Clinical trials · Houston, TX
Pain clinical trials in Houston
We’re tracking 59 recruiting pain studies with a site in or near Houston — including Phase 1, Phase 1/Phase 2, Phase 2 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies near Houston
- NCT06065449RecruitingPhase 3
Comparing two radiation therapies for painful bone metastases
This trial compares two types of radiation therapy to relieve pain from cancer that has spread to the bones. It aims to see whether a more targeted, high-dose approach (SBRT) works better than standard palliative radiation.
Houston, TexasAges 18 years+ - NCT06069154Enrolling by invitation
Freezing nerves for rib fracture pain
This study tests a procedure called cryoneurolysis, which uses cold to temporarily freeze nerves near broken ribs to relieve pain. It is for adults who have 1 to 6 recently broken ribs with at least moderate pain and are already getting a nerve block injection.
Houston, TexasAges 18 years+ - NCT03427736Recruiting
Anesthetics and pain medicines study for children
This study looks at how children process certain anesthetics and pain medicines. It aims to find the best doses for safety and effectiveness.
Houston, TexasAges 6 months–17 years - NCT07507422Recruiting
Post-market study of Inceptiv spinal cord stimulation
This study follows people receiving Inceptiv, a spinal cord stimulator from Medtronic, to see how well it works over time. It is for adults with chronic back or limb pain who have not tried spinal cord stimulation before.
Houston, TexasAges 18 years+ - NCT07116109Recruiting
Brain Stimulation Plus Therapy for Pain and PTSD
This study tests whether a brain-stimulation headband (called tDCS) combined with a proven talk therapy for PTSD can help reduce both chronic pain and PTSD symptoms. It is for adults who have had chronic pain for at least 6 months and also have PTSD.
Houston, TexasAges 21 years+ - NCT07568015Recruiting
Nerve