Clinical trials
Orthodontics clinical trials
Below are recruiting orthodontics clinical trials, each written for real people, not researchers. We’re tracking 84 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07288853Recruiting
Can a smartphone app help teens with braces keep cleaner teeth?
This trial tests whether a smartphone app with reminders can help teenagers with braces keep their teeth and gums cleaner. If you're getting braces and have a smartphone, you might be eligible.
Kuantan, PahangAges 12–18 - NCT05733676Recruiting
MI Paste Plus vs resin for white spots after braces
This trial compares two tooth treatments to see which one works better for “white spot” areas that can appear after braces come off. If you have mild plaque buildup and at least one white spot on front teeth, you may be eligible to test one of these options and improve tooth surface healing.
Edmonton, AlbertaAges 12–21 - NCT07445555Recruiting
Gum Recession Study: Braces vs. No Braces
This study looks at gum recession (when gums pull away from teeth) in adults, comparing those who had braces in the past to those who did not. It aims to understand if orthodontic treatment affects gum health.
LeuvenAges 18 years+ - NCT07521267Recruiting
Nano-coated screws for teeth straightening in teens
This trial tests special small screws coated with nano-material to help move upper front teeth back into place during braces treatment. The screws act as anchors to make tooth movement more effective for patients with protruding upper front teeth.
Cairo, Cairo GovernorateAges 14–20 - NCT07533240Recruiting
Tooth Wear Treatment Effects on Bite and Jaw
This study looks at how a specific tooth-restoration treatment (called the One-Step No-Prep protocol) affects your bite alignment and jaw joint over time. Researchers want to understand if this treatment helps improve how your teeth fit together.
LiègeAges 18 years+ - NCT07619014Recruiting
Miswak vs. toothbrush for cleaning teeth with braces
This study compares how well a miswak (a natural chewing stick) and a regular toothbrush remove plaque buildup around orthodontic braces. If you wear braces, this trial tests whether miswak might be an equally effective cleaning option.
HomsAges 18–30 - NCT07752498Enrolling by invitation
Long-term results from twin block treatment
This study checks whether the results from an earlier treatment with the Twin Block appliance, which corrects bite problems, hold up over time. It looks at how stable the teeth and jaw remain years after treatment.
Jönköping, Jönköping CountyAges Any age - NCT05492773Recruiting
Clear aligner treatment with tiny bone punctures to speed tooth movement
This trial tests whether a technique called tiny “micro-punctures” in the jaw bone can speed up orthodontic tooth movement in people with moderate front-lower tooth crowding. It uses clear aligners and may help teeth move faster, but only if you meet the dental and medical safety requirements.
HamaAges 18–26 - NCT06834139Enrolling by invitation
Testing a new cleaning device for people with braces
This trial tests a device called the Neo Pill to see if it helps keep teeth clean for people with braces. It compares the device to regular brushing and may help reduce plaque and gum problems during orthodontic treatment.
Kragujevac, SerbiaAges 18 years+ - NCT06529601Recruiting
Digital vs. traditional lower tooth retainers after braces
This trial compares two types of retainers (wire bonded to the back of your lower front teeth) after braces. One retainer is made with a digital design (CAD/CAM), the other is made the traditional way.
FlorenceAges 13–20 - NCT05851963Recruiting
Toothbrushing help for teens with fixed braces
This study looks at whether using specific toothbrushes in daily life can improve dental gum and tooth health for teens with fixed braces. It may help by testing simple at-home brushing routines that could reduce gum problems during orthodontic treatment.
NancyAges 11–15 - NCT07534423Recruiting
Finishing teeth after braces removal training
This study teaches dental professionals best practices for completing and polishing teeth immediately after braces are removed. It's designed for orthodontists and dentists who work with braces to improve their finishing techniques.
Roma, RMAges Any age - NCT07191158Recruiting
Testing a 3D-printed molar-moving device for bite correction
This trial is testing a new 3D-printed device that moves your upper molars backward to correct a specific type of bite problem (Class II). It may help you if you have a clear overbite on both sides and your second molars are already in place.
Baghdad, Al-RussafaAges 16–30 - NCT06975358Recruiting
Faster braces with gum surgery and growth factor injections
This study tests if a small gum surgery (alveolar decortication) plus a natural growth factor injection (CGF) can speed up tooth movement in people who need braces and have two teeth removed. It may help you have a shorter treatment time.
Tanta, TantaAges 16–22 - NCT07155343RecruitingEarly Phase 1
Comparing two types of glue for braces in teens and adults
This early-phase trial tests if a newer, faster-setting glue (bulk-fill composite) works as well as the standard glue for attaching braces. It's for people aged 13 to 40 who are starting or continuing fixed braces treatment.
Karachi, SindhAges 13–40 - NCT07098325Recruiting
3d printed retainers for braces after treatment
This trial tests how your mouth reacts to a 3d printed retainer after braces. It may help you keep your teeth straight.
AsyutAges Any age - NCT06734325Recruiting
Mobile health program for braces patients
This study uses text messages on WhatsApp to help young people with braces improve their brushing habits. It will test whether a simple mobile program can keep your teeth cleaner and help you learn more about oral health.
AlexandriaAges 16–25 - NCT07660146Recruiting
Predicting extraction needs for orthodontic treatment
This trial tests a method to help dentists decide if you need tooth extractions before braces. Researchers will look at dental models to see if this analysis tool is accurate.
Cairo, Giza GovernorateAges 12 years+ - NCT07030023Enrolling by invitation
Diagnosing Wire Syndrome in people with fixed retainers
This trial looks at people who have a fixed orthodontic wire retainer to see if they have a condition called Wire Syndrome. You may be eligible if you have this retainer, are healthy, and have your dental records available.
Nice, Alpes MaritimesAges 18 years+ - NCT07693972Recruiting
Probiotic vs zinc mouthwash for bad breath and plaque in braces
This trial compares a probiotic mouthwash to a zinc and chlorhexidine mouthwash to see which is better at controlling bad breath and plaque for people with braces. It aims to find a gentler option that still works well.
Baghdad, AlkarghAges 18–30 - NCT07146464Recruiting
Peptide vs calcium paste for early cavity spots
This trial tests whether a new peptide treatment or a calcium-phosphate paste works better at reversing early white-spot cavities on front teeth. If you're a young adult with early decay on your front teeth, you may be able to join.
Cairo, Cairo GovernorateAges 15–25 - NCT05650359Recruiting
Light therapy study for braces alignment in adults
This trial studies whether Orthopulse light therapy (a form of light treatment) can help during orthodontic treatment with fixed braces. It’s for adults who need braces for crowded front lower teeth, and it will compare outcomes during the alignment phase.
Chandler, ArizonaAges 18 years+ - NCT07293975Recruiting
Pain relief during brace removal with TENS or vibration
This study tests two drug-free methods—gentle electrical stimulation (TENS) and high-frequency vibration—to see if they can reduce pain when braces are removed.
BaghdadAges 15–35 - NCT07180849Recruiting
New fluoride varnish vs standard varnish for braces plaque
This trial compares a new fluoride varnish that contains tiny titanium particles (nanoparticles) to a standard fluoride varnish. It tests which one is better at preventing plaque buildup for people getting braces.
IslamabadAges 16–30
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Common questions
- Are there clinical trials for orthodontics?
- Yes. Clin2 currently lists 84 recruiting orthodontics studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a orthodontics trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a orthodontics trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.