Clinical trials
Oropharynx Cancer clinical trials
Below are recruiting oropharynx cancer clinical trials, each written for real people, not researchers. We’re tracking 39 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06254911RecruitingPhase 2
Immunotherapy before surgery for HPV-related throat cancer
This trial tests whether giving the drug atezolizumab before surgery can help shrink HPV-related throat cancer and improve outcomes. Atezolizumab helps your immune system fight cancer cells.
Atlanta, GeorgiaAges 18 years+ - NCT05582122RecruitingPhase 2
Tracking HPV16 DNA in blood to spot cancer coming back
This study checks whether a blood test for HPV16 DNA can predict when HPV-related throat cancer comes back after treatment. It may help improve follow-up care by catching recurrence earlier.
Saint-Denis, La RéunionAges 18 years+ - NCT06563362RecruitingPhase 2
Personalized radiation for oropharyngeal cancer
This trial tests a personalized approach to radiation therapy for oropharyngeal cancer. The goal is to safely reduce the amount of radiation to healthy lymph nodes, which may lower side effects while still effectively treating the cancer.
Zurich, Canton of ZurichAges 18 years+ - NCT06821243Recruiting
Finding markers in HPV-related throat cancer to guide treatment
This study looks for certain markers in people with HPV-related throat cancer that could help doctors choose the best treatment. If you are planning to have surgery for your throat cancer, you may be able to join.
Rome, RomeAges 18 years+ - NCT06600295Recruiting
Taste changes and nutrition in new cancer patients
This study looks at how cancer and its treatments affect taste and nutrition. It aims to find ways to help patients maintain good nutrition during treatment.
DijonAges 18 years+ - NCT05451303Recruiting
Testing for oral and throat cancer risk with a mouth test
This trial studies how well an at-home or clinic mouth test (OralViome Cancer Testing System) can detect signs of risk for oral or throat cancer. You may benefit by getting cancer-risk testing if you are considered high risk, though results will guide whether further evaluation is needed.
New York, New YorkAges 18 years+ - NCT05649865Recruiting
Monitor HPV DNA in throat cancer to guide early response
This study checks a substance called HPV DNA in your blood to see how your HPV-positive throat cancer responds early during treatment. It may help doctors spot who is responding well and who may need closer attention sooner.
Lund, Skåne CountyAges 18 years+ - NCT06223568RecruitingPhase 2
Chemo with or without a vaccine for HPV-related throat cancer
This trial tests whether adding an immunotherapy vaccine (PRGN-2009) to standard chemotherapy before surgery works better than chemotherapy alone for people with newly diagnosed HPV-positive oropharyngeal (head and neck) cancer.
Bethesda, MarylandAges 18–120 - NCT05894083RecruitingPhase 2
PET-Scan Tailored De-escalation for p16+ throat cancer
This trial tests a treatment plan that may lower (de-escalate) therapy intensity for certain p16+ or HPV-positive throat cancers. It uses PET scan results and tumor features to try to keep cancer control while reducing side effects.
Ann Arbor, MichiganAges 18 years+ - NCT04104945Recruiting
Trial to reduce radiation fields in p16+ oropharyngeal cancer
This study tests whether shrinking the “planned radiation area” (elective treatment volumes) can still treat p16-positive oropharyngeal cancer effectively. It may help reduce unnecessary radiation to nearby healthy tissues while keeping the cancer treatment curative.
Calgary, AlbertaAges 18 years+ - NCT04564989Recruiting
Biomarker study for HPV-related throat cancer outcomes
This observational study checks how well a blood test for HPV DNA (and other tumor genetic markers) predicts outcomes in certain throat cancers. It may help doctors better track the disease and plan treatment, because the trial validates these lab signals against real-world results.
Rochester, MinnesotaAges 18 years+ - NCT07548268Recruiting
Ultrasound imaging for suspected throat cancer
This study tests a new ultrasound method to help doctors identify throat cancer earlier. You would undergo imaging scans to see if ultrasound can better detect cancer in the back of the throat.
AarhusAges 18 years+ - NCT07203911Recruiting
Ultrasound guidance for oral cancer surgery
This trial tests whether surgeons can use ultrasound during surgery to better guide the removal of oral cancer. It may help ensure all cancer is removed while sparing healthy tissue.
Stanford, CaliforniaAges 18 years+ - NCT07712120Recruiting
Biofeedback to help with head and neck cancer surgery
This study tests a brief psychological support program that uses biofeedback (a tool that helps you learn to control body signals like heart rate) to help patients scheduled for head and neck cancer surgery. It aims to see if the program can improve well-being and recovery.
TurinAges 18 years+ - NCT05918510Recruiting
Blood and tumor study for virus markers in throat cancer
This study looks at virus-related markers and tiny gene regulators (microRNAs) in tumor tissue from people with certain throat cancers caused by human papilloma virus (HPV). It’s observational, meaning it does not change your treatment, but results may help doctors better understand these cancers and how they behave.
RomeAges 18 years+
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Common questions
- Are there clinical trials for oropharynx cancer?
- Yes. Clin2 currently lists 39 recruiting oropharynx cancer studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a oropharynx cancer trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a oropharynx cancer trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.