Clinical trials
Overweight or Obesity clinical trials
Below are recruiting overweight or obesity clinical trials, each written for real people, not researchers. We’re tracking 1,534 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06144593Recruiting
Carb cutting for people with type 2 diabetes
This study looks at whether cutting carbs on certain days can improve metabolism for people with type 2 diabetes. It may help if you have mild to moderate diabetes and are overweight or obese.
HvidovreAges 35–75 - NCT06151015Recruiting
Dietary nitrate and calorie restriction for brain health
This study tests whether eating foods rich in dietary nitrates (like beets) combined with reducing calorie intake improves memory and blood vessel function in older adults.
Nottingham, NottinghamshireAges 60–75 - NCT06173778RecruitingPhase 2
Semaglutide for weight management after quitting smoking
This study tests whether the drug semaglutide (often used for weight loss) can help people who quit smoking avoid gaining weight. It's for people who are overweight or have weight-related health issues and want to stop smoking.
Austin, TexasAges 18–75 - NCT06244888RecruitingPhase 2
Using new strategies to help maintain weight loss
This study tests a method to help people who have already lost weight keep it off. It uses a control systems engineering approach to provide personalized support.
Providence, Rhode IslandAges 18–70 - NCT06277232Recruiting
Nutrition care for chronic pain patients
This trial tests a nutrition care program for people with chronic pain who are also overweight. You will receive support to improve your diet while attending a pain rehabilitation program.
Linköping, Östergötland CountyAges 18 years+ - NCT06323070Recruiting
Watermelon vs. low-fat cookies for wellness
This trial compares eating watermelon or low-fat cookies to see how they affect your overall wellness. It will help determine if one snack is better for your health.
San Diego, CaliforniaAges 18–50 - NCT07332741RecruitingPhase 2
Food as medicine for better blood pressure
This study tests a program that provides healthy food and support to help people with high blood pressure and a BMI of 30 or higher eat better and control their blood pressure. If you join, you'll get guidance on the DASH diet (a heart-healthy eating plan) and text messages to help you stay on track.
Chicago, IllinoisAges Any age - NCT06354088RecruitingPhase 1
Study of alpelisib for insulin resistance
This study tests a single dose of a drug called alpelisib (a PI3K inhibitor) to see how it affects insulin and blood sugar in people who are either insulin sensitive or insulin resistant. The goal is to understand why some people become resistant to insulin, which may help find new treatments for diabetes and related conditions.
New York, New YorkAges 18–70 - NCT06366399Recruiting
Timing of resistance exercise for weight management
This study tests if doing resistance exercises (like lifting weights) in the morning or afternoon is better for weight management. You may qualify if you are between 50 and 74 years old, are overweight but generally healthy, and have not been very active with strength training.
Salt Lake City, UtahAges 50–74 - NCT06370845RecruitingEarly Phase 1
Smell test to find natural odor in spinal fluid
This study investigates whether a natural smell can be detected in the fluid around your brain and spine (cerebrospinal fluid) after you sniff it. It aims to understand how smells enter the brain in people with different body weights who are already scheduled for a routine spinal tap.
BaselAges 18–60 - NCT06382298Recruiting
Cottonseed oil vs. similar oil for heart health
This study compares the effects of cottonseed oil versus a similar oil on heart health. It is for people with high cholesterol or who are overweight and want to see if changing cooking oils can improve their cholesterol levels.
Athens, GeorgiaAges 25–75 - NCT06390345Recruiting
Telehealth lifestyle and exercise for COPD and sleep apnea
This study tests a telehealth program that combines lifestyle coaching and exercise to help people with both COPD and sleep apnea improve their breathing and daily function. It may be a good fit if you are overweight, have a history of smoking, and feel short of breath during light activity.
Boise, IdahoAges 18 years+ - NCT06426693Recruiting
Brain training for food cravings
This study tests a brain-training technique called neurofeedback to help reduce food cravings. You'll get MRI scans while learning to control brain activity related to cravings.
New Haven, ConnecticutAges 18–60 - NCT06432790Recruiting
In-person vs online healthy living and asthma program for kids
This study compares two programs for helping children with asthma who are overweight or obese — one that is held in person and another that is offered online. It tests whether learning about healthy habits and asthma management works better when done face-to-face or on a computer.
Boston, MassachusettsAges 4–17 - NCT06477705Recruiting
Energy cost of 1-hour football training for men with metabolic syndrome
This trial measures how much energy you burn during one hour of football training. It aims to understand exercise energy use in people with metabolic syndrome, which could help guide future exercise programs.
TrikalaAges 40–60 - NCT06481020Recruiting
Plant sterols for heart health in overweight adults
This study tests whether plant sterols (natural compounds found in plants) can help improve cholesterol and other heart health markers. If you are overweight and have high LDL cholesterol, you may be able to join this study to see if adding plant sterols to your diet helps.
ValenciaAges 18–80 - NCT06595251Recruiting
Fit2Play park study for better health
This trial looks at health programs in Miami-Dade parks. If you are already in the Fit2Play study, your data will be used to learn how these programs help people get healthier.
Miami, FloridaAges 6–14 - NCT05234125Recruiting
Lifestyle counseling during pregnancy for African American women
This trial tests a better lifestyle counseling program during pregnancy to help improve health—especially for women who started pregnancy at a higher weight. It may help you learn practical changes for a healthier pregnancy and outcomes.
Chicago, IllinoisAges 18–40 - NCT07692438Recruiting
Can Taiwan green propolis help with fatty liver and body fat?
This trial tests whether a natural supplement called Taiwan green propolis can improve blood fats and reduce body fat in people with fatty liver disease (MASLD). If you have fatty liver plus at least one related health issue like high cholesterol, diabetes, or high blood pressure, you may be eligible.
DalinAges 18–80 - NCT06487832Recruiting
Effect of diabetes drug on brain response to insulin
This study tests whether a GLP-1 receptor agonist (a type of diabetes medicine) changes how the brain responds to insulin in people with different body sizes. It may help understand if this drug can improve brain function related to insulin.
TübingenAges 18–70 - NCT06491537Recruiting
Time-restricted eating for losing weight after having a baby
This study tests whether eating only during a specific daily window (time-restricted eating) helps new moms lose weight. It may be an option if you are 6 to 16 weeks postpartum and have a body mass index (BMI) of 25 or higher.
Birmingham, AlabamaAges 18 years+ - NCT06493084RecruitingPhase 1
Testing LAE102 in healthy and overweight adults
This study tests a new medicine called LAE102 in two groups: healthy volunteers and people who are overweight or obese. The goal is to see if it is safe and how the body processes it.
Shanghai, Shanghai MunicipalityAges 18–65 - NCT06497946Recruiting
SlimTrack app for weight and heart health in menopause
This trial tests if a smartphone platform called SlimTrack® helps postmenopausal women stick to a diet, lose weight, and improve artery health. You may qualify if you are postmenopausal, overweight or obese, and not very active.
Porto Alegre, Rio Grande do SulAges 45–60 - NCT06499857RecruitingPhase 3
Semaglutide for atrial fibrillation and weight loss
This study tests whether a weekly injection of semaglutide (the same drug in Wegovy and Ozempic) can help people with atrial fibrillation lose weight and improve their heart condition. It's for people with AF who also have obesity, and may or may not plan to have a heart procedure called catheter ablation.
Phoenix, ArizonaAges 18–75
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Common questions
- Are there clinical trials for overweight or obesity?
- Yes. Clin2 currently lists 1,534 recruiting overweight or obesity studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a overweight or obesity trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a overweight or obesity trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.