Clinical trials
Osteoarthritis clinical trials
Below are recruiting osteoarthritis clinical trials, each written for real people, not researchers. We’re tracking 592 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07180979RecruitingPhase 4
Nerve blocks for pain relief after hip replacement
This trial compares three types of nerve blocks to find which provides the best pain relief after a hip replacement. It may help you have less pain and a smoother recovery.
PoznanAges 65–100 - NCT07173335Recruiting
Healthy lifestyle and pain care for rural residents
This trial tests a program that combines healthy lifestyle coaching with pain management for people living in rural areas who have chronic joint or back pain. It aims to help you feel better and move easier by addressing both pain and habits like diet, exercise, sleep, and smoking.
Coffs Harbour, New South WalesAges 18 years+ - NCT07151417RecruitingPhase 2/Phase 3
Steroid injection during total knee replacement
This study tests whether adding a corticosteroid (a type of anti-inflammatory medicine) to the standard pain injection during total knee replacement can improve pain relief. It is for adults getting their first knee replacement at certain military hospitals.
Bethesda, MarylandAges 18 years+ - NCT07150221Enrolling by invitation
10-year follow-up of vitamin E hip liner
This study follows people who received a special vitamin E infused plastic hip liner (Vivacit-E) during a first-time total hip replacement about 10 years ago. It checks how the implant is holding up over time.
South Bend, IndianaAges 18 years+ - NCT06787417RecruitingPhase 4
Knee alignment study for total knee replacement
This study compares two different surgical techniques for total knee replacement to see which one leads to better knee movement and function. If you need a knee replacement due to arthritis, this trial may help find the best approach for your surgery.
Hamilton, OntarioAges 18 years+ - NCT06693479Recruiting
Using a feedback device to help manage shoulder pain at work
This study tests whether a feedback device can help people with work-related shoulder pain manage their symptoms. You may qualify if you have shoulder pain from rotator cuff issues, arthritis, or rheumatoid arthritis and work full-time.
Québec, QuebecAges 18 years+ - NCT07118501Recruiting
Study of the Incompass total ankle system
This study is testing a new ankle replacement device called Incompass. It aims to see how well the device works and how safe it is for people who need ankle replacement surgery.
Morton Grove, IllinoisAges 21 years+ - NCT07104084Recruiting
Antiseptic wash and wound healing after hip replacement
This study tests whether using a special antiseptic wash during hip replacement surgery affects how well the wound heals. It may help doctors choose safer ways to clean the skin before your operation.
Monroeville, PennsylvaniaAges 18 years+ - NCT07105657Recruiting
Rehabilitation after hip or knee replacement
This trial tests if three weeks of intensive rehabilitation helps people who still have physical problems after a total hip or knee replacement. It aims to improve your recovery and function.
BrædstrupAges 18 years+ - NCT06108934Recruiting
Study of the Insignia Hip Stem for First Hip Replacement
This study tests a new cementless hip stem (Insignia) for people having their first total hip replacement. It aims to see how long the implant lasts and how well your hip works after surgery.
Subiaco, Western AustraliaAges 18 years+ - NCT07089251RecruitingPhase 4
Epinephrine and tranexamic acid in knee replacement surgery
This study tests if using epinephrine and tranexamic acid together helps reduce bleeding and improve outcomes during knee replacement surgery. It may be a good fit if you are planning to have knee replacement and do not have certain medical conditions or allergies to these medicines.
Riyadh, Riyadh RegionAges 18–70 - NCT07080814Recruiting
Balance exercises after knee replacement
This study tests whether special balance exercises on a platform can help people who have recently had a knee replacement walk better and feel steadier.
Ankara, YenimahalleAges 18 years+ - NCT07079254Recruiting
Meniscus repair vs. partial removal for bucket-handle tears
This trial compares two surgeries for a specific type of meniscus tear that blocks knee straightening: repairing the torn meniscus versus removing the damaged part. The goal is to see which leads to better recovery.
Hässleholm, Skåne CountyAges 15 years+ - NCT06383936Recruiting
Knee replacement for active sports lovers
This study tests a new knee replacement designed for active people ages 40 to 65 who used to play sports but had to stop due to knee pain. It aims to see if the implant helps you return to your favorite activities.
BolognaAges 40–65 - NCT06616896Recruiting
Vibration exercise for knee osteoarthritis
This study tests whether a special vibrating exercise program can improve knee pain and function in people with knee osteoarthritis. It compares this new rehab approach to standard exercise.
TaipeiAges 50–80 - NCT07058623Recruiting
Nurse-led telehealth vs in-person follow-up after knee replacement
This trial compares follow-up care with a nurse via video calls or phone versus in-person visits after your first total knee replacement. It aims to see if telehealth is as good as in-person for your recovery.
Hong KongAges 18 years+ - NCT04375280Recruiting
Study of mobility problems in people with long-term illnesses
This study observes how people with chronic health conditions affect their ability to move and do everyday activities. It may help researchers better understand mobility limits and what factors influence them.
Clermont-FerrandAges 18–90 - NCT07040878Recruiting
Antigravity treadmill after hip or knee replacement
This study tests whether walking on a special antigravity treadmill (which reduces weight on your joints) helps people recover faster after hip or knee replacement surgery. It's designed for people who are 60 or older and can walk on their own.
Trzebnica, Lower Silesian VoivodeshipAges 60–75 - NCT06994546Recruiting
ArtiBest injection for knee osteoarthritis pain
This trial tests a new hyaluronic acid injection called ArtiBest for people with mild to moderate knee osteoarthritis who haven't gotten enough relief from other treatments like physical therapy or pain pills. It aims to see if the injection can reduce knee pain and improve function.
Kaohsiung CityAges 35–85 - NCT07016672Recruiting
PRP vs. hyaluronic acid for advanced knee arthritis
This study compares two treatments—platelet-rich plasma (PRP) and hyaluronic acid (a lubricating injection)—for people with severe knee arthritis seen on MRI. The goal is to see which better reduces pain.
Toulon, VarAges 18 years+ - NCT07023185Recruiting
Cold and compression after knee replacement
This study will test if adding cold and compression therapy after knee replacement surgery can help with pain, swelling, and recovery. You may qualify if you are 50 or older and having a knee replacement with a specific surgeon.
New Orleans, LouisianaAges 50 years+ - NCT07006883Recruiting
Yoga program for knee osteoarthritis
This trial tests whether a yoga program can improve daily function in people with knee osteoarthritis. It may help reduce pain and stiffness while improving mobility.
São PauloAges 40–80 - NCT06239649Recruiting
Nerve block before knee replacement for faster recovery
This trial tests whether a numbing injection (nerve block) around the knee before surgery can help you recover faster and feel less pain after a total knee replacement. It is for people with knee osteoarthritis who are ready for their first knee replacement surgery.
Denizli, PamukkaleAges 40–85 - NCT06976138Recruiting
Using Light or ions to Improve Sleep and Pain After Knee Surgery
This study tests whether a special bright light or negative ion therapy can help older adults sleep better and have less pain after knee replacement surgery. It's for people with knee arthritis who already have trouble sleeping and are scheduled for one knee replacement.
Baltimore, MarylandAges 60 years+
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Common questions
- Are there clinical trials for osteoarthritis?
- Yes. Clin2 currently lists 592 recruiting osteoarthritis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a osteoarthritis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a osteoarthritis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.