Clinical trials
Pain Control clinical trials
Below are recruiting pain control clinical trials, each written for real people, not researchers. We’re tracking 253 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07731347RecruitingPhase 1
Fun techniques for kids during blood draws
This study compares two techniques to make blood draws less scary for children ages 5-7. It looks at which method helps kids stay calmer and feel less pain.
Iğdır, IğdırAges 5–7 - NCT07242170Recruiting
Comparing nerve blocks for pain after knee replacement surgery
This trial tests if adding extra nerve blocks (sciatic, BiFeS, or IPACK) to the usual adductor canal block can reduce pain after total knee replacement. The goal is to find a better way to manage pain and improve recovery.
Erzincan, MerkezAges 18–75 - NCT06962475Recruiting
Custom foot orthotics for chronic forefoot pain
This trial tests if custom foot orthotics (shoe inserts) can reduce chronic pain under the ball of the foot. If you have had forefoot pain for at least 3 months and can walk without a cane or walker, you may be able to join.
Trois-Rivières, QuebecAges 18 years+ - NCT05773482Recruiting
Breathing and attention training for fibromyalgia pain
This study tests whether breathing and attention exercises can change how your body controls pain in people with fibromyalgia. It may help you learn non-medication ways to influence pain signals and improve comfort.
Gainesville, FloridaAges 18–70 - NCT05421416RecruitingPhase 2
Loratadine to prevent bone pain after stem cell transplant treatment
This trial tests loratadine (an allergy medicine) to see if it can prevent bone pain caused by a growth-factor injection used during lymphoma or multiple myeloma treatment. It may help reduce pain around the time you get that injection and your upcoming stem cell transplant.
Edmonton, AlbertaAges 18 years+ - NCT06663956RecruitingPhase 3
Web app for cancer pain management study
This trial tests whether a special website or app can help people with cancer do a better job managing their pain. If you have moderate or severe cancer pain that needs morphine and you can use a simple app to track your symptoms, this may help you feel better.
Chengdu, SichuanAges Any age - NCT06413277Recruiting
ECAP-controlled spinal cord stimulation for chronic pelvic pain
This trial tests a new type of spinal cord stimulator that uses closed-loop technology to treat chronic pelvic pain caused by a known injury. It may be an option if your pain is severe and hasn't responded to other treatments.
New York, New YorkAges 18 years+ - NCT07864896RecruitingPhase 3
Study of a new pain medicine after knee replacement surgery
This trial tests a new oral pain medicine called suzetrigine for people who have a knee replacement. It aims to see if it helps control pain after surgery better or with fewer side effects than usual care.
New York, New YorkAges 18–80 - NCT07226700RecruitingPhase 3
Suzetrigine for pain after hip replacement surgery
This study tests an investigational pain medicine called suzetrigine to see how well it controls pain after total hip replacement surgery. It is for adults 18–80 who are having a first-time hip replacement and can receive spinal anesthesia.
New York, New YorkAges 18–80 - NCT07002944Recruiting
Testing nerve treatment for shoulder pain after mastectomy
This study compares two types of pulsed radiofrequency (a minimally invasive treatment using radio waves) to see which better relieves shoulder pain in women who have had a mastectomy. It's for women who still have pain despite taking a high dose of tramadol.
CairoAges 18–65 - NCT07473206Recruiting
Laughing gas for pain during office hysteroscopy
This study tests whether using laughing gas (nitrous oxide) plus a calming video on a screen can reduce pain and anxiety during a quick procedure to look inside the uterus (hysteroscopy). If you are having this procedure, the trial may help you feel more comfortable.
BiellaAges 25–60 - NCT07297901Enrolling by invitation
Breathing app study for migraine relief
This trial tests a smartphone-based breathing program to help reduce migraines. It uses heart rate data to guide breathing exercises tailored to you.
