Clinical trials
Older Adults clinical trials
Below are recruiting older adults clinical trials, each written for real people, not researchers. We’re tracking 526 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06027554RecruitingPhase 2
MitoQ for frailty, walking, memory, and blood flow in older adults
This trial tests whether a supplement called MitoQ can improve blood vessel health, walking speed, and thinking skills in older adults who are frail or have mild memory problems. It aims to see if MitoQ helps maintain independence and quality of life.
Farmington, ConnecticutAges 65–80 - NCT05988385Recruiting
Treating sleep apnea to protect memory in older adults
This study tests whether treating sleep apnea can help protect memory and brain health in older adults. It involves using a CPAP machine or other treatments for sleep apnea and may include memory tests and brain scans over 2 years.
Tucson, ArizonaAges 55–85 - NCT05972005Recruiting
At-home rehab for older adults after a hip fracture
This trial tests a support program for people age 55+ after a hip fracture, focusing on better recovery at home (or a retirement home). It may help improve outcomes after leaving the hospital by providing guidance and follow-up tailored to you.
Kingston, OntarioAges 55 years+ - NCT05963113Recruiting
Exercise and extra protein for swallowing and aging strength
This study tests whether a swallowing exercise program plus a higher-protein intake can improve function in older adults at risk for swallowing problems. It may help by strengthening muscles used for swallowing and supporting overall physical health.
New York, New YorkAges 65 years+ - NCT05955339Recruiting
Using visit recordings and open notes to improve care experience
This study tests two ways of sharing what happened at clinic visits—recording visits and using an “open notes” patient portal—to help older adults manage long-term health conditions with a better experience. It’s likely to help if you have multiple chronic conditions and can use email or a patient portal.
Manchester, New HampshireAges 18 years+ - NCT05912257Recruiting
Nutrition program before and after surgery to protect function
This study tests whether an “optimizing nutrition” plan before and after cancer surgery can help older adults maintain physical strength and daily functioning. You may be randomly assigned to the nutrition program or another study group, and you’ll be asked about diet and physical function.
Durham, North CarolinaAges 55 years+ - NCT05935241Recruiting
Program mPATH for sleep and activity in older adults
This trial tests a program (mPATH) to help older adults with sleep trouble by improving activity and exercise habits. It may be helpful if you have low income and want support building moderate exercise safely.
Baltimore, MarylandAges 65 years+ - NCT05906511RecruitingEarly Phase 1
Study how THC levels change in older adults
This early study measures how a THC dose (by mouth or vaporized form) moves through the body and how it affects the body’s responses. It mainly looks at safety and how THC behaves in older adults, including people who have used cannabis before.
West Haven, ConnecticutAges 65 years+ - NCT05886725Recruiting
At-home walking test to help recovery after major surgery
This study looks at how a simple at-home walking pattern test, done before and after major surgery, relates to how older adults recover. It may help doctors better understand recovery and possibly tailor support after surgery.
Chicago, IllinoisAges 60 years+ - NCT05830942Recruiting
Training walks plus brain stimulation for thinking skills in older adults
This study tests whether a structured walking exercise, combined with brain stimulation and brain scans, can improve or slow decline in thinking skills. It’s aimed at older adults who notice memory or confusion getting worse.
Gainesville, FloridaAges 65 years+ - NCT05820841RecruitingPhase 3
Acalabrutinib plus R-miniCHOP for untreated lymphoma in older adults
This study tests whether adding acalabrutinib to a reduced-strength chemotherapy plan (R-miniCHOP) works better and is safer for older adults with newly diagnosed diffuse large B-cell lymphoma. It may help you get a more effective treatment while using a dosing approach meant for people who may not tolerate full-strength therapy.
Homburg, SaarlandAges 61 years+ - NCT05822466Recruiting
Virtual Tai Chi program to help prevent falls
This study tests whether a virtual (online) Tai Chi–style exercise program can reduce falls in older adults. You may be eligible if you’ve fallen recently or have a mobility test result that suggests a higher fall risk.
Springfield, OregonAges 65–90 - NCT05788666Recruiting
GeriKit check-up for older adults after heart artery problems
This trial tests a “GeriKit” set of questions and measurements to better understand health and needs in people age 75+ after a heart attack or related procedures. It may help doctors plan more personalized care during recovery.
New York, New YorkAges 75–100 - NCT05786417RecruitingPhase 4
Medication comparison for older adults with stable heart pain
This trial tests which heart medications work best for older adults who have stable angina (predictable chest pain) and multiple other long-term health problems. You may be asked to start or adjust medications and attend regular follow-up visits to see which approach controls symptoms and outcomes.
New Haven, ConnecticutAges 65 years+ - NCT05790720Recruiting
Propofol dosing study for older adults
This study looks at how the anesthetic drug propofol works in older adults during planned surgeries. The goal is to find the right dose for safe and effective anesthesia.
Santiago, Santiago MetropolitanAges 65–99 - NCT05754151Recruiting
Mobile therapy for anxiety and depression in adults 40+
This trial tests whether a phone or tablet version of cognitive behavioral therapy (CBT) can help people ages 40 and older with anxiety or depression. It may help you manage symptoms with skills you can use between sessions.
New York, New YorkAges 40 years+ - NCT05752500Recruiting
Behavior coaching to help older adults with HIV move more
This study tests a tailored behavioral coaching program to increase physical activity in adults age 50+ who have HIV and are currently not very active. It may help you build safer, more routine movement using a Fitbit for tracking.
Minneapolis, MinnesotaAges 50 years+ - NCT05761860RecruitingEarly Phase 1
Oxytocin to lower opioid misuse risk and pain in older adults
This early-phase study tests whether oxytocin (a hormone-like medication) can reduce how “appealing” opioids feel and also reduce pain. It’s aimed at older adults who have used opioids before but are not currently dealing with chronic pain most days.
Gainesville, FloridaAges 45–85 - NCT05725668Recruiting
Dual-task exercise to help prevent falls in memory trouble
This study tests a type of exercise training (doing a physical task while also doing a thinking task) to help older adults with mild memory problems prevent falls. If you have fallen before or have trouble with balance, this program may help you improve safety and coordination.
Springfield, OregonAges 65–95 - NCT05700058Recruiting
Testing how different Super-whey doses affect muscle growth
This study checks how different doses of “Super-whey” influence muscle protein building in adults. It may help figure out the best whey dose for building muscle, especially in older adults.
DerbyAges 65–85 - NCT05676944Recruiting
Cochlear-like implant to help balance in older adults
This study tests a surgically placed implant aimed at improving balance and eye-stabilizing reflexes in older adults who have long-lasting, hard-to-treat inner-ear balance problems. You may be able to help researchers learn whether the device plus training can reduce dizziness and improve movement stability.
Baltimore, MarylandAges 65–90 - NCT05556928Recruiting
Cancer and aging study for adults with blood cancers
This study builds a registry to learn how aging and “resilience” relate to outcomes in people with blood cancers. You may be asked to complete questionnaires during UAB visits, which can help researchers better understand needs in older adults.
Birmingham, AlabamaAges 50 years+ - NCT05642884Recruiting
Pre-surgery program for older adults getting stem cell transplant
This study checks whether a “pre-surgery” health coaching program is practical and safe for older people with multiple myeloma who are scheduled for an autologous stem cell transplant. It may help patients prepare better for transplant recovery, and the study will see if the plan can be carried out smoothly.
Birmingham, AlabamaAges 60 years+ - NCT05612347Recruiting
Compare stool test vs colonoscopy for older adults with polyps
This study compares two ways to check for colon polyps in older adults: using a stool test versus having a colonoscopy. It may help find a simpler option if you only had a small number of lower-risk polyps before.
Birmingham, AlabamaAges 65–82
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Common questions
- Are there clinical trials for older adults?
- Yes. Clin2 currently lists 526 recruiting older adults studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a older adults trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a older adults trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.