Clinical trials
Osteoarthritis clinical trials
Below are recruiting osteoarthritis clinical trials, each written for real people, not researchers. We’re tracking 610 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06221709Recruiting
Radiofrequency for hip arthritis pain: a clinical trial
This trial tests whether a treatment called continuous radiofrequency can reduce pain from hip arthritis. It is for people with moderate arthritis in one hip who have had pain for more than six months.
Brasília, Federal DistrictAges 18 years+ - NCT06224959Recruiting
Migraine and nerve pain in osteoarthritis study
This study looks at whether people with osteoarthritis also have migraine headaches or nerve pain. Researchers want to better understand these connections to improve treatment.
Clermont-Ferrand, FranceAges 18 years+ - NCT06228573Recruiting
Brain stimulation and yoga for knee pain
This study combines a gentle brain stimulation technique (tDCS) with yoga to see if it helps reduce knee pain and improve movement in people with knee osteoarthritis.
Hamilton, OntarioAges 45 years+ - NCT06237153RecruitingPhase 2
Steroid injection for thumb arthritis pain
This study tests a long-acting steroid injection for thumb arthritis at the base of the thumb. It aims to reduce pain and improve function in people with mild to moderate joint damage.
Stony Brook, New YorkAges 18 years+ - NCT06245109RecruitingPhase 4
Pain medicine study for knee osteoarthritis
This study tests how well different pain medicines work for knee osteoarthritis and looks at brain patterns to understand why some people get more relief. It may help you find a treatment that works best for you.
Chicago, IllinoisAges 41 years+ - NCT06251167Recruiting
Shoe insoles for knee osteoarthritis
This study tests whether shoe insoles can help people with knee osteoarthritis. You might be eligible if you have had knee pain for at least 6 months, your pain is at least moderate, and you also have pain in the same foot.
Vancouver, British ColumbiaAges 50 years+ - NCT06357741Recruiting
Desuzumab for knee osteoarthritis
This study tests a new medicine called Desuzumab for knee osteoarthritis. It looks at whether the medicine can help reduce pain and improve joint function.
Wuhan, HubeiAges 45–75 - NCT06370312Recruiting
Biomarkers for thumb osteoarthritis surgery
This study looks at joint fluid and tissue samples from people with thumb base osteoarthritis who are already scheduled for a surgery called trapeziectomy. The goal is to find markers that might help better understand the disease and improve treatment.
Malmö, Skåne CountyAges 25 years+ - NCT06385028Recruiting
Physical activity program for osteoarthritis patients
This trial tests whether a digital program encouraging physical activity can help people with osteoarthritis feel better and move easier. If you live or work in Luxembourg, you may be able to join.
StrassenAges 18 years+ - NCT06384898Recruiting
Remote Tai Chi for Knee Osteoarthritis
This study tests whether doing Tai Chi (a gentle exercise) remotely from home, twice a week for 12 weeks, can help reduce knee pain and improve function in people with knee osteoarthritis. You would be assigned to either the Tai Chi group or a routine care group that avoids Tai Chi during the study.
Boston, MassachusettsAges 50–100 - NCT06391554Recruiting
Education and exercise for hip osteoarthritis
This study compares the effects of adding exercise to an education program for people with hip osteoarthritis. It aims to see if exercise improves pain, function, and hip joint health (measured by MRI) more than education alone.
Aarhus CAges 45 years+ - NCT06414473RecruitingPhase 1/Phase 2
CBD for knee osteoarthritis pain
This study tests whether a CBD (cannabidiol) product can help reduce pain and improve daily life for people with knee osteoarthritis. If you have moderate to severe knee pain and haven't used cannabis recently, you may be able to join.
Gainesville, FloridaAges 40–75 - NCT06444919RecruitingPhase 4
Capsaicin patch for finger osteoarthritis with nerve pain
This study tests if a capsaicin patch (a hot pepper extract) can reduce finger pain in people with osteoarthritis who also have nerve-like pain. It's for those who haven't gotten enough relief from standard painkillers.
Clermont-FerrandAges 18 years+ - NCT06463847RecruitingPhase 1
Stem cell therapy for knee osteoarthritis
This trial tests a new stem cell treatment (UC-MSCs) for knee osteoarthritis. It aims to see if this treatment is safe and can help reduce pain and improve knee function.
Wuhan, HubeiAges 50–70 - NCT06466850Recruiting
Stem cell exosomes for knee osteoarthritis
This trial studies whether a natural substance called exosomes, derived from stem cells, can help reduce pain and improve function in people with knee osteoarthritis. It may be an option if other treatments have not worked well for you.
IsfahanAges 45–75 - NCT06478186RecruitingPhase 4
Knee Osteoarthritis Steroid Injection Study for People with Type 2 Diabetes
This study compares two different steroid knee injections—Zilretta and Kenalog—to see which works better for people with both knee osteoarthritis and type 2 diabetes. It uses a continuous glucose monitor to track blood sugar changes.
Kansas City, KansasAges 40 years+ - NCT06483269Recruiting
Platelet-rich plasma injection for knee arthritis in young athletes
This trial tests using your own platelet-rich plasma (PRP), made from a blood sample, as an injection to treat knee osteoarthritis in active young adults. The goal is to see if it reduces pain and helps you stay active.
BolognaAges 18–40 - NCT06485843RecruitingPhase 2
Testing a new injection for moderate to severe knee osteoarthritis
This study tests the safety of an experimental injection called OA-SYS for people with moderate to severe knee osteoarthritis. It may help if you have not had recent injections or certain other health problems.
Las Vegas, NevadaAges 35–75 - NCT06549686RecruitingPhase 3
Knee osteoarthritis treatment study with cell therapy
This trial tests a new cell-based treatment (CLS2901C) for knee osteoarthritis. It combines the treatment with a realignment surgery (proximal tibial osteotomy) to help repair cartilage damage and reduce pain.
Ebina, KanagawaAges 20–79 - NCT06497140RecruitingPhase 3
Genicular artery embolization for painful knee osteoarthritis
This trial tests a new procedure called genicular artery embolization to treat knee pain from osteoarthritis. If you have moderate to severe knee pain and are not a candidate for knee replacement or other surgery, this treatment may help reduce pain and improve function.
ParisAges 40–90 - NCT06502587Recruiting
Blood flow restriction with low-intensity exercises for knee osteoarthritis
This study tests if using a special cuff to slightly reduce blood flow while doing gentle exercises can help reduce knee pain and improve function in people with knee osteoarthritis. It may offer a way to get stronger without heavy weights.
Lahore, Punjab ProvinceAges 40–65 - NCT06511557Recruiting
Virtual reality vs. leg exercises for knee arthritis
This study compares virtual reality exercises with standard leg-strengthening moves to see which better reduces pain and improves function in people with knee osteoarthritis (OA).
Rawalpindi, Punjab ProvinceAges 50 years+ - NCT06514716Recruiting
Steroid shot vs. standard procedure for knee arthritis
This study tests whether a corticosteroid shot (a strong anti-inflammatory medicine) into the knee joint works better than the standard GAE procedure for people with knee osteoarthritis. It aims to see which approach provides better pain relief and function.
ZagazigAges 18–80 - NCT06514703Recruiting
CT vs. X-ray Guided Nerve Ablation for Knee Arthritis
This study compares two different image-guided techniques (CT scan vs. fluoroscopy) to perform a nerve ablation procedure that blocks pain signals from the knee. It aims to find which method works better for reducing pain in people with knee osteoarthritis.
Zagazig, Sharqia ProvinceAges 45–80
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Common questions
- Are there clinical trials for osteoarthritis?
- Yes. Clin2 currently lists 610 recruiting osteoarthritis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a osteoarthritis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a osteoarthritis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.