Clinical trials
Orthodontics clinical trials
Below are recruiting orthodontics clinical trials, each written for real people, not researchers. We’re tracking 81 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07107100Recruiting
Comparing two types of retainers after braces
This study compares two types of retainers (a wire that keeps teeth in place) after braces are removed: one that is directly bonded to the teeth and one that is made indirectly. It looks at which type keeps gums healthy, lasts longer, and how likely it is to break.
Karachi, SindhAges 13–40 - NCT07091422Recruiting
Testing a new brace glue: does it hold better?
This trial tests a new no-etching glue for braces. Half of your mouth will get the new glue, the other half a standard glue, to see which one holds the brackets better over a year.
Baltimore, MarylandAges 14–35 - NCT06944860Recruiting
3D-printed vs. traditional twin block braces for kids
This trial compares a new 3D-printed twin block brace to a traditional one for children with a large overbite (overjet ≥7 mm). It checks how well germs stick, how smooth the brace is, and how well it works—plus how children feel about it.
Kuala Lumpur, Kuala LumpurAges 10–14 - NCT06948162Recruiting
Dental MRI for routine dental care
This study tests whether a special MRI machine can take detailed images of teeth and jaws for routine dental care. It may help find problems without using X-rays.
Minneapolis, MinnesotaAges 18 years+ - NCT06824493Recruiting
How Braces Affect Mouth Bacteria and Saliva
This study looks at how braces (orthodontic treatment) change the bacteria and proteins in your mouth. Healthy volunteers who have never had dental work or cavities are needed to provide saliva samples before and during treatment.
Xi'an, ShaanxiAges 6–18 - NCT06187337Recruiting
Expanding the upper jaw to fix crowded front teeth in children
This trial tests if expanding the upper jaw can make room for crowded front teeth in children who still have some baby teeth. It aims to help the side front teeth come in properly without needing braces later.
CoppitoAges 6–16 - NCT06731465Enrolling by invitation
Clear aligners vs braces for crowded lower front teeth
This study compares clear aligners (removable trays) to traditional braces for treating crowded lower front teeth. It aims to see which method works better and is more comfortable for patients.
Sharjah city, Emirate of SharjahAges 16–45 - NCT05733676Recruiting
MI Paste Plus vs resin for white spots after braces
This trial compares two tooth treatments to see which one works better for “white spot” areas that can appear after braces come off. If you have mild plaque buildup and at least one white spot on front teeth, you may be eligible to test one of these options and improve tooth surface healing.
Edmonton, AlbertaAges 12–21 - NCT07879066Enrolling by invitation
Faster tooth movement after molar removal
This study tests a procedure to speed up tooth movement after removing certain back teeth. It may help you get braces treatment done faster.
Dhaka, BangladeshAges 16–25 - NCT05081258Recruiting
Tests presurgery shaping for newborn cleft lip and palate growth
This study looks at whether a presurgery orthodontic shaping method affects how newborns with a cleft lip and palate grow over time. It may help clinicians decide on the best early treatment approach.
Erlangen, BavariaAges 1 day–2 years - NCT06122805Recruiting
Electric vs. Manual Toothbrush for Kids with Cleft Lip/Palate
This study compares a special dual-light electric toothbrush to a regular manual toothbrush for kids and teens with cleft lip or palate who wear braces. The goal is to see which brush keeps teeth cleaner and gums healthier during orthodontic treatment and after oral surgery.
Los Angeles, CaliforniaAges 6–20 - NCT05710952Recruiting
Orthodontic braces study and how they affect jaw joints
This study looks at whether multi-attachment orthodontic treatment (either on the front or back of teeth) changes the temporomandibular joint, which is the jaw joint. The researchers will assess your jaw joint using a tool called Modjaw.
MontpellierAges 18 years+ - NCT07810699Recruiting
Laser or LED light for moving upper canine teeth
This study compares two types of light therapy, laser and LED, to see which one helps move your upper canine teeth faster and more comfortably during orthodontic treatment. It may help reduce treatment time and pain.
Can ThoAges 15–40 - NCT05650359Recruiting
Light therapy study for braces alignment in adults
This trial studies whether Orthopulse light therapy (a form of light treatment) can help during orthodontic treatment with fixed braces. It’s for adults who need braces for crowded front lower teeth, and it will compare outcomes during the alignment phase.
Chandler, ArizonaAges 18 years+ - NCT07773389Recruiting
Early vs late premolar removal for braces
This study compares removing two back teeth early versus later during braces treatment to see which timing leads to better tooth movement. It may help teens and young adults needing braces for crowded teeth or overbite.
IslamabadAges 13–25 - NCT07763808RecruitingPhase 2/Phase 3
Gum surgery for receding gums after braces
This study tests different surgical methods to repair receding gums that can happen after orthodontic treatment. If you have gum recession and are otherwise healthy, this trial may help improve your gum health and appearance.
BakuAges 18–70 - NCT07752498Enrolling by invitation
Long-term results from twin block treatment
This study checks whether the results from an earlier treatment with the Twin Block appliance, which corrects bite problems, hold up over time. It looks at how stable the teeth and jaw remain years after treatment.
Jönköping, Jönköping CountyAges Any age - NCT07693972Recruiting
Probiotic vs zinc mouthwash for bad breath and plaque in braces
This trial compares a probiotic mouthwash to a zinc and chlorhexidine mouthwash to see which is better at controlling bad breath and plaque for people with braces. It aims to find a gentler option that still works well.
Baghdad, AlkarghAges 18–30 - NCT07660146Recruiting
Predicting extraction needs for orthodontic treatment
This trial tests a method to help dentists decide if you need tooth extractions before braces. Researchers will look at dental models to see if this analysis tool is accurate.
Cairo, Giza GovernorateAges 12 years+ - NCT06685016Recruiting
Study of dental health after IPR with clear aligners
This study looks at how the teeth and gums are doing after a common orthodontic step called IPR (a slight smoothing between teeth) in people wearing clear aligners. It will help understand if this procedure keeps your mouth healthy.
NaplesAges 17–100 - NCT07645417Enrolling by invitation
Comparing Wires for Moving Upper Canine Teeth During Braces
This study tests two types of orthodontic wires to see which one more effectively moves your upper canine teeth backward when you're already wearing fixed braces. The goal is to find the best method for straightening your bite with minimal side effects.
DhakaAges 1.3 years–2.9 years - NCT07617480Enrolling by invitation
Orthodontic bracket bonding: acid etching with or without sandblasting
This study compares two methods of preparing tooth surfaces before attaching orthodontic brackets (the small squares glued to teeth during braces treatment). Researchers want to see which method—using acid alone or acid plus sandblasting—keeps brackets bonded better to your teeth.
DhakaAges 18–64 - NCT07566676Recruiting
Faster Upper Front Tooth Movement With Micro-holes
This study tests a new way to move upper front teeth into better position using braces combined with tiny holes made in the bone. The goal is to correct an overbite (when upper front teeth stick out too far) more quickly and effectively.
Cairo, Nasr CityAges 15–25 - NCT07567105Recruiting
Long-term stability of open-bite orthodontic treatment
This study looks at whether orthodontic treatment for anterior open bite (a gap between upper and lower front teeth when biting down) stays stable over time. The researchers want to understand what helps the correction last.
VantaaAges Any age
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Common questions
- Are there clinical trials for orthodontics?
- Yes. Clin2 currently lists 81 recruiting orthodontics studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a orthodontics trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a orthodontics trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.