RecruitingPhase 1/Phase 2
SGLT2 drug trial for belly fat inflammation before weight-loss surgery
This early-phase trial tests whether an SGLT2 drug can reduce inflammation in belly fat and improve blood vessel function. It may help people with metabolic syndrome prepare for (and potentially benefit around) planned gastric bypass or sleeve surgery.
Nashville, TennesseeAges 18 years+ - NCT05975580RecruitingPhase 4
Medication plus lifestyle counseling for weight regain after bariatric surgery
This study looks at whether adding medication to lifestyle counseling can help people who have regained weight after sleeve gastrectomy or gastric bypass. It focuses on improving weight control and related health after surgery.
Orange, CaliforniaAges 18–70 - NCT05985486Recruiting
Lifestyle change for brain health in Down syndrome
This study looks at how a healthy lifestyle program can improve brain health in adults with Down syndrome who are overweight or obese. You will attend a medical center three times over a year for tests, and you'll need a caregiver to support you.
Kansas City, KansasAges 18–64 - NCT05986539Recruiting
Infant feeding and health study
This trial looks at how early feeding (breastmilk or formula) affects an infant's immune system and health. Researchers will collect samples and health information from mothers and their babies over time.
Moscow, IdahoAges 18 years+ - NCT05987631Recruiting
Predicting weight loss and health after weight loss surgery
This study looks at why some people lose more weight and improve their health more than others after bariatric surgery. It also has a subgroup that specifically studies people who are insulin resistant (a sign of prediabetes) to see how surgery affects their metabolism.
Gouda, South HollandAges 18–75 - NCT06003686Recruiting
Spinal cord injury education study for adults
This study is looking at how well a special education program helps people with spinal cord injuries manage their health and daily life after leaving the hospital. It is for adults who recently finished their first rehabilitation stay and have a spinal cord injury from the C5 level or lower.
Washington D.C., District of ColumbiaAges 18–70 - NCT06009276Recruiting
Gut bacteria, muscle blood flow, and fitness study
This study looks at how the bacteria in your gut affect blood flow to your muscles and your overall fitness. You will provide samples and do some exercise tests to help researchers understand this link.
Charlottesville, VirginiaAges 18 years+ - NCT06011499Recruiting
Online lifestyle program for prostate cancer survivors
This study tests an internet-based program to help prostate cancer survivors who are overweight and frail improve their health. You will be assigned to either a lifestyle coaching group or a usual care group, and both groups are followed for about 6 months.
Portland, OregonAges 18 years+ - NCT06015620Recruiting
Health changes after mini gastric bypass surgery
This study looks at how mini gastric bypass surgery helps with obesity-related health problems and changes in body composition. It aims to see if patients experience improvements in conditions like diabetes or high blood pressure.
Bhubaneswar, OdishaAges 18–65 - NCT06018636Recruiting
Diet and nutrition in early childhood growth
This study looks at how diet and nutrition affect young children's growth and development. It may help you learn more about feeding your child well.
Swat, Khyber PakhtunkhwaAges 1 day–2 years - NCT06019182Recruiting
MEHMO syndrome: Understanding the condition over time
This study follows people with or at risk for MEHMO syndrome over time to better understand the condition and identify biological markers. It may include both affected individuals and their family members to see how the condition runs in families.
Bethesda, MarylandAges 1 week–100 years - NCT06030362Recruiting
Probiotic study for weight and gut health in adults
This study tests whether taking a probiotic supplement can help with weight management and gut health in adults with overweight or obesity. You may be able to join if you are between 18 and 50, have a BMI of 25 to 40, and are generally healthy.
Los Angeles, CaliforniaAges 18–50 - NCT06032104Recruiting
Bean supplement study for colon cancer screening patients
This trial tests whether adding a daily bean supplement to your diet can improve colon health. You may be eligible if you are between 30 and 80, overweight, and scheduled for a routine colonoscopy.
Sacramento, CaliforniaAges 30–80 - NCT06039787Recruiting
Exercise and Brain Insulin Sensitivity Study
This study checks if exercise training changes how your brain responds to insulin. You will do ergometer (stationary bike) training, and your brain activity will be measured before and after. It's for people who are not very active now and want to see how exercise affects brain metabolism.
TübingenAges 20–65 - NCT06044571Recruiting
Weight loss program for older adults via telehealth
This trial tests a weight loss program delivered through video calls to help adults aged 65-85 with obesity lose weight. It is designed for those with at least two other health conditions and who are ready to make changes.
Chapel Hill, North CarolinaAges 65–85 - NCT06044935Recruiting
Nicotinamide riboside for fat burning and metabolism
This study tests whether a supplement called nicotinamide riboside (a form of vitamin B3) helps the body burn fat more efficiently during exercise. It may be a good option if you are overweight or have a specific type of diabetes (MODY2) and want to see if a natural supplement can boost your metabolism.
Bethesda, MarylandAges 18–65 - NCT06049420Recruiting
Lifestyle medicine for rural patients with chronic disease
This trial tests whether exercise therapy can help people with two or more chronic conditions like obesity, diabetes, or heart disease. It's designed for rural patients and requires a referral from your doctor.
Lewisburg, West VirginiaAges 18–64 - NCT06051591Recruiting
Food FARMacia: Helping families with food worries
This study tests a program called Food FARMacia to help families with young children who sometimes worry about having enough food. The goal is to see if the program can help prevent childhood obesity by providing support and resources.
Stanford, CaliforniaAges 6 months+
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Common questions
- Are there clinical trials for obesity?
- Yes. Clin2 currently lists 1,500 recruiting obesity studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a obesity trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a obesity trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.