Clinical trials · South Carolina
Overweight or Obesity clinical trials in South Carolina
We’re tracking 48 recruiting overweight or obesity studies with a site in South Carolina — including Phase 1, Phase 1/Phase 2, Phase 2 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies in South Carolina
- NCT07720271RecruitingPhase 3
Zenagamtide weight loss study for adults
This study is testing a new tablet called Zenagamtide to help people with extra body weight lose weight. It's for adults who are not diabetic and haven't used similar weight loss drugs before.
Charleston, South CarolinaAges 18 years+ - NCT07684235RecruitingPhase 3
Long-term study of a weight-loss drug for trial graduates
This study tests a drug called Maridebart Cafraglutide for long-term weight management in people who completed a previous related trial. It looks at how well the drug works and its safety over time.
Greenville, South CarolinaAges 18–99 - NCT07668414RecruitingPhase 3
Study comparing Zenagamtide and Semaglutide for weight loss
This trial tests a new medicine Zenagamtide to see if it helps people with excess weight lose more weight than Semaglutide, an existing weight loss drug. You may join if you are an adult with overweight or obesity but do not have diabetes.
Charleston, South CarolinaAges 18 years+ - NCT07667803RecruitingPhase 3
Study of elecoglipron for weight loss in obesity or overweight
This trial tests an investigational drug called elecoglipron to see if it helps people with obesity or overweight lose weight. It may be an option if you have a high body mass index or weight-related health issues like high blood pressure or prediabetes.
Charleston, South CarolinaAges 18 years+ - NCT07607587RecruitingPhase 1
Testing a new weight-loss drug for people who couldn't tolerate GLP-1 shots
This study tests a new injectable medication called cagrilintide for people with obesity who had to stop GLP-1 drugs (like Ozempic or Wegovy) because of stomach problems. The goal is to see if cagrilintide causes fewer stomach side effects while still helping with weight.
North Charleston, South CarolinaAges 18 years+ - NCT07583459Recruiting
Summer childcare program to prevent unhealthy weight gain in preschoolers
This study tests whether a center-based childcare program during summer can help prevent excessive weight gain in preschool-aged children from low-income families. The program focuses on healthy eating and activity habits during the summer months when children are not in school.
Columbia, South CarolinaAges 3–5 - NCT07571109RecruitingPhase 3
Weight Loss Medicine for Sleep Apnea on CPAP
This study tests a new injectable medicine (NNC0487-0111) to help people lose weight and improve obstructive sleep apnea (a breathing condition during sleep). You must already be using a CPAP machine (positive airway pressure device) for your sleep apnea.
Columbia, South CarolinaAges 18 years+ - NCT07533175RecruitingPhase 3
Testing a new weight-loss medicine for type 2 diabetes
This study tests whether a new medicine called NNC0487-0111 helps people with type 2 diabetes and excess weight lose weight. You'll take the medicine along with your current diabetes care to see if it works better than standard treatment.
Spartanburg, South CarolinaAges 18 years+ - NCT07253285RecruitingPhase 3
Study on cagrilintide and CagriSema for kids with excess weight
This trial tests two new medicines (cagrilintide and CagriSema) to see if they help children and teens lose weight. It's for young people who have tried lifestyle changes without enough success.
North Charleston, South CarolinaAges 8–18 - NCT07140952Recruiting
Heart-healthy diet and exercise for stroke survivors
This study tests a heart-healthy diet and exercise plan for stroke survivors to improve health and fitness. It is done virtually to make it easy to join from home.
Florence, South CarolinaAges 45–80 - NCT07123779RecruitingPhase 1/Phase 2
Study of a new drug for heart failure with pulmonary hypertension
This study tests an investigational drug (HS235) for people who have both heart failure with preserved ejection fraction and a type of pulmonary hypertension that can happen with it. The goal is to see if the drug can improve symptoms and quality of life.
Greenville, South CarolinaAges 18 years+ - NCT06105957Recruiting
Digital weight loss program for rural adults
This study tests a digital weight loss program designed for adults living in rural areas. It uses a smartphone app, website, and video group sessions to help you lose weight through diet and physical activity.
Columbia, South CarolinaAges 18 years+ - NCT07817875RecruitingPhase 3
Tirzepatide for weight loss in children aged 6 to under 12
This study tests a once-weekly medication called tirzepatide to help children aged 6 to under 12 with obesity lose weight. It compares the medication to a placebo (inactive shot) to see if it safely helps with weight loss in this age group.
