Clinical trials
Pain Management clinical trials
Below are recruiting pain management clinical trials, each written for real people, not researchers. We’re tracking 349 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04730700Recruiting
Radiofrequency treatment test for facet back pain
This study compares a nerve procedure (radiofrequency “neurotomy” using an expandable electrode) to non-procedure medical care for long-lasting low back pain from facet joints. It aims to see whether the procedure helps more safely than conservative treatment.
Kansas City, KansasAges 18 years+ - NCT05767619Recruiting
Digital tool to guide care for chest pain calls
This trial tests a digital decision-support tool that helps emergency teams manage people who call for help because of chest pain. It may improve how safely and consistently chest pain is assessed and treated in the ambulance setting.
Kungsbacka, Region HallandAges 18 years+ - NCT06774274RecruitingPhase 4
Ketamine for pain after major orthopedic surgery: drip vs. pump
This study tests two ways of giving a medicine called ketamine to control pain after major bone or joint surgery. One method is a steady infusion (drip) through a vein, and the other is a patient-controlled pump (PCA) that lets you press a button for more medicine when you need it.
Medellín, AntioquiaAges 18 years+ - NCT07523802Recruiting
Managing pain after gum graft surgery with two methods
This trial tests two different ways to protect and manage pain in the mouth after a gum graft surgery. You would compare a product called Ora-Aid with a custom acrylic stent (a protective cover) to see which helps with healing and reduces discomfort better.
CairoAges 18 years+ - NCT07600892Enrolling by invitation
Pain-at-Work Toolkit for managing chronic pain at work
This study tests a toolkit designed to help working adults manage chronic pain while on the job. The toolkit aims to make work more manageable and enjoyable for people living with ongoing pain.
Nottingham, NottinghamshireAges 18 years+ - NCT05974384Recruiting
Music during closed treatment to ease wrist fracture pain
This study looks at whether playing music while doctors perform a closed procedure to realign a broken wrist can reduce pain and anxiety. It may help by making the procedure feel calmer for some people.
Sabadell, BarcelonaAges 18–100 - NCT06509087Recruiting
Combining CT and MRI for joint pain procedure
This study tests a procedure called transarterial microembolization for chronic shoulder or knee pain that hasn't improved with other treatments. It uses both CT and MRI to guide the procedure and see if it can help reduce pain.
TaipeiAges 20–80 - NCT06265636Recruiting
Nerve stimulation for jaw pain and function in TMD
This trial tests whether gentle electrical stimulation of a nerve in your jaw can reduce pain and improve chewing, talking, and mouth opening for people with temporomandibular joint disorder (TMD).
Alcorcón, MadridAges 18–65 - NCT07683468Recruiting
A self-help kit for pain during sex with endometriosis
This trial tests if a special kit you can use at home helps reduce sexual pain caused by endometriosis. It might offer a new way to manage this common symptom.
StainsAges 18–45 - NCT07500012Recruiting
Ear nerve stimulation for breast cancer pain
This study tests whether gentle electrical stimulation of a nerve in your ear (called taVNS) can help reduce pain and improve symptoms for breast cancer survivors. You would need to have finished your main treatments, have ongoing pain, and be willing to provide stool samples and undergo brain scans.
Tallahassee, FloridaAges 18–79 - NCT05794373Enrolling by invitation
Training physiotherapists for disabling low back pain
This observational study looks at how well municipality-based physiotherapists manage disabling low back pain after specific training. It focuses on people with significant low back pain symptoms to see what care works best in real-world settings.
MiddelfartAges 18–65 - NCT06728579RecruitingPhase 2
Group therapy for joint pain in breast cancer survivors
This study tests two supportive group programs—one using mindfulness skills, the other providing supportive talk therapy—to help breast cancer survivors manage joint pain caused by hormone-blocking pills. If you have ongoing joint pain and are taking an aromatase inhibitor, you may be able to join a free, video-based group.
San Diego, CaliforniaAges 18 years+ - NCT04691037Recruiting
CT heart scan to guide care for stable chest pain
This trial studies whether a CT heart scan (CCTA) can better guide treatment decisions for people with stable chest pain caused by blocked heart arteries. It may help your care team choose the next best step based on scan results.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07063147Recruiting
Heart ultrasound for stable chest pain management
This study uses a heart ultrasound (TTE) to help doctors better manage stable chest pain. If you have chest pain that may be from a blocked artery but haven't had a heart attack or heart procedures before, this trial could help improve your care.
TianjinAges 18 years+ - NCT06308029Recruiting
E-health pain self-management for breast cancer survivors
This trial tests an online program to help people manage lasting pain after breast cancer treatment. It's designed for those whose pain still gets in the way of daily life, even after finishing primary treatment.
AntwerpAges 18 years+ - NCT06999772Recruiting
Combining brain stimulation with physiotherapy for chronic back pain
This study tests if adding a non-invasive brain stimulation technique to physiotherapy can help veterans with chronic low back pain. It aims to improve pain and function by targeting both the brain and the body.
Québec, QuebecAges 18–65 - NCT07344090Recruiting
Using a decision tool to manage fever and pain in children
This trial tests a decision-making system to help parents manage fever and acute pain in young children. It's for children aged 3 months to 5 years who need paracetamol for fever or pain.
Florence, ItalyAges 3 months–5 years - NCT07717151Recruiting
Preventing long-term pain after surgery for chronic opioid users
This trial tests a method to prevent chronic pain after surgery in people who already take opioids regularly. It may help reduce long-term pain and improve recovery.
AmiensAges 18 years+ - NCT07310953Recruiting
Using new pain scales to guide rescue pain medicine after surgery
This trial tests if a simple pain scale (the NVS and PFAS) can help doctors better decide when to give extra pain medicine after surgery. It may help control pain more quickly and effectively after a procedure called VATS.
VigoAges 18 years+ - NCT07309731Recruiting
Hot vs. cold radiofrequency for chronic low back pain from facet joints
This trial compares two types of radiofrequency treatment (cooled vs. thermal) to see which works better for chronic pain coming from the small joints in your lower back. It is for people who have had back pain for at least 3 months and haven't gotten enough relief from usual treatments like pain medicine or physical therapy.
Zagazig, ElsharqyaAges 30–70 - NCT06149819Recruiting
Chest pain nurse track for emergency care
This trial is testing a nurse-led care pathway for people who come to the emergency room with chest pain that is not caused by an injury. The goal is to see if this approach can improve care and speed up the process.
Grenoble, GrenobleAges 18 years+ - NCT05217160RecruitingPhase 4
KeraStat gel with morphine for non-healing painful open wounds
This study tests whether KeraStat® gel that delivers morphine through the skin can reduce pain and help manage non-healing ulcers or open wounds. You may be eligible if your wound fits specific size and depth limits and you can track pain every day.
San Antonio, TexasAges 18 years+ - NCT06845215Recruiting
Pain block comparison for abdominoplasty recovery
This trial compares two types of nerve blocks (TAP and ESP) to see which provides better pain relief after tummy tuck surgery. Both are injections near the abdominal muscles that numb the area, and you'll also have a patient-controlled pain pump.
Ankara, KeçiörenAges Any age - NCT07485803RecruitingPhase 4
Methadone for pain after knee replacement
This study tests whether methadone, a type of pain medicine, helps control pain better after knee replacement surgery. It is for people who have not used narcotics recently and are otherwise healthy.
Denver, ColoradoAges 21–75
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Common questions
- Are there clinical trials for pain management?
- Yes. Clin2 currently lists 349 recruiting pain management studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pain management trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pain management trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.