Clinical trials
Pain Control clinical trials
Below are recruiting pain control clinical trials, each written for real people, not researchers. We’re tracking 261 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06350981Enrolling by invitationPhase 2/Phase 3
Pain control after lower back fusion surgery
This study is comparing different ways to manage pain after a specific type of lower back fusion surgery called TLIF. The goal is to find the best pain control plan to make recovery more comfortable.
Tampa, FloridaAges 18 years+ - NCT07711041Recruiting
Comparing three treatments for chronic neck pain
This trial compares three therapies—integrated neuromuscular inhibition, dry cupping, and dry needling—to see which works best for long-lasting mechanical neck pain. It may help if you have had neck pain for over six months with trigger points in your upper shoulder muscle.
GizaAges 18–40 - NCT06369922Recruiting
TENS for pain during urethral bulking for incontinence
This trial tests whether using a TENS device (a mild electrical stimulation machine) during an in-office urethral bulking procedure helps reduce pain. If you are a woman with stress urinary incontinence scheduled for this treatment, you may be able to join.
Rochester, New YorkAges 18 years+ - NCT07328256Recruiting
Comparing two muscle relaxation techniques for neck pain relief
This study looks at two different gentle stretching methods to see which works better for relieving neck pain. It might help if you have had neck pain for a while and it limits your movement.
Islamabad, Punjab ProvinceAges 19–44 - NCT07346755Recruiting
Nerve block and shoulder awareness in stroke-related pain
This study tests whether a nerve block (freezing a nerve near the shoulder) combined with joint position testing can reduce shoulder pain and improve movement in people who have had a stroke.
Istanbul, IstanbulAges 18–80 - NCT06894355Recruiting
Hydrotherapy for athletes with long-term back pain
This trial tests whether group hydrotherapy (water-based exercise) can help athletes with long-term low back pain. It may be a good fit if you are an active athlete, have had back pain for at least 3 months, and train frequently.
NetanyaAges 18 years+ - NCT06620133Recruiting
Pain education and goal setting for chronic low back pain
This trial tests whether learning about pain and setting your own exercise goals helps people with long-term low back pain become more active. You will receive online sessions and support to safely increase your physical activity.
Sydney, New South WalesAges 18 years+ - NCT06925152RecruitingPhase 4
Nerve block for C-section pain in complex surgery history
This study tests a targeted numbing injection (a nerve block) in the belly wall during C-sections to improve pain control and recovery for people who have had multiple or complex abdominal surgeries. It aims to see if this approach reduces the need for strong pain medicines.
Memphis, TennesseeAges 18–50 - NCT03695887RecruitingEarly Phase 1
Disposable nitrous oxide for pain during burn dressing changes
This early-stage study tests whether using disposable nitrous oxide canisters can better control pain when you need burn dressing changes. It may help by making dressing changes more comfortable, but eligibility depends on your burn size, health, and breathing ability.
Winnipeg, ManitobaAges 18 years+ - NCT04134702Recruiting
Acupuncture for less pain after outpatient knee surgery
This study tests whether acupuncture can reduce pain after outpatient arthroscopic knee surgery done under general anesthesia. It may help by improving pain control while avoiding certain medicine side effects, but you must meet several specific safety and medication limits.
Greifswald, VorpommernAges 19–55 - NCT06548646Recruiting
Nerve blocks for pain relief after mastectomy
This study compares two types of nerve blocks (thoracic interfascial plane block vs. erector spinae plane block) to see which provides better pain relief after a mastectomy. It may help you have less pain and need fewer painkillers after surgery.
Cairo, AbbasiyaAges 21 years+ - NCT06570577Recruiting
Nerve block for pain after cervical spine surgery
This trial tests whether a nerve block can reduce the need for opioid pain medication after back-of-neck spine surgery. It may help patients have better pain control with fewer side effects.
Stony Brook, New YorkAges 18–75 - NCT07158476RecruitingPhase 4
Steroid injection for pain after ACL repair
This trial tests whether a single dose of methylprednisolone (a steroid) can reduce pain after ACL knee surgery. You will be randomly assigned to receive either the steroid or a placebo, and your pain levels will be tracked.
St Louis, MissouriAges 13–50 - NCT07211386Recruiting
Nerve block for severe cancer-related abdominal pain
This study tests whether a nerve block, called an erector spinae plane block, can reduce severe abdominal pain in people with gastrointestinal cancer who come to the emergency room. If you have cancer in your digestive system and are in pain that isn't controlled, this trial may help.
Philadelphia, PennsylvaniaAges 18 years+ - NCT07315308Recruiting
Nerve block before heart surgery and painkiller use
This study tests whether a numbing injection in the chest before heart surgery can reduce the amount of pain medicine needed during the operation. It may help you manage pain better and recover more comfortably.
Gaziantep, SahinbeyAges 18–65 - NCT07683273Enrolling by invitation
Breathing exercises for neck and upper back pain
This study tests whether diaphragmatic breathing exercises can help reduce chronic, non-specific neck and upper back pain. If you have this type of pain that is not caused by an injury or disease, you may be able to join.
Trabzon, OrtahisarAges 18–60 - NCT06466330Recruiting
Knee embolization for post-replacement pain
This trial tests a non-surgical treatment called microparticle geniculate artery embolization for people with persistent knee pain after a total knee replacement. It aims to reduce pain by blocking tiny blood vessels that may be causing inflammation.
CréteilAges 40–80 - NCT06569953RecruitingPhase 4
Numbing Medicine for Pain After Lung Surgery
This study tests whether a long-lasting numbing medicine (liposomal bupivacaine) injected near the spine can better control pain after lung surgery. It compares this to a standard numbing medicine, and aims to help patients recover with less pain after surgery.
Chongqing, Chongqing MunicipalityAges 18 years+ - NCT06395428RecruitingPhase 4
Haloperidol for severe back pain in the ER
This study tests whether the medication haloperidol, given in the emergency room, can help relieve severe back pain that started on its own (not from an injury). It compares haloperidol to a common pain reliever called ketorolac.
Kalamazoo, MichiganAges 18–65 - NCT06373978RecruitingPhase 4
Non-narcotic pain relief after elbow needle procedure
This study tests non-narcotic pain medicine after a needle procedure for chronic elbow tendon pain. It compares different pain-relief options to find what works best without opioids.
Coral Springs, FloridaAges 18–65 - NCT05953155Recruiting
Yoga for chronic back pain with a poorer outlook
This trial studies whether a yoga program can reduce symptoms and improve function for people with long-lasting, non-specific back pain and a poorer prognosis. You may be eligible if your back pain has lasted at least 3 months and you meet certain pain and questionnaire scores.
Belo Horizonte, Minas GeraisAges 18–60 - NCT04704297RecruitingPhase 4
Trigger point shots for low back muscle pain
This trial tests whether injecting sore “trigger points” in low back muscles helps improve chronic low back pain. It compares treatments in people with specific low back muscle pain patterns and excludes several other causes of pain.
Tacoma, WashingtonAges 18 years+ - NCT04102566RecruitingPhase 4
Better pain control during TURP surgery
This trial tests whether a pain-control approach can make TURP (prostate surgery through the urine tube) more comfortable. It may help you manage pain with the study medicines during and after your procedure.
Seattle, WashingtonAges 18 years+ - NCT07607262Recruiting
Comparing two injection methods for pain relief after gallbladder surgery
This trial tests two ways of giving pain medicine during gallbladder removal surgery. One method uses standard local anesthetic injection, the other uses a special injection technique that may provide better pain relief.
Sancaktepe, IstanbulAges 18–75
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Common questions
- Are there clinical trials for pain control?
- Yes. Clin2 currently lists 261 recruiting pain control studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pain control trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pain control trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.