Clinical trials
Pain, Chronic Disease clinical trials
Below are recruiting pain, chronic disease clinical trials, each written for real people, not researchers. We’re tracking 457 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04512755Recruiting
AIMS medical outcomes study for new or established patients
This is an observational study where the AIMS team collects information from patients during a first visit or ongoing care. It helps the clinic understand patients’ experiences and outcomes, but it does not test a new medicine.
Seattle, WashingtonAges Any age - NCT04706195Recruiting
Person-centered online rehab for chronic pain on sick leave
This trial tests an early, personalized (person-centered) rehabilitation program delivered through eHealth to help people living with long-term non-cancer pain. It may help reduce pain impact and improve function while you are on sick leave from work.
GothenburgAges 18–65 - NCT06360965Recruiting
Acupoint patch for pelvic pain after PID
This trial tests a skin patch treatment (acupoint application) placed on specific points of the body to help relieve ongoing pelvic pain from pelvic inflammatory disease. It may be a good option if you have moderate pain and ultrasound findings of tubal thickening or fluid.
BeijingAges 18–50 - NCT06115083Recruiting
Pelvic floor training for men with chronic pelvic pain
This trial tests if pelvic floor muscle training can reduce chronic pelvic pain in men. It also looks at how well patient-reported symptoms match physical exam findings.
StockholmAges 18 years+ - NCT05752396Recruiting
Study of Pain Patterns Over Time in Kids
This study follows kids who have a specific type of chronic pain (headaches, stomach pain, or muscle/joint pain) to better understand how pain changes over time. It also checks whether certain factors are linked to those pain patterns.
Cincinnati, OhioAges 10–19 - NCT07761936RecruitingPhase 3
Safinamide for Parkinson's disease pain
This study tests whether safinamide, an add-on medication for Parkinson's disease, can reduce chronic pain in people who also experience motor fluctuations (times when symptoms return between doses). It aims to see if this treatment can improve pain and quality of life.
Verona, VenetoAges 18 years+ - NCT06413914Recruiting
CBT for long-term pain in rheumatic disease
This trial tests if cognitive behavioral therapy (a type of talk therapy that helps change pain-related thoughts and behaviors) can reduce long-term pain in people with rheumatic diseases. It also validates a new questionnaire (AE-FS) about how pain affects daily life.
OsloAges 18 years+ - NCT07711431Recruiting
Connection between gum disease and ongoing neck pain
This study looks at whether there is a link between gum (periodontal) disease and long-term neck pain without a clear cause. If you are between 30 and 55, have most of your own teeth, and don't take regular pain medicine, you may be able to help doctors understand this connection.
Niğde, Niğde ProvinceAges 30–55 - NCT05970783RecruitingPhase 3
Jincaopian tablets for ongoing pelvic pain after pelvic infection
This trial tests whether Jincaopian tablets can reduce long-lasting pelvic pain that happened after pelvic inflammatory disease. You may be able to join if your pain is still moderate to severe and other causes of pelvic pain have been ruled out.
Beijing, Beijing MunicipalityAges 18–50 - NCT07641504RecruitingPhase 2
Testing LY4065967 for chronic low back pain relief
This study tests whether a new medication called LY4065967 can reduce chronic low back pain. Researchers want to see if it works better than current treatments for people who have had lower back pain for at least 3 months.
Birmingham, AlabamaAges 18 years+ - NCT06070766Recruiting
At-home ketamine study for chronic conditions
This trial tests a ketamine protocol you can use at home. It may help if you have a long-term health condition.
Bigfork, MontanaAges 18 years+ - NCT06038409Recruiting
Ketamine therapy for chronic conditions
This trial tests if ketamine can help people with long-term health issues. It aims to find new treatments for chronic conditions that haven't responded well to other therapies.
Helena, MontanaAges 18 years+ - NCT07587047RecruitingPhase 1
Stem cell study for chronic lower back pain
This study tests a stem cell treatment for people with ongoing lower back pain. It aims to see if the therapy can help reduce pain and improve your quality of life.
Winter Park, FloridaAges 18–85 - NCT07525557Recruiting
Understanding Fear and Disability in Long-Term Neck Pain
This study explores how fear of movement, pain, and daily difficulties relate to each other in people with chronic neck pain lasting 3+ months. Understanding these connections may help improve future treatment approaches.
Samsun, SamsunAges 18 years+ - NCT07432425Recruiting
Exercise programs for chronic neck pain
This study compares different exercise programs to see which one improves physical and mental health in people with chronic neck pain. You may be eligible if you have had neck pain for at least 3 months and it is moderate to severe, but you haven't been in a recent neck pain rehab or exercise program.
Ankara, AltindagAges 20–65 - NCT07386548Recruiting
Biologic injection for low back disc problems
This study tests if an injection can help people with a herniated disc in the lower back who have not gotten better with other treatments and are already planning surgery. It aims to see if the injection can reduce symptoms and possibly avoid or improve surgery outcomes.
Manhattan, New YorkAges 18 years+ - NCT06731335RecruitingPhase 2
Psilocybin for chronic nerve pain that hasn't improved with other treatments
This study tests whether psilocybin (a compound found in certain mushrooms) can help reduce chronic nerve pain that has not responded well to standard medications. You will receive study treatment plus psychotherapy to see if it improves your pain.
Toronto, OntarioAges 18–65 - NCT07194239Recruiting
Lifestyle medicine for chronic pain in older adults
This trial tests if lifestyle changes like diet and exercise can reduce chronic muscle or joint pain in older adults. It focuses on people with long-lasting pain from conditions like arthritis.
Hong KongAges 60 years+ - NCT06932432Recruiting
Psychological support study for young adults with chronic pain
This study tests a new approach to psychological support for young adults (ages 18-25) with chronic pain that started in childhood. It uses daily surveys on your smartphone to adjust support based on what you need day to day.
Seattle, WashingtonAges 18–25 - NCT07137715Recruiting
Wellness and recovery for veterans with chronic back or neck pain
This study tests a psychological program to help veterans manage chronic back or neck pain. It aims to improve your wellbeing and daily function through counseling or coaching sessions.
Aurora, ColoradoAges 18 years+ - NCT07095036Recruiting
Spinal cord stimulation and sensation study
This study looks at how a spinal cord stimulator affects your sense of touch and movement. It may help doctors better understand how this device works for people with chronic pain.
Chapel Hill, North CarolinaAges 18–85 - NCT07011537Enrolling by invitation
Digital health program and TENS for chronic low back pain
This trial tests a digital health program combined with a TENS device (a small device that sends gentle electrical pulses to help with pain) for people with ongoing low back pain. It compares this approach to standard care, and you would be randomly assigned to one of the two groups.
Eden Prairie, MinnesotaAges 18 years+ - NCT07008105Recruiting
One session therapy for chronic pain
This study tests whether a single 90-minute online session can help people with chronic pain feel better. If you live with ongoing pain and want to try a brief psychological approach without medication, you may be a good fit.
Chicago, IllinoisAges 18 years+ - NCT06994559Recruiting
Music with ketamine for chronic pain
This study tests if listening to music during ketamine infusions helps reduce chronic pain better than ketamine alone. It is for people already getting ketamine infusions for non-cancer pain.
Montreal, QuebecAges 18 years+
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Common questions
- Are there clinical trials for pain, chronic disease?
- Yes. Clin2 currently lists 457 recruiting pain, chronic disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pain, chronic disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pain, chronic disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.