Clinical trials
Pain Control clinical trials
Below are recruiting pain control clinical trials, each written for real people, not researchers. We’re tracking 260 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06986122Recruiting
Testing virtual reality to help with pain
This study tests whether virtual reality can help change how you feel pain. You'll be asked to complete tasks and rate your experience.
Hanover, New HampshireAges 18–55 - NCT07278804Recruiting
Pain control options for IUD insertion
This study tests different pain control choices during IUD placement. It may help you find what works best for your comfort.
Durham, North CarolinaAges 18–50 - NCT06350786Recruiting
Using a placebo to help reduce opioid pain medication
This trial tests whether a special placebo pill, given with your knowledge, can help you reduce your opioid pain medication. You'll work with your own doctor to safely lower your dose while taking the placebo.
Zurich, Canton of ZurichAges 18 years+ - NCT06244732Recruiting
Pain control after open aneurysm surgery
This study tests two different ways to manage pain after open surgery for an abdominal aortic aneurysm. It compares a standard pain control method to another approach that may reduce the need for strong painkillers.
San Donato Milanese, MilanAges 18 years+ - NCT07360028Recruiting
Nerve blocks for pain after chest surgery
This trial tests two types of numbing injections (nerve blocks) to control pain after chest surgery done with a camera. It aims to find which block works better so you can recover more comfortably.
Cairo, Abbassia-EgyptAges 25–70 - NCT07120763RecruitingPhase 3
Better pain control for kids with broken wrists
This trial compares different ways to manage pain for children who come to the emergency room with a broken wrist that needs to be reset. The goal is to find which pain medicine or numbing method works best and is safest for kids.
Buffalo, New YorkAges 3–17 - NCT07190807Recruiting
Optimizing spinal cord stimulation for chronic back and leg pain
This trial tests if a spinal cord stimulator with a new way of adjusting electrical settings (called independent current control) can better manage chronic pain in the back, trunk, or limbs. The goal is to find more effective sequences to reduce pain and improve daily life.
Greenwood, ColoradoAges 18 years+ - NCT06716359Enrolling by invitation
Comparing two pain medicines after C-section
This trial compares two pain relievers, hydromorphone and nalbuphine, given through a patient-controlled pump after cesarean section. It aims to find which provides better pain control with fewer side effects.
Wuhan, HubeiAges 20–50 - NCT07677969Recruiting
Arm loss, balance, pain, and daily life study
This study looks at how the percentage of arm loss affects balance, neck and back pain, daily activities, and reaction time in people with one arm amputated who use a myoelectric or bionic hand. It may help understand how to improve care and rehabilitation.
AnkaraAges 18–65 - NCT05024344Recruiting
Nerve block to reduce pain after kidney stone surgery
This trial tests whether an “ESP block” (a targeted local anesthetic injection near nerves) works better than standard care to control pain after percutaneous kidney stone removal. If it helps with pain, it could reduce the need for stronger pain medicines after surgery.
Knoxville, TennesseeAges 18 years+ - NCT06869967Recruiting
Pain Control After Ear Surgery (Mastoidectomy)
This study tests a pain-blocking injection to reduce pain after a specific type of ear surgery (mastoidectomy). It may help you feel less pain after your operation.
IstanbulAges 18 years+ - NCT05906134RecruitingPhase 1/Phase 2
Pain control plan after minimally invasive esophagus surgery
This trial tests a pain-control method (using an epidural/nerve pain-block through the back, called neuraxial anesthesia) for people having minimally invasive esophagus removal surgery. It may help reduce pain after surgery and improve comfort during recovery.
Seattle, WashingtonAges 18 years+ - NCT04783454Recruiting
Preventing neck and back pain in teleworkers
This study tests ways to prevent neck and back pain in people who work at a computer from home or an office. If you qualify, you may be assigned to an intervention aimed at reducing pain and improving comfort.
Ghent, East FlandersAges 18–69 - NCT07721571Recruiting
Pain control after kidney stone surgery via tube site injection
This trial tests whether injecting a numbing medicine into the tube site after kidney stone removal can reduce pain. If you are having this surgery, this approach might help you feel more comfortable afterward.
Çorum, ÇorumAges 18–75 - NCT05131178Recruiting
Study for pain control after C-section
This trial looks at how to reduce pain after a C-section (cesarean delivery). You may be able to join if you’re having a scheduled or urgent C-section and can use the planned pain-control method.
Aurora, ColoradoAges 18–50 - NCT06728371RecruitingPhase 3
IV methadone for pain after heart surgery
This trial tests if methadone given through a vein can control pain better after heart surgery done through a breastbone incision. It may be an option for adults having planned heart surgery who are expected to wake up and breathe on their own within 12 hours.
Hong KongAges 18 years+ - NCT04260854Enrolling by invitationPhase 1
Bupivacaine for pain control during skin surgery
This Phase 1 study tests bupivacaine, a numbing medicine, to see how well it controls pain during cutaneous (skin) surgery. It’s primarily looking at safety and how the medicine works for people undergoing the procedure.
Chicago, IllinoisAges 19 years+ - NCT07272551Enrolling by invitation
Polyvagal therapy for chronic neck pain
This trial tests a new approach based on the polyvagal theory to help people with long-term neck pain. It uses gentle exercises and techniques to calm the nervous system and reduce pain.
Istanbul, MaltepeAges 18–50 - NCT06131658Recruiting
Functional training for iliotibial band syndrome in runners
This trial tests whether functional motor control exercises can reduce pain and improve flexibility and leg function in runners with IT band syndrome. It may help you run without pain on the outside of your knee.
Faisalābad, Punjab ProvinceAges 19–40 - NCT05193227RecruitingPhase 2
Slow-release lidocaine patch for pain after pelvic surgery
This Phase 2 study tests a slow-release form of lidocaine to reduce pain after surgery that uses a pelvic incision. If you’re having a qualifying pelvic operation, the study may help see whether this medication improves postoperative pain control.
Vancouver, British ColumbiaAges 19 years+ - NCT05511012Recruiting
Testing movement-control assessment in low back pain
This study checks whether a therapist’s judgment about how your back controls movement matches objective measurements (more technical testing). It may help improve how low back pain rehabilitation is assessed and planned.
Brest, FinistèreAges 18–99 - NCT06841276Recruiting
Digital tool for chronic pain relief study
This study tests a smartphone device called QoLibri that helps manage long-term pain. You use it at home for a few weeks to see if it reduces pain and improves daily life.
NaillouxAges 18 years+ - NCT03696199RecruitingPhase 4
Test better pain control after ankle fracture surgery
This trial studies a pain-control approach (a kind of nerve block) to see if it can reduce pain after surgery for certain ankle fractures. It may help you feel more comfortable while your ankle heals after an operation.
Burlington, MassachusettsAges 18–89 - NCT03707288Recruiting
Exercise study for neck and low back pain in medical students
This study looks at neck and low back pain in medical students and asks participants to follow a set exercise plan for a period of time. It may help researchers understand what kind of exercise support could improve symptoms in students.
Kingston, KingstonAges Any age
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Common questions
- Are there clinical trials for pain control?
- Yes. Clin2 currently lists 260 recruiting pain control studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pain control trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pain control trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.