Clinical trials
Osteoarthritis Knees Both clinical trials
Below are recruiting osteoarthritis knees both clinical trials, each written for real people, not researchers. We’re tracking 395 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07016672Recruiting
PRP vs. hyaluronic acid for advanced knee arthritis
This study compares two treatments—platelet-rich plasma (PRP) and hyaluronic acid (a lubricating injection)—for people with severe knee arthritis seen on MRI. The goal is to see which better reduces pain.
Toulon, VarAges 18 years+ - NCT07215572Recruiting
Group physical therapy for veterans with knee osteoarthritis
This trial studies whether a group physical therapy program can help veterans with knee osteoarthritis. It aims to see if this approach is practical and effective for improving knee pain and function.
Durham, North CarolinaAges Any age - NCT07301242Recruiting
Study of ciprofol in older adults having limb surgery
This trial studies how the drug ciprofol works in older adults undergoing elective orthopedic limb surgery. The goal is to understand how the body processes the drug and how it affects patients, which may help improve its use for anesthesia in the elderly.
ShanghaiAges 65 years+ - NCT07304323Recruiting
Predicting recovery after hip or knee replacement in 2018
This trial is for people who had hip or knee replacement surgery in 2018 at a specific hospital in Milan and then went to its rehabilitation unit. Researchers will use your medical records to build and test a tool that predicts recovery after joint replacement.
MilanAges 18 years+ - NCT07316933Recruiting
Exercise with light blood flow restriction before knee replacement
This trial tests if a specific type of exercise, done with a cuff that lightly restricts blood flow to your leg, can help you get stronger and recover better while you wait for knee replacement surgery. The blood flow restriction is carefully controlled and adjusted during exercise, which may make the workout more effective.
Valencia, ValenciaAges 50–85 - NCT07339137Recruiting
PRP injections for chronic knee osteoarthritis
This trial tests if platelet-rich plasma (PRP) injections into and around the knee joint can reduce pain and improve function for people with moderate knee osteoarthritis who haven't gotten relief from other treatments.
Ankara, ÇankayaAges 40–65 - NCT07347028Recruiting
Trigger point injections for knee osteoarthritis pain
This trial tests whether injecting medication into muscle knots (trigger points) can reduce knee pain in people with knee osteoarthritis. It may be an option if other treatments haven't helped enough.
Beijing, Beijing MunicipalityAges 45 years+ - NCT07386600Recruiting
Comparing two drugs for knee replacement pain relief
This trial tests two different drugs (dexamethasone and dexmedetomidine) added to a standard nerve block for knee replacement. It aims to see which one provides better pain control after surgery.
PoznanAges 65–100 - NCT02993029Recruiting
Fluoride scan–guided treatment for painful knee arthritis
This trial studies a targeted treatment using a fluoride-related injection to help reduce pain from knee osteoarthritis. To join, you need a painful osteoarthritis knee and a specific bone-scan finding (SUV above 10) on an imaging test.
Shanghai, Shanghai MunicipalityAges 40 years+ - NCT07618403Recruiting
Physical Therapy for Knee Arthritis
This study tests whether a structured physical therapy program helps knee arthritis pain and function. Researchers will also look at how your expectations about treatment affect your results.
Ankara, YenimahalleAges 50 years+ - NCT06469177Enrolling by invitation
Pain management app study for joint replacement recovery
This study tests a smartphone tool to help manage pain after hip, knee, or shoulder replacement. It aims to see if using the tool improves your recovery compared to standard care.
Dartmouth, Nova ScotiaAges 19 years+ - NCT05752032Enrolling by invitation
Long-term follow-up after ICM-203 or placebo treatment
This study checks on people who previously received ICM-203 or a matching placebo. It helps researchers understand the longer-term safety and effects of the treatment over time.
Adelaide, South AustraliaAges 50–80 - NCT04660955Enrolling by invitation
10-year follow-up MRI after ACL surgery in young athletes
This study uses an MRI scan to look at knees 10 years after ACL reconstruction. It helps researchers understand how the knee changes over time after sports-related ACL injury, and how well reconstruction lasts.
Cleveland, OhioAges 22–45 - NCT07727551Recruiting
Nerve block before knee replacement for better recovery
This trial tests if a nerve block given a few weeks before knee replacement surgery can improve pain and function after the operation. It is designed for people who have certain risk factors that might make recovery harder.
BrusselsAges 18–60 - NCT07377669Enrolling by invitation
Partial knee replacement plus ACL repair study
This study tests a combination surgery: repairing the torn ACL at the same time as replacing only the damaged part of your knee. It's designed for active people with arthritis in one knee compartment and a fully torn ACL.
BolognaAges 18–75 - NCT06328062Recruiting
Comparing two pain medicines for knee replacement
This study compares two medicines, mirogabalin and pregabalin, to see which works better for pain after total knee replacement. It may help you find more effective pain relief after surgery.
Khlong Luang, Changwat Pathum ThaniAges 50–85 - NCT06311513RecruitingPhase 4
Concentrated bone marrow injection during repeat ACL surgery
This study tests whether adding a concentrated bone marrow injection during repeat ACL surgery helps healing and recovery better than surgery alone. If you have had a previous ACL reconstruction that failed, you may be eligible.
Atlanta, GeorgiaAges 18–55 - NCT06687109Recruiting
Joint replacement surgery registry study
This study collects information from people having joint replacement surgery to track how they do over time and improve care.
Spokane, WashingtonAges 18 years+ - NCT06787417RecruitingPhase 4
Knee alignment study for total knee replacement
This study compares two different surgical techniques for total knee replacement to see which one leads to better knee movement and function. If you need a knee replacement due to arthritis, this trial may help find the best approach for your surgery.
Hamilton, OntarioAges 18 years+ - NCT07079254Recruiting
Meniscus repair vs. partial removal for bucket-handle tears
This trial compares two surgeries for a specific type of meniscus tear that blocks knee straightening: repairing the torn meniscus versus removing the damaged part. The goal is to see which leads to better recovery.
Hässleholm, Skåne CountyAges 15 years+ - NCT04816773Enrolling by invitation
Long-term follow-up for specific knee replacement parts
This study follows people for up to 10 years after a knee replacement done with specific manufacturer parts. It helps the company and doctors understand how well these knee implants work and whether they cause any long-term problems.
Fremont, CaliforniaAges 21 years+ - NCT06231758RecruitingPhase 3
Metformin for knee osteoarthritis: a phase 3 trial
This study tests whether metformin, a common diabetes medication, can help reduce pain and improve knee function in people with knee osteoarthritis. It may offer a new treatment option for those with moderate knee OA.
Damietta, New DamiettaAges 30–60 - NCT05985785Recruiting
Bone Marrow vs Steroid Injection for Knee Arthritis
This study compares two different knee injections—one using your own concentrated bone marrow cells (BMAC) and the other using a steroid (cortisone)—to see which works better for long-term knee pain from osteoarthritis.
Chicago, IllinoisAges 18–70 - NCT06426251Recruiting
Light therapy for knee replacement recovery
This trial tests whether a special light therapy (photobiomodulation) can help reduce pain and speed healing after total knee replacement. If you're having knee replacement and don't have complications like infection or open wounds, you may be eligible.
HsinchuAges 20 years+
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Common questions
- Are there clinical trials for osteoarthritis knees both?
- Yes. Clin2 currently lists 395 recruiting osteoarthritis knees both studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a osteoarthritis knees both trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a osteoarthritis knees both trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.