Charleston, South CarolinaAges 6–11 - NCT07564414RecruitingPhase 3
Weight Loss Study Comparing Two Doses of CagriSema
This study tests whether a new combination medication called CagriSema (in two different doses) helps people with obesity lose weight. You may qualify if you're 18 or older, have a BMI of 35 or higher, and either don't have type 2 diabetes or have it well-controlled.
Spartanburg, South CarolinaAges 18 years+ - NCT07567001RecruitingPhase 3
Testing NNC0487-0111 for Heart Failure and Obesity
This study tests whether a new medication called NNC0487-0111 can help people with heart failure who also have obesity. Researchers will compare it to a placebo (inactive pill) to see if it improves heart function and overall health.
Fort Mill, South CarolinaAges 18 years+ - NCT07518407Recruiting
Nutrition Education and Diet Guidance While Using GLP-1 Medication
This study teaches adults on GLP-1 medication (like Ozempic or Wegovy) how to eat better and lose weight using a smartphone app. Researchers want to see if personalized nutrition advice helps you get better results from your medication.
Columbia, South CarolinaAges 18–65 - NCT07087808Recruiting
Family health program for teens with obesity in rural areas
This trial tests a virtual family intervention to help teens ages 12-17 with obesity and their primary caregiver (who is also overweight) improve health habits together. It's designed for families living in rural communities who both have a smartphone.
Charleston, South CarolinaAges 12–17 - NCT07783802RecruitingPhase 2
Study of clazakizumab for adults with high inflammation and heart risk
This study tests whether clazakizumab can reduce the risk of heart attacks or strokes in people with high levels of inflammation (measured by a blood test called hsCRP) and conditions like heart disease, obesity, diabetes, high blood pressure, or kidney disease. If you qualify, you'll receive either the study drug or a placebo to see if it helps lower your risk.
North Charleston, South CarolinaAges 18 years+ - NCT07481630RecruitingPhase 3
Testing a new medicine for weight loss and knee pain
This study tests if a new medicine called NNC0487-0111 can help people with extra weight and knee osteoarthritis lose weight and reduce knee pain. If you have knee pain most days and are willing to stop pain relievers for short periods, you may be able to join.
North Charleston, South CarolinaAges 18 years+ - NCT07339423RecruitingPhase 3
A study of a new medicine for weight loss
This study tests a new medicine to see how well it helps people with excess body weight lose weight. It may be an option if you have tried to lose weight through dieting before but haven't had lasting success.
Charleston, South CarolinaAges 18 years+ - NCT07282340RecruitingPhase 2
Phentermine for weight loss in teens
This study tests a medicine called phentermine to help teens ages 12 to 17 with obesity lose weight. It will check if the medicine is safe and works well for teenagers.
Columbia, South CarolinaAges 12–17 - NCT07176234Enrolling by invitation
Linking exercise for better stress management in teens
This study tests whether a home-based exercise program can help African American teens (ages 11–16) manage daily stress. It compares the program to a healthy lifestyle education group.
Columbia, South CarolinaAges 11–16 - NCT06888011Recruiting
Healthy living program for rural children
This study tests a program called iAmHealthy to help children ages 6 to 11 who live in rural areas and are overweight. The program will help families make healthy changes at home and in their daily routine.
Charleston, South CarolinaAges 6–11 - NCT05901675Recruiting
Weight loss and exercise after stroke in walking recovery
This trial studies whether a weight-loss plan combined with exercise can improve walking and leg movement after stroke. It may help if you have ongoing leg weakness but can still walk without devices for testing.
Charleston, South CarolinaAges 35–85
Overweight or Obesity trials by city in South Carolina
Where these studies are running in South Carolina
Institutions with a site for the recruiting overweight or obesity studies listed above.
- Coastal Carolina Research Center · 4 studies
- Spartanburg Medical Research · 4 studies
- Hillcrest Clinical Research · 3 studies
- University of South Carolina · 3 studies
- Medical Uni of SC Charleston · 2 studies
- Medical University of South Carolina · 2 studies
- Bogan Sleep Consultants
- Coastal Carolina Res Ctr
What taking part in a overweight or obesity study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Overweight or Obesity trials in other states
Common questions
- Are there overweight or obesity clinical trials in South Carolina?
- Yes. We're currently tracking 48 recruiting overweight or obesity studies with a site in South Carolina, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a overweight or obesity study in South Carolina?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in South Carolina to take part?
- Not necessarily. These studies have a site in South Carolina, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a overweight or obesity trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New overweight or obesity studies open in South Carolina regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.