Clinical trials
Overweight or Obesity clinical trials
Below are recruiting overweight or obesity clinical trials, each written for real people, not researchers. We’re tracking 1,536 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04934228RecruitingPhase 1
Study targeting inflammation in people with obesity and high blood pressure
This Phase 1 study looks at a treatment aimed at reducing “inflammation patterns” that are common in obesity and insulin resistance. If you meet specific health and lab criteria, you may be asked to visit a research lab and provide blood samples to see how the treatment affects your body.
Kansas City, KansasAges 18–79 - NCT04942093Recruiting
High-protein low-calorie diet before weight-loss surgery
This trial studies whether a higher-protein, lower-calorie diet before sleeve gastrectomy (a type of weight-loss surgery) changes outcomes after surgery. You may be able to join if you’re scheduled for the operation and meet specific health and safety requirements.
DieppeAges 18–65 - NCT04990024Recruiting
Diet trial for people with obesity using semaglutide
This study compares different diets to see how they affect “arterial stiffness” (how hard the blood vessels are) in people with obesity who are starting semaglutide for weight management. It may help find a diet approach that improves heart and blood-vessel health while you use semaglutide.
Beirut, Riad El SolhAges 18–49 - NCT05028309Recruiting
Study how obesity affects breathing and exercise in older adults
This study compares how body weight (higher or lower body fat) affects lung function, breathing during exercise, and exercise capacity in adults ages 65–75. You may be asked to do lung and exercise testing, but only if you meet health and activity restrictions.
Dallas, TexasAges 65–75 - NCT05028205Recruiting
Fruit and vegetable voucher program for kids
This trial tests whether giving families vouchers for fruits and vegetables helps improve children’s eating and health. It focuses on children ages 4–10 who have higher body weight for their age and who can participate with an adult caregiver.
Knoxville, TennesseeAges 4–10 - NCT05077579Recruiting
Alzheimer’s scan study for people with higher body weight
This study uses brain scans (MRI and two special PET scans) to see how Alzheimer’s-related changes show up in people who are overweight or obese, with different blood-sugar and insulin patterns. It may help researchers understand whether body weight and metabolism affect early Alzheimer’s markers in the brain.
St Louis, MissouriAges 40–60 - NCT05120492Recruiting
Program for severe knee arthritis and extreme weight
This feasibility study tests a practical approach to help people with very severe knee arthritis and very high body weight. It aims to find an effective and safe way to manage both conditions together in real-world care.
Halifax, Nova ScotiaAges 18–65 - NCT05125822Recruiting
Study of how bodies change weight in youth with obesity
This study looks at what helps or drives weight changes in children and teens with obesity. You may be asked about growth and body changes to better understand why weight changes happen and how to manage them.
Chicago, IllinoisAges 11–15 - NCT05143697Recruiting
Coaching program to help young children reduce excess weight
This trial tests a family wellness coaching program using motivational interview counseling and referrals. It may help families support healthier habits for children ages 2 to 8 who have weight above a recommended range.
Pasadena, CaliforniaAges 2–8 - NCT05165706Recruiting
Study of how obesity affects insulin resistance over time
This study follows adults over time to understand how weight and body chemistry relate to insulin resistance. It may help researchers learn why insulin resistance happens and what could prevent or improve it.
Stanford, CaliforniaAges 35–65 - NCT05223530Recruiting
Study of how pregnancy programs future child health
This study follows mothers who previously joined two specific pregnancy research programs, to understand why some children may be more likely to develop weight and heart-related health problems later. If you were part of those original studies, your information could help researchers look for early predictors and prevention ideas.
HelsinkiAges 11–55 - NCT05225233Recruiting
Brain stimulation plus training to help reduce impulsive eating and weight
This study tests whether a brain stimulation method (tDCS) combined with cognitive training can reduce impulsivity around food and improve weight in Veterans with obesity. You would join a MOVE! weight program and complete study procedures to see whether this approach helps.
