Clinical trials
Pain Management clinical trials
Below are recruiting pain management clinical trials, each written for real people, not researchers. We’re tracking 349 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06761989Recruiting
Comparing two ways to control pain after Whipple surgery
This study compares two ways to manage pain after a Whipple procedure: one is a shot of morphine into the fluid around the spine, and the other is a small tube placed under the skin at the surgical cut that delivers pain medicine continuously. The goal is to see which method provides better pain relief and recovery.
Seoul, SeoulAges 19 years+ - NCT07226700RecruitingPhase 3
Suzetrigine for pain after hip replacement surgery
This study tests an investigational pain medicine called suzetrigine to see how well it controls pain after total hip replacement surgery. It is for adults 18–80 who are having a first-time hip replacement and can receive spinal anesthesia.
New York, New YorkAges 18–80 - NCT06856733Recruiting
Better opioid management for long-term non-cancer pain
This study tests a new way to help people who have been taking opioids for chronic pain (not caused by cancer) for at least 90 days. The goal is to improve treatment and reduce risks, such as developing tolerance or side effects, while still managing pain effectively.
Strängnäs, SörmlandAges 18–70 - NCT07380789Recruiting
Managing acute chest pain after battle injuries
This study is testing better ways to manage severe chest pain after combat injuries in Ukraine. If you have chest pain from battle and are 18 or older, it may help find a treatment that works for you.
RivneAges 18–60 - NCT06038240Recruiting
Pain self-management program for knee replacement
This study is testing a program to help people manage pain on their own before and after total knee replacement surgery. It aims to improve recovery and reduce reliance on pain medications.
Charlottesville, VirginiaAges 18–85 - NCT07502742Recruiting
Pain in aging athletes and nonathletes
This study looks at how pain affects older adults who are either current master's athletes, former competitive athletes, or nonathletes. It aims to understand why some people have more pain and what helps them stay active.
Milwaukee, WisconsinAges 35–65 - NCT07761936RecruitingPhase 3
Safinamide for Parkinson's disease pain
This study tests whether safinamide, an add-on medication for Parkinson's disease, can reduce chronic pain in people who also experience motor fluctuations (times when symptoms return between doses). It aims to see if this treatment can improve pain and quality of life.
Verona, VenetoAges 18 years+ - NCT07141108Recruiting
Using a digital tool to track chronic pain and improve quality of life
This trial tests a digital tool that helps you track your pain and activity level. The goal is to see if using the tool can improve your quality of life. You would use a smartphone or tablet app and share updates with your primary care team.
Malmö, Skåne CountyAges 18 years+ - NCT07694141Recruiting
Pain Relief After Chest Surgery
This trial studies how well different pain medications work after thoracic (chest) surgery. It aims to find the best way to manage pain and improve recovery.
Las Palmas de Gran Canaria, Las PalmasAges 18 years+ - NCT06663956RecruitingPhase 3
Web app for cancer pain management study
This trial tests whether a special website or app can help people with cancer do a better job managing their pain. If you have moderate or severe cancer pain that needs morphine and you can use a simple app to track your symptoms, this may help you feel better.
Chengdu, SichuanAges Any age - NCT06937853Recruiting
Genes and painkiller response for tooth pain
This trial tests whether your genes affect how well a common painkiller (NSAID) works for tooth pain after a root canal procedure. It may help find the best pain relief for you.
Erzurum, ErzurumAges 18–65 - NCT07454993Recruiting
Music during colonoscopy study
This trial tests whether listening to music during a colonoscopy can make the procedure more comfortable. If you are having a routine colonoscopy without deep sedation, you may be able to join.
Esbjerg, Region SydAges 18 years+ - NCT07496203Recruiting
BETY program after knee injections for osteoarthritis
This trial tests if a special exercise and education program called BETY helps people with knee osteoarthritis feel better after getting a knee injection. You may qualify if you had a knee injection in the last month and have moderate knee arthritis.
Ankara, SamanpazarıAges 18 years+ - NCT07157709Enrolling by invitation
Pain management toolkit for nursing home residents
This trial tests a toolkit designed to help manage pain. It is for people living in a nursing home who have pain.
Graz, StyriaAges 18 years+ - NCT05231460Enrolling by invitationPhase 4
Pain plan study for people before bariatric surgery
This study tests a specific pain-management plan for people who are scheduled for sleeve gastrectomy (done by laparoscopy or robotics). The goal is to find how to control pain safely around the time of surgery while avoiding certain risks and medication issues.
Phoenix, ArizonaAges 18 years+ - NCT07308730Recruiting
Pain diary after gallbladder surgery
This study looks at whether using a pain diary can help people manage pain better after gallbladder removal surgery. If you are having this surgery for the first time and can read and write in Turkish, you may be able to join.
Muğla, MenteşeAges 18 years+ - NCT06984354Recruiting
Digital treatments for chronic low back pain
This trial tests a smartphone app to help people with long-term low back pain. It aims to see if digital treatments can reduce pain and improve daily function.
Randwick, New South WalesAges 18 years+ - NCT06153199Recruiting
Managing low back pain in nursery and landscape workers
This study tests a self-management program to help people who work in nurseries or landscaping manage their low back pain. It aims to give you practical tools to reduce pain and stay active at work.
Gainesville, FloridaAges 18 years+ - NCT07073846RecruitingPhase 4
Lidocaine and dexmedetomidine for pain after weight-loss surgery
This study tests whether adding two medicines (lidocaine and dexmedetomidine) to your anesthesia during weight-loss surgery can reduce pain, swelling, and stress on the body. It might help you have a smoother recovery.
Mexico City, Mexico CityAges 18–60 - NCT02352116Recruiting
Pain treatment plan after outpatient surgery for young children
This study tests a pain-management plan right after surgery for children ages 1–6 who go home the same day. It aims to see whether the plan improves comfort after anesthesia without requiring longer hospital recovery.
New York, New YorkAges 1–6 - NCT07630350Enrolling by invitation
Virtual Reality for Young People With Chronic Pain
This study tests whether wearing virtual reality goggles can help young people (ages 7–21) manage chronic pain in their neck, shoulders, or arms. Researchers want to see if VR activities can reduce pain and improve daily life.
Allison Park, PennsylvaniaAges 7–21 - NCT06566664Enrolling by invitation
Nerve stimulation to help with arm surgery nerve blocks
This study tests if using a small electrical stimulator on the skin can make a nerve block work better for arm surgery. If you are having planned arm surgery and getting a nerve block, you may be able to join.
Stanford, CaliforniaAges 18 years+ - NCT03737292RecruitingPhase 4
Numbing medicine for chest surgery pain after small lung operations
This trial tests whether a long-lasting numbing shot (liposomal bupivacaine) works better than a regular numbing shot (plain bupivacaine) for pain after minimally invasive chest surgery. It may help you have less post-surgery pain and potentially use less pain medication.
Hershey, PennsylvaniaAges 18 years+ - NCT07195422Recruiting
Study of a new device for low back pain relief
This trial tests a wearable device called Japet.W+ to see if it can help reduce chronic low back pain. It might be an option for people who have had lower back pain for a long time and are looking for non-surgical relief.
Clermont-FerrandAges 18–80
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Common questions
- Are there clinical trials for pain management?
- Yes. Clin2 currently lists 349 recruiting pain management studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pain management trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pain management trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.