Clinical trials
Pain After Surgery clinical trials
Below are recruiting pain after surgery clinical trials, each written for real people, not researchers. We’re tracking 420 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06443164Enrolling by invitation
Chronic Pain Treatment Before Gender-Affirming Surgery
This study tests a one-session pain management class called Empowered Relief for people with chronic pain who are planning gender-affirming surgery. The goal is to see if learning these skills before surgery helps with pain afterward.
Portland, OregonAges 18–100 - NCT03675386Recruiting
Help reducing opioid use after surgery for chronic pain
This trial tests a program to help people with long-term (chronic) pain use less opioid medicine after surgery. It may help you reduce opioid doses while still managing your pain.
Toronto, OntarioAges 18 years+ - NCT04811209Recruiting
Testing better pain control and recovery after orthopedic surgery
This trial looks at how well a pain-control plan works after certain orthopedic surgeries and how it affects recovery and patient-reported outcomes. It may help determine what level of pain relief is meaningful to patients after surgery.
Toronto, OntarioAges 18–80 - NCT07455565Recruiting
Pain monitoring with ANI after lumbar spine surgery
This study tests a new way to monitor pain after lower back surgery using a device called ANI, which tracks your body's response to pain. The goal is to see if this method helps doctors give you better pain relief.
Antalya, AntalyaAges 18–65 - NCT05877157Recruiting
Study how pain and opioids change after surgery
This study follows adults in the hospital after surgery to understand how pain and opioid (strong pain medicine) use affect them. Your answers on questionnaires help researchers see what happens after different types of anesthesia.
Zagreb, Vinogradska 29Ages 18 years+ - NCT07448246Recruiting
Rhomboid block for pain after breast implant surgery
This trial tests if a specific nerve block (rhomboid intercostal block) can reduce pain after breast implant surgery. If you are having bilateral breast implants and are in good general health, you may be eligible.
Aydin, EfelerAges 18–65 - NCT06710405RecruitingPhase 4
Lidocaine for pain relief after children's chest surgery
This trial tests whether giving lidocaine during surgery can reduce pain and speed up recovery in children under 7 having chest surgery with a camera. If it works, it could mean less pain and a faster return to normal after the operation.
SeoulAges 6 months–7 years - NCT05306665Recruiting
Preventing pain after spine surgery
This study looks at ways to reduce pain after certain spine surgeries. If you’re having one of these procedures, you may be invited to try a pain-prevention approach and help researchers understand what works best.
Chestnut Hill, MassachusettsAges 22 years+ - NCT07109557Recruiting
Baduanjin for recovery after knee replacement
This study tests whether doing Baduanjin, a gentle mind-body exercise, helps people recover better after knee replacement surgery. It focuses on patients who are in stable condition and willing to try the exercise.
YalovaAges 18–70 - NCT07361822Recruiting
Opioid use after surgery: standard vs smart pump
This trial compares two ways to give pain medicine through an IV pump after surgery. It tests if a smart pump that adjusts the dose based on feedback works better than a standard pump that delivers a steady, fixed dose. This might help patients use less opioid pain medicine.
BeijingAges 18–65 - NCT07375121Recruiting
Comparing two pain pump settings for mixed surgeries
This study compares two ways of delivering pain medicine through an IV pump (called PCA) after surgery. One method gives a steady dose, and the other slowly reduces the dose. The goal is to see which works better and has fewer side effects.
BeijingAges 18–65 - NCT06978335Enrolling by invitation
Acupoint stimulation for better wound pain relief after surgery
This study tests if gentle stimulation of acupoints (like acupressure or a small device) can ease pain from a surgical wound. It is for adults who are having a surgery with a long incision and will be using a pain pump afterward.
Taipei, Peitou DistAges 18 years+ - NCT06054802Enrolling by invitation
Sleep and pain after spine surgery in teens
This study looks at how sleep quality before and after spine surgery affects pain recovery. It uses text messages to check in with participants, so a mobile device is needed.
Columbus, OhioAges 10–18 - NCT07017192Recruiting
Comparing anesthesia methods for hip replacement surgery
This study compares two types of anesthesia for people having a hip replacement through the front (anterior) approach. The goal is to see which method provides better pain control and recovery after surgery.
Torino, TOAges 18–85 - NCT07036393Recruiting
Acupuncture vs. TENS for pain after upper belly surgery
This trial compares two non-drug treatments — acupuncture and TENS — to see which works better for pain after upper abdominal surgery. You might join to help find a gentler option for recovery.
Al MansurahAges 20–45 - NCT06001502Recruiting
Virtual reality for pain and anxiety after heart bypass surgery
This trial tests whether using virtual reality (VR) goggles after heart bypass surgery can help reduce pain and anxiety. If you are having a planned CABG and have no major vision, hearing, or other health issues, you may be eligible.
Amsterdam, North HollandAges 18 years+ - NCT07344467Recruiting
Melatonin vs. Pregabalin for pain and anxiety after spine surgery
This trial compares two medications—melatonin and pregabalin—to see which works better at reducing pain and anxiety after spine surgery. It aims to find a safer, effective option for recovery.
Tanta, El-GharbiaAges 21–60 - NCT07550114Recruiting
Nerve blocks to reduce bleeding and pain after spine surgery
This study compares two types of nerve blocks (numbing injections) given during lumbar spine fusion surgery to see which better reduces bleeding and pain after the operation. If you're having spine surgery, this trial might help your recovery be smoother with less pain and bleeding.
Barcelona, BarcelonaAges 18 years+ - NCT06466941Recruiting
Understanding acute pain after surgery
This study surveys surgical patients about their pain and emotional experience to better understand acute pain. You may help by answering questions or sharing your story.
Boston, MassachusettsAges 18 years+ - NCT06808022Enrolling by invitation
Back exercises before spine surgery
This trial studies whether doing back exercises before spine surgery helps improve recovery. If you are having spine surgery and can safely do physical therapy, you may be able to join.
La Jolla, CaliforniaAges 18 years+ - NCT06973122Recruiting
Nerve blocks for pain after abdominal surgery
This study tests two different nerve-block methods to reduce pain inside the belly after surgery. It compares a block near the stomach nerves to a block in the abdominal wall, to see which works better for controlling deep pain.
AlexandriaAges 20–50 - NCT07288047Recruiting
Virtual reality for pain during early abortion
This study tests if using a virtual reality headset during a first trimester procedural abortion can help reduce pain and anxiety. You may be eligible if you are planning to have an abortion at Planned Parenthood of Western Pennsylvania and meet the criteria below.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT07352683Recruiting
Nerve block for kids having belly surgery
This trial tests a nerve block to reduce pain in children aged 1–15 who are having open abdominal surgery. It aims to see if this approach improves recovery.
UppsalaAges 1–15 - NCT06020677Recruiting
Latinx children and surgery study
This study looks at how Latinx families manage their child's pain after outpatient surgery. It aims to improve care for Spanish-speaking families.
Orange, CaliforniaAges 2–7
Hear when a new Pain After Surgery trial opens
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Common questions
- Are there clinical trials for pain after surgery?
- Yes. Clin2 currently lists 420 recruiting pain after surgery studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pain after surgery trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pain after surgery trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.