Clinical trials
Oral Surgery clinical trials
Below are recruiting oral surgery clinical trials, each written for real people, not researchers. We’re tracking 103 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06381791RecruitingPhase 1/Phase 2
CBD for pain after shoulder surgery
This study tests if CBD (a cannabis extract) can help manage pain after rotator cuff repair surgery. It aims to find a better way to control pain and reduce the need for stronger painkillers.
Houston, TexasAges 18 years+ - NCT05429099Recruiting
Planning study for jaw reconstruction surgery
This study helps teams plan surgery for people who need part of the lower jaw removed and rebuilt using special tissue flaps. It mainly looks at whether having specific pre-surgery CT images is possible and useful for reconstruction planning.
Vancouver, British ColumbiaAges 18 years+ - NCT06130332RecruitingPhase 2
Immunotherapy Plus Chemo Before Surgery for Early Oral Cancer
This trial tests a new immunotherapy drug (tirellizumab) combined with chemotherapy before surgery for early-stage oral cancer. It aims to see if this combination can help shrink the tumor and improve outcomes.
Guangzhou, GuangdongAges 18–75 - NCT07158476RecruitingPhase 4
Steroid injection for pain after ACL repair
This trial tests whether a single dose of methylprednisolone (a steroid) can reduce pain after ACL knee surgery. You will be randomly assigned to receive either the steroid or a placebo, and your pain levels will be tracked.
St Louis, MissouriAges 13–50 - NCT06957366Recruiting
Managing Blood Thinners Before High-Risk Surgery
This study looks at how to safely manage your blood thinner (DOAC) around the time of a planned, high-bleed-risk surgery or procedure involving a spinal needle. The goal is to find the best way to stop and restart your medication to prevent bleeding and clotting problems.
Hartford, ConnecticutAges 18 years+ - NCT07220850Recruiting
Oral health help for caregivers of kids having dental surgery
This trial tests a program to help caregivers improve their child's oral health after dental surgery. It may be a good fit if you care for a child under 8 years old who is getting dental surgery at the University of Illinois at Chicago clinic.
Chicago, IllinoisAges Up to 7 years - NCT07568249Recruiting
How full arch dental implants affect your quality of life
This study looks at how getting a full set of dental implants (for a whole upper or lower jaw) affects your oral health and quality of life. Researchers want to see how your experience changes from before treatment through recovery.
Lisbon, Lisbon DistrictAges 18 years+ - NCT07430670Recruiting
Gum healing with oral and tissue care after recession surgery
This study tests a special oral product and skin care along with gum surgery for people with gum recession on a lower front tooth. It looks at whether the product helps the healing process after adding a small piece of gum tissue.
Madrid, MadridAges 18 years+ - NCT04552080RecruitingPhase 4
Antibiotics around sinus and bone graft implants to prevent problems
This trial studies whether taking antibiotics through the body (systemic antibiotics) after sinus-lift and bone-graft dental implant surgery can reduce post-surgery complications and improve patient comfort. It compares outcomes that matter to patients after implant placement using guided bone regeneration and a sinus floor elevation.
GrazAges 21 years+ - NCT07712120Recruiting
Biofeedback to help with head and neck cancer surgery
This study tests a brief psychological support program that uses biofeedback (a tool that helps you learn to control body signals like heart rate) to help patients scheduled for head and neck cancer surgery. It aims to see if the program can improve well-being and recovery.
TurinAges 18 years+ - NCT07062757Enrolling by invitation
Massage and melatonin for jaw surgery recovery
This study tests whether combining gentle lymphatic drainage massage with melatonin can reduce pain and swelling after jaw surgery. If you are scheduled for jaw surgery for the first time and are otherwise healthy, you may be able to join.
Istanbul, FatihAges 16–55 - NCT03849443RecruitingEarly Phase 1
Testing tranexamic acid to reduce bleeding after spine fusion
This trial studies whether a single dose or multiple doses of tranexamic acid (TXA) can reduce the chance you need a blood transfusion after spine fusion surgery. It also compares two different ways TXA may be given (by mouth and through a vein) to see which approach works best and is safe.
Chicago, IllinoisAges 18 years+ - NCT07754812RecruitingPhase 4
Oral paclitaxel with immunotherapy and SBRT before surgery for older adults with lung cancer
This trial tests a new way to treat non-small cell lung cancer in people aged 70 or older. You will receive oral chemotherapy (paclitaxel) with immunotherapy and focused radiation (SBRT) before surgery, hoping to shrink the tumor and improve outcomes.
Guangzhou, GuangdongAges 70 years+ - NCT06925061RecruitingPhase 2
Testing EXL01 to prevent Crohn's disease return after surgery
This study tests a new oral treatment called EXL01 to see if it can prevent Crohn's disease from coming back after surgery to remove part of the small and large intestine. It may be an option if you are not planning to use strong immune-suppressing drugs (except anti-TNF) in the next 6 months.
Clermont-FerrandAges 18 years+ - NCT07371611RecruitingPhase 3
Sintilimab plus chemo before and after surgery for advanced oral cancer
This trial tests whether adding an immunotherapy drug (sintilimab) to standard chemotherapy before and after surgery can improve outcomes for people with advanced oral squamous cell carcinoma. The treatment is given first to shrink the tumor, then again after surgery to help prevent recurrence.
Guangzhou, GuangdongAges 18–75 - NCT07309848Recruiting
Hip fracture surgery timing and blood transfusion risk on DOACs
This study looks at whether the timing of hip fracture surgery affects the need for blood transfusions in patients taking blood thinners (DOACs). It might help guide better care for people on these medications.
AlmeloAges Any age - NCT06180356RecruitingPhase 2
Niraparib after surgery for ovarian cancer with limited spread
This trial is testing a second course of niraparib (a PARP inhibitor) after surgery for ovarian cancer that has come back in just a few spots. It aims to see if restarting niraparib can help keep the cancer from coming back again.
A CoruñaAges 18 years+ - NCT02290145RecruitingPhase 2
Study of Cyclin D1–targeted chemotherapy before oral cancer surgery
This Phase 2 trial tests a chemotherapy plan given first (before surgery) for people with oral squamous cell carcinoma that has specific cancer markers and lymph node involvement. It aims to shrink or control the cancer so treatment after may work better.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT03297281Recruiting
Stopping or continuing blood thinners during prostate vaporization
This study compares whether people can safely stop or continue oral blood thinners during a prostate procedure called photovaporization. It may help reduce bleeding risk without increasing dangerous clot risks for the right patients.
ToulouseAges 18 years+ - NCT07751302Recruiting
Follow-up vs. chemo after surgery for early stomach cancer
This trial compares two approaches after surgery for early-stage stomach or GEJ cancer: close monitoring (follow-up) vs. adjuvant chemotherapy (chemo given after surgery). It aims to see if follow-up alone is as good as chemo for patients with this stage, potentially avoiding chemo side effects.
Xi'an, ShaanxiAges 18 years+ - NCT06948071Recruiting
Enhanced recovery after surgery for complicated appendicitis
This study tests a special recovery program for people having laparoscopic surgery for a severe type of appendicitis. It aims to help you heal faster and leave the hospital sooner.
Los Angeles, CaliforniaAges 18 years+ - NCT07498374Recruiting
Drug-eluting stent for eosinophilic sinusitis with nasal polyps
This trial tests a fully dissolvable stent that releases medication inside the sinuses after surgery. It is for patients with a specific type of sinusitis (eosinophilic) and nasal polyps who either need surgery or have had surgery and show early signs of inflammation returning.
Xi'an, ShaanxiAges 18–65 - NCT06470217RecruitingPhase 2
Study of tirilizumab plus chemo for advanced oral cancer
This trial tests a combination of immunotherapy (tirilizumab) and two chemotherapy drugs (albumin-bound paclitaxel and cisplatin) for people with advanced but removable oral cancer. The goal is to see if this treatment shrinks the tumor before surgery and improves outcomes.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT05520593Recruiting
Drinking plan before surgery to support same-day joint replacement
This trial tests whether a specific pre-surgery oral drinking (hydration) plan can help people feel and recover better after outpatient (same-day) hip or knee replacement surgery. It may help support safe same-day discharge for the right patients.
New York, New YorkAges 18–75
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Common questions
- Are there clinical trials for oral surgery?
- Yes. Clin2 currently lists 103 recruiting oral surgery studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a oral surgery trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a oral surgery trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.