Minneapolis, MinnesotaAges 18–80 - NCT05237089Recruiting
Electroacupuncture for weight loss in people with prediabetes
This trial studies whether electroacupuncture can help reduce weight in adults who have obesity and blood sugar levels in the prediabetes range. You might be eligible if your weight has been stable and you don’t have certain medical or skin problems.
Shanghai, Shanghai MunicipalityAges 18–65 - NCT05237440Recruiting
Childhood trauma and stress hormones in women with obesity
This study looks at how childhood trauma might affect stress hormones (cortisol) and inflammation in women with obesity. It aims to find connections that could lead to better treatments.
LimogesAges 18 years+ - NCT05242835Recruiting
Study for weight regain after sleeve stomach surgery
This trial studies a specific type of metabolic (weight-related) surgery for people whose sleeve gastrectomy did not lead to enough weight loss or has caused significant weight regain. It may help improve long-term weight and related health problems.
Québec, QuebecAges 18–60 - NCT05277532Recruiting
Exercise and sleep timing for overweight type 1 diabetes
This trial studies whether changing daily sleep timing (circadian rhythm) and doing physical exercise can improve health outcomes in people who are overweight and have type 1 diabetes (or in some healthy people). It may help by seeing what combinations of routine and activity are most beneficial.
StockholmAges 18–50 - NCT05277714Recruiting
Neurofeedback for food addiction in people with obesity
This trial tests whether brain-training feedback using near-infrared sensors (a painless light-based brain measure) can reduce food addiction behaviors in people with obesity. If you qualify for obesity surgery and have food addiction signs, you may be offered this therapy and monitored during the study.
RennesAges 18–55 - NCT05281016Recruiting
Online family program to help children with weight
This study tests an online, family-based program (called the LITE Programme) to help children who are overweight. It may help improve healthy habits at home and support weight management.
SingaporeAges 6–12 - NCT05312892RecruitingPhase 1/Phase 2
Study for weight-related hormone signals in people with high blood pressure
This early-phase study looks at how the body’s “fight-or-flight” signals may be involved in weight gain (obesity) and high blood pressure. It may help researchers understand the biology and guide future treatments.
Nashville, TennesseeAges 18–65 - NCT05326477Recruiting
Study factors that predict how well behavioral weight plans work
This study looks at which personal and health factors help or hurt how well behavioral obesity treatments work. It may help doctors better tailor weight-treatment plans for people with obesity.
Chicago, IllinoisAges 18 years+ - NCT05364957Recruiting
Gastric balloon plus asthma care for uncontrolled asthma and obesity
This study tests whether placing a soft “balloon” inside the stomach (intragastric balloon) can help people who have uncontrolled asthma and obesity. It also checks whether the balloon is safe and can improve asthma control when standard inhaler treatment is already in use.
Toulouse, OccitanieAges 18–65 - NCT05419726Recruiting
Semaglutide study to see how brown fat responds in weight loss
This trial studies how brown fat (a type of body fat) changes after starting semaglutide for weight loss. You may help researchers understand how this medication affects the body’s energy use, which could improve weight-loss treatments.
Los Angeles, CaliforniaAges 18 years+ - NCT05477212Recruiting
Study gut leakiness in obesity and fatty liver with a ketogenic diet
This study looks at “gut permeability,” sometimes called intestinal leakiness, in people with obesity and fatty liver disease. It tests whether a ketogenic (very low-carb) diet changes gut leakiness and fatty liver measurements.
Castellana Grotte, BARIAges 18–65 - NCT05494138Recruiting
AI-based nutrition study for adults with obesity and normal weight
This study uses nutrition information and artificial intelligence to better understand diet patterns in adults with obesity and in adults with normal weight. Your results may help researchers design better nutrition guidance for people with obesity and related health risks.
SeoulAges 19 years+
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Common questions
- Are there clinical trials for overweight or obesity?
- Yes. Clin2 currently lists 1,536 recruiting overweight or obesity studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a overweight or obesity trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a overweight or obesity trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.