Clinical trials
Oncology clinical trials
Below are recruiting oncology clinical trials, each written for real people, not researchers. We’re tracking 782 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04322318RecruitingPhase 2
Study of combination chemotherapy for Wilms tumor in children
This Phase 2 trial tests combination chemotherapy for children with certain types of Wilms tumor—either newly diagnosed diffuse anaplastic Wilms tumor or favorable Wilms tumor that has come back. The goal is to see how well the treatment controls the tumor and is tolerable for children.
Birmingham, AlabamaAges Up to 30 years - NCT04293562RecruitingPhase 3
Comparing chemotherapy options for newly diagnosed AML in young patients
This trial compares standard chemotherapy with newer drug combinations (CPX-351 and gilteritinib) for children and young adults with acute myeloid leukemia (AML), a type of blood cancer. It aims to find which treatment works better and who might benefit from targeted therapy based on specific genetic changes (FLT3 mutations).
Birmingham, AlabamaAges 6 months–21 years - NCT04266093Enrolling by invitation
Gene therapy follow-up for adults previously treated at NCI
This study is a follow-up check for people who were previously enrolled in certain NCI gene therapy treatment studies. It helps the research team monitor long-term effects and outcomes after treatment.
Bethesda, MarylandAges 18–120 - NCT04256317RecruitingPhase 2/Phase 3
Azacitidine pills with or without venetoclax for certain blood cancers
This study tests whether a pill form of azacitidine (ASTX030) helps people with myelodysplastic syndromes (MDS), CMML, or AML. Some groups may also receive venetoclax; the goal is better blood cancer control for people who aren’t good candidates for intensive chemotherapy.
Los Angeles, CaliforniaAges 18 years+ - NCT02693535RecruitingPhase 2
Targeted drug testing for advanced cancer with tumor gene changes
This trial tests whether FDA-approved targeted drugs can help people with advanced cancer whose tumors have specific gene changes. It aims to match your tumor's unique genetic profile to a drug that may work better for you.
Birmingham, AlabamaAges 12 years+ - NCT04330456Recruiting
Radiation plus surgery for first soft tissue sarcoma
This trial studies a treatment plan for newly diagnosed soft tissue sarcoma that combines precisely targeted radiation before surgery and conformal radiation after surgery. It may help by improving tumor control while allowing the surgeon to remove the tumor safely.
Saint PetersburgAges 18–75 - NCT04333537RecruitingPhase 2/Phase 3
Sentinel node biopsy versus standard neck surgery for early mouth cancer
This trial compares two ways of checking whether early oral cavity squamous cell cancer has spread to neck lymph nodes. It tests whether sentinel lymph node biopsy can find spread as well as standard neck dissection, while potentially reducing more extensive surgery for some people.
Birmingham, AlabamaAges 18 years+ - NCT04264975Recruiting
Using gut microbiome tests and stool transfer in immunotherapy cancer
This trial studies whether changes in gut bacteria can help predict how well immunotherapy works for solid cancers. It also tests whether stool (fecal microbiota) from certain immunotherapy-responding people can improve outcomes for others who are not responding well.
Seoul, SeoulAges 19 years+ - NCT04297605RecruitingPhase 1
Pembrolizumab plus chemotherapy for advanced lung cancer
This Phase 1 study tests pembrolizumab (an immunotherapy) given together with a chemotherapy drug to treat non-small cell lung cancer that is locally advanced or has spread. It’s aimed at people who can handle treatment with an ECOG performance status of 2, including some with certain types of brain metastases.
Rochester, New YorkAges 18 years+ - NCT04349527Recruiting
Comparing breast-conserving surgeries and how you feel after
This trial compares two breast-conserving surgery techniques to see how they affect cosmetic results (how the breast looks), quality of life, and patient satisfaction. It may help guide the best surgical approach for people eligible for breast conservation.
BudapestAges 18–65 - NCT04268849RecruitingPhase 3
IV vs oral iron after weight-loss surgery
This Phase 3 study compares taking iron through an IV versus by mouth to treat iron-deficiency anemia after Roux-en-Y gastric bypass or sleeve gastrectomy. The goal is to see which method works better and is safer for improving iron levels and blood counts.
Baltimore, MarylandAges 18 years+ - NCT04356235Recruiting
Comparing immediate vs delayed breast implant reconstruction results
This study compares two timing options for rebuilding the breast with implants, looking at cosmetic results, quality of life, and patient satisfaction. It may help you understand which approach could fit you better and what to expect over follow-up time.
BudapestAges 18–65 - NCT04293796Recruiting
Skipping breast surgery after complete response
This trial looks at whether some people with breast cancer can safely avoid breast surgery after they respond completely to treatment before surgery. If you have no remaining cancer in the tissue and lymph node tests, this study checks whether the “watch-and-wait” approach is feasible and safe.
Saint PetersburgAges 18–70 - NCT04345081Recruiting
Compare two breast surgery skin-sparing methods and recovery
This trial compares two types of mastectomy (with skin and nipple options) and implant reconstruction to see which gives better cosmetic results, comfort, and satisfaction. You may help doctors learn which approach leads to a better quality of life after surgery.
BudapestAges 18–65 - NCT04268121RecruitingPhase 2
Neoadjuvant chemotherapy before surgery for certain digestive neuroendocrine cancers
This study looks at whether chemotherapy given before surgery improves how long patients live without the cancer coming back. It’s aimed at people with localized, poorly differentiated digestive neuroendocrine carcinoma with a higher growth rate marker.
AmiensAges 18 years+ - NCT06876714RecruitingPhase 3
Shorter vs Longer HER2 Therapy for Breast Cancer with Complete Response
This trial compares 6 months versus 12 months of HER2-targeted therapy for people with HER2+ breast cancer who had a complete response after chemo and trastuzumab. The goal is to see if a shorter treatment is just as effective.
Phoenix, ArizonaAges 18 years+ - NCT07739121Recruiting
Testing AI vs. tumor boards for cancer treatment advice
This trial compares treatment recommendations from large language models (AI) against those from experienced tumor boards for five common cancer types. The goal is to see if AI can help doctors make better decisions.
Boulogne-BillancourtAges 18 years+ - NCT04217512RecruitingPhase 3
Pantoprazole to protect kidneys during head and neck cancer treatment
This trial tests whether pantoprazole can help prevent kidney damage caused by a chemotherapy drug called cisplatin. It may help protect kidney function in people with head and neck cancer receiving cisplatin.
TantaAges Any age - NCT04251052Recruiting
Compare two surgeries to lower ovarian cancer risk in BRCA1 carriers
This study compares two risk-reducing surgery plans for people with a BRCA1 genetic change to see which approach helps lower ovarian cancer risk. You may be asked to have the study procedure sooner or later depending on your chosen plan.
Birmingham, AlabamaAges 35–50 - NCT04242095Recruiting
Immunotherapy side effects research study
This study collects blood, stool, and tissue samples from people who have had side effects from immunotherapy (a type of cancer treatment that helps your immune system fight cancer). It aims to learn more about these side effects, so doctors can better manage them in the future.
Anchorage, AlaskaAges Any age - NCT04150042RecruitingPhase 1
Test of chemotherapy plus your own stem cells for metastatic cancer
This Phase 1 trial tests a treatment approach using standard chemotherapy along with stem cells taken from you to treat metastatic pancreatic or breast cancer. It is mainly designed to check safety and find the best way to give the treatment, and it may offer an option for people whose cancer has spread.
Boston, MassachusettsAges 18 years+ - NCT04167696RecruitingPhase 1
Dose-finding drug study for AML or MDS after standard options fail
This Phase 1 trial tests CYAD-02 to find the safest and recommended dose for people with AML or MDS that has returned or did not respond to prior treatment. It may help if you have limited treatment options, but participation also requires meeting specific heart, lung, and lab safety requirements.
Jacksonville, FloridaAges 18 years+ - NCT04157127RecruitingPhase 1
Pancreatic cancer vaccine with chemotherapy before/around surgery
This early-stage trial tests a personalized immune “vaccine” made from dendritic cells, given alongside standard chemotherapy for pancreatic cancer that may be removable by surgery (resectable or borderline resectable). If it works, it may help your immune system better recognize and attack the cancer around the time of treatment.
Houston, TexasAges 18 years+ - NCT04243785RecruitingPhase 1
Testing BTX-A51 for hard-to-treat AML or high-risk MDS
This Phase 1 study tests BTX-A51 in adults with relapsed or refractory acute myeloid leukemia (AML) or high-risk myelodysplastic syndrome (MDS). It’s designed to see if the treatment can be given safely and to learn how it works in people whose standard treatments have not helped or are no longer an option.
Duarte, CaliforniaAges 18 years+
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Common questions
- Are there clinical trials for oncology?
- Yes. Clin2 currently lists 782 recruiting oncology studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a oncology trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a oncology trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.