Phoenix, ArizonaAges 18 years+ - NCT07037888RecruitingPhase 4
Ketorolac for pain after hip arthroscopy
This study tests whether ketorolac, a nonsteroidal anti-inflammatory drug (NSAID), helps manage pain after hip surgery. It may offer an opioid-sparing option for patients with femoroacetabular impingement (FAI).
Detroit, MichiganAges 18–89 - NCT04242589RecruitingPhase 2
Radiation plus bone cement for painful spinal metastasis pain
This trial tests adding a bone-cement procedure (vertebroplasty) along with radiation to reduce pain from cancer that has spread to the spine. It is for adults with painful metastatic (spread) tumors in the middle or lower spine, without current spinal cord pressure.
Edmonton, AlbertaAges 18 years+ - NCT06859710RecruitingPhase 1
THC and CBD as a harm reduction strategy
This study looks at whether different types of cannabis (containing THC and/or CBD) might help people who use cannabis regularly reduce potential harms. You will be asked to take cannabis in a controlled setting and complete tasks and questionnaires.
Los Angeles, CaliforniaAges 21–55 - NCT06659991RecruitingEarly Phase 1
Pain and daily tasks in jaw joint disorder
This study tests how pain from a jaw joint disorder (TMD) affects your ability to do daily tasks. You'll track your pain and activities on your smartphone to help researchers understand the link.
Minneapolis, MinnesotaAges 21–65 - NCT05730491Recruiting
Online parenting program for kids with IBS-related belly pain
This trial tests an online social learning program to help parents support their child when the parent has irritable bowel syndrome (IBS) or related belly pain. It may help families build coping skills and resilience through guided parent sessions.
Seattle, WashingtonAges 18 years+ - NCT07241949Recruiting
Nerve block for gallbladder surgery pain relief
This study tests a nerve block called the external oblique intercostal block to reduce pain after laparoscopic gallbladder removal. If you are having this surgery, the block may help you need less pain medication and feel more comfortable after the procedure.
AdanaAges 18–65 - NCT07830446Recruiting
Pain relief injections for breast surgery
This trial tests whether a special numbing injection (called a fascial plane block) given before breast surgery can reduce pain after the operation. It compares this to standard pain management to see if it helps you recover with less discomfort.
BursaAges 18–80 - NCT07729930Recruiting
Creatine supplement study for healthy middle-aged women
This study is testing a creatine supplement (a substance that may help with energy and muscle function) in healthy middle-aged women. You may join if you are between 35 and 65, a non-smoker, and have a certain activity level.
LoughboroughAges 35–65 - NCT07035314Recruiting
Comparing medicines for pain after tonsil removal in children
This study compares two ways to manage pain after tonsil removal in children: a medication given by mouth or injection versus a medication applied directly to the surgical site. The goal is to find which approach works better for pain control.
CairoAges 4–10 - NCT06936800Enrolling by invitation
Pinaverium Bromide to Prevent Pain After Shock Wave Treatment
This trial tests if a drug called pinaverium bromide can help prevent pancreatitis and reduce pain after a procedure that uses shock waves to break up large gallstones in the pancreas. It may be an option for people with chronic pancreatitis and stones that are at least 5 mm wide.
Jinan, Wenhuaxi RoadAges 18–85 - NCT07605013Recruiting
Neck Exercises for Office Workers: Building Strength and Function
This study tests whether specific neck mobilization techniques (gentle movements and stretches) can improve neck strength and function in desk workers. You would be a healthy control participant to help researchers understand how these techniques work in people without existing neck pain.
IstanbulAges 18–40 - NCT06905340Recruiting
Pain-guided opioid use during surgery with regional anesthesia
This trial uses a special monitor (NOL index) to help doctors give just the right amount of pain medicine during surgery. It is for people having trauma or orthopedic surgery who are also getting regional anesthesia.
HamburgAges 18 years+
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Common questions
- Are there clinical trials for pain control?
- Yes. Clin2 currently lists 253 recruiting pain control studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pain control trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pain control trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.