Clinical trials
Older Adults clinical trials
Below are recruiting older adults clinical trials, each written for real people, not researchers. We’re tracking 519 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06375681Recruiting
Brain training study for younger and older adults
This study compares different types of memory and thinking exercises in younger and older healthy adults. It tests whether a specific computer-based training program can improve mental abilities like attention and problem-solving.
Riverside, CaliforniaAges 18–85 - NCT06317649RecruitingPhase 2
Venetoclax and HMA for older adults with FLT3-mutated AML
This trial tests a combination of two drugs (venetoclax and a hypomethylating agent) plus a targeted FLT3 inhibitor for older or frail patients with a specific genetic change in their acute myeloid leukemia. The goal is to see if this treatment is safe and effective without using the strongest chemotherapy.
Birmingham, AlabamaAges 18 years+ - NCT06362824Recruiting
Physical activity study for older Hispanic adults
This study tests ways to help older Hispanic/Latino(a) adults become more physically active. You will be randomly assigned to one of two programs, and the study lasts up to 20 weeks. It includes wearing a small activity tracker and filling out questionnaires.
San Diego, CaliforniaAges 55–89 - NCT06944964Recruiting
Single vs double implant for broken thigh bone near knee
This trial compares using one implant versus two implants to fix a broken thigh bone near the knee in older adults or those with certain health conditions. It aims to see which approach helps people heal better and recover more quickly.
New Westminster, British ColumbiaAges 18–100 - NCT06636058Recruiting
Digital treatment for weight and mood in adults 50+
This study tests a digital program that helps with weight loss and depression at the same time. It is designed for Black, Hispanic, and other adults over 50 who carry extra weight and feel down.
Chicago, IllinoisAges 50–74 - NCT07046078RecruitingPhase 2
Chemo, radiation, and donor transplant for older adults with high-risk AML
This trial tests a combination of chemotherapy (FLAG-Ida) followed by low-dose total body radiation and a stem cell transplant from a donor. It is for people age 60 and older with newly diagnosed high-risk blood cancers, aiming to improve outcomes with a less intense transplant preparative regimen.
Seattle, WashingtonAges 18 years+ - NCT07394790Recruiting
Exercise program for adults 65 and older
This study tests if a personalized exercise program prescribed by your doctor can help people 65 and older stay active and healthy. You would meet with a healthcare team to get a simple exercise plan and see how it affects your well-being.
Villoría, SalamancaAges 65 years+ - NCT06617806Recruiting
Preventing falls in very old, active adults
This trial tests if advanced practice nurses can help prevent falls in robust adults aged 80 and older. It may help you stay independent and avoid injuries.
Nantes, Loire-AtlantiqueAges 80 years+ - NCT06874842RecruitingPhase 1
Testing a new shingles vaccine in adults 40 and older
This trial tests a new shingles vaccine (LYB004) in adults 40 and older. It looks at how safe the vaccine is and how well it helps your body build protection against shingles.
MeizhouAges 40 years+ - NCT01132859Recruiting
Study of how immune cells respond in adults
This study looks at how your body’s immune system reacts in different tissues by collecting and storing samples for research. You might be able to join if you’re an adult and can consent, and if you don’t have certain bleeding risks that could make sample collection unsafe.
Bethesda, MarylandAges 18–120 - NCT07734649RecruitingPhase 1/Phase 2
RSV and HMPV vaccine study for adults 60 and older
This study tests a new vaccine that targets two respiratory viruses, RSV and HMPV, to see if it's safe and effective in adults 60 years and older. It may help prevent serious lung infections caused by these viruses.
Gadsden, AlabamaAges 60 years+ - NCT06045247RecruitingPhase 2
Epcoritamab with low-intensity chemo for older or frail patients with new lymphoma
This study tests a new immunotherapy drug (epcoritamab) combined with a milder chemotherapy (rituximab-mini CVP) for older or frail patients who cannot receive standard strong chemo. It aims to effectively treat newly diagnosed diffuse large B-cell lymphoma with fewer side effects.
Houston, TexasAges 18 years+ - NCT06303193RecruitingPhase 1/Phase 2
Testing a kinase inhibitor drug for MDS and MDS/MPN in adults and teens
This trial tests a drug called pacritinib in people with myelodysplastic syndromes (MDS) or MDS/myeloproliferative neoplasms (MDS/MPN). The drug targets several proteins that may help control the disease, especially for those who have not responded to other treatments.
Bethesda, MarylandAges 12–120 - NCT07176455Enrolling by invitation
Dietary habits after stomach cancer surgery
This trial studies how older stomach cancer survivors' eating habits change after surgery and tests ways to help them eat healthier. It focuses on people who just had their stomach cancer removed.
NanjingAges 60 years+ - NCT01137825Recruiting
Older patient cancer registry for a health check
This study is a registry that collects information from older adults who may be dealing with cancer. It includes a short health and function check to help doctors understand needs and guide care, even for people who turn out not to have cancer.
Boone, North CarolinaAges 65 years+
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Common questions
- Are there clinical trials for older adults?
- Yes. Clin2 currently lists 519 recruiting older adults studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a older adults trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a older adults trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.