Clinical trials · North Carolina
Overweight or Obesity clinical trials in North Carolina
We’re tracking 65 recruiting overweight or obesity studies with a site in North Carolina — including Phase 1, Phase 1/Phase 2, Phase 2 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies in North Carolina
- NCT07225686RecruitingPhase 3
Maridebart Cafraglutide for sleep apnea in adults on CPAP
This study is testing whether a new medicine, called Maridebart Cafraglutide, can help people with obstructive sleep apnea who are already using a CPAP machine. The medicine may help with weight loss and potentially improve sleep apnea. Participants will either receive the medicine or a placebo (an inactive substance), and the study lasts for several months.
Monroe, North CarolinaAges 18–99 - NCT04328337RecruitingPhase 1/Phase 2
Study tests how rising fatty acids affect brain fuel use
This early-phase study will raise fatty acid levels temporarily and see how the brain uses glucose (sugar) and processes energy. It may help researchers understand how metabolism in the body can change brain function.
Chapel Hill, North CarolinaAges 18–45 - NCT04752293Recruiting
Study of a kidney blood-pressure system in kids
This study looks at how a kidney-related blood-pressure system works in children and teenagers, comparing those with newly diagnosed primary (no known cause) high blood pressure to those with normal blood pressure. It may help doctors better understand childhood blood-pressure changes and guide future care.
Winston-Salem, North CarolinaAges 7–18 - NCT05082519RecruitingPhase 2
Calorie reduction and activity to help chemo work in B-ALL
This Phase 2 study tests whether eating fewer calories and doing activity safely can make chemotherapy work better for children and young adults with newly diagnosed B-ALL. It aims to reduce chemo resistance, meaning help leukemia respond more strongly to treatment.
Charlotte, North CarolinaAges 10–25 - NCT05542407RecruitingPhase 1
ONC201 plus atezolizumab for endometrial cancer and obesity
This Phase 1 study tests ONC201 together with atezolizumab in people with metastatic or returning endometrial cancer, especially when obesity may be driving the cancer. It aims to find a safe dose and see whether the combination can slow the cancer’s growth.
Chapel Hill, North CarolinaAges 18 years+ - NCT05656807Recruiting
Weight management program for child care staff and families
This study tests a weight management program delivered through child care centers, involving teachers and parents. It aims to improve healthy habits for children ages 2–5 through changes in the child care setting.
Chapel Hill, North CarolinaAges 2 years+ - NCT06044571Recruiting
Weight loss program for older adults via telehealth
This trial tests a weight loss program delivered through video calls to help adults aged 65-85 with obesity lose weight. It is designed for those with at least two other health conditions and who are ready to make changes.
Chapel Hill, North CarolinaAges 65–85 - NCT06420700Recruiting
Stomach Lining Ablation with Sleeve Gastroplasty for Weight Loss
This study combines two endoscopic procedures to help you lose weight: one that reduces the size of your stomach and one that alters the stomach lining. It is designed for people who are ready to commit to long-term diet changes.
Cary, North CarolinaAges 18–65 - NCT06428617Recruiting
Stomach ablation treatment for weight loss
This trial studies a new stomach procedure called fundus ablation to help with weight loss. The doctor uses a device to treat the upper part of your stomach, and you'll follow a special diet long-term.
Cary, North CarolinaAges 18–65 - NCT06848244Recruiting
Preventing diabetes in young Black women
This trial tests a program to help young Black women with prediabetes and binge eating prevent type 2 diabetes using a smartphone. It focuses on healthy eating and behavior change.
Chapel Hill, North CarolinaAges 18–25 - NCT06848491Recruiting
Mobile health program for weight management in young cancer survivors
This study tests a mobile health program to help young adult cancer survivors (ages 18–39) manage their weight. You'll be randomly assigned to one of two programs that use text messages and other tools to support healthy eating and physical activity.
Chapel Hill, North CarolinaAges 18–39 - NCT06921382Recruiting
Breastfeeding help to prevent childhood obesity
This study offers breastfeeding support to new mothers to help prevent childhood obesity. It is for Hispanic mothers who plan to breastfeed and are eligible for WIC.
Greensboro, North CarolinaAges 5 days+ - NCT07126587Recruiting
Healthy Living in Anson County Study
This study offers healthy meals and group classes to help people in Anson County manage or prevent chronic diseases like diabetes and high blood pressure. You'll learn about and try a Mediterranean diet, which is known to be good for heart health.
Chapel Hill, North CarolinaAges 18–99 - NCT07296861Recruiting
Home program for healthy growth in children with Down syndrome
This study tests a family-based program you can do at home to help your young child with Down syndrome develop healthy habits. It aims to support your child's growth and well-being through fun activities and guidance.
Chapel Hill, North CarolinaAges Any age - NCT07339423RecruitingPhase 3
A study of a new medicine for weight loss
This study tests a new medicine to see how well it helps people with excess body weight lose weight. It may be an option if you have tried to lose weight through dieting before but haven't had lasting success.
Chapel Hill, North CarolinaAges 18 years+ - NCT07481630RecruitingPhase 3
Testing a new medicine for weight loss and knee pain
This study tests if a new medicine called NNC0487-0111 can help people with extra weight and knee osteoarthritis lose weight and reduce knee pain. If you have knee pain most days and are willing to stop pain relievers for short periods, you may be able to join.
Wilmington, North CarolinaAges 18 years+ - NCT07503210RecruitingPhase 3
Study of a new medicine to maintain weight loss
This study tests an investigational medicine to help people who have lost weight keep it off. It's for adults without diabetes who haven't used similar weight-loss drugs before.
Greensboro, North CarolinaAges 18 years+
Overweight or Obesity trials by city in North Carolina
Where these studies are running in North Carolina
Institutions with a site for the recruiting overweight or obesity studies listed above.
- University of North Carolina at Chapel Hill · 3 studies
- Accellacare · 2 studies
- True You Weight Loss · 2 studies
- UNC Center for Health Promotion and Disease Prevention · 2 studies
- Biomedical Research Imaging Center at UNC
- Cone Health Cancer Center
- Levine Children's Hospital
- Medication Management
What taking part in a overweight or obesity study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Overweight or Obesity trials in other states
Common questions
- Are there overweight or obesity clinical trials in North Carolina?
- Yes. We're currently tracking 65 recruiting overweight or obesity studies with a site in North Carolina, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a overweight or obesity study in North Carolina?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in North Carolina to take part?
- Not necessarily. These studies have a site in North Carolina, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a overweight or obesity trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New overweight or obesity studies open in North Carolina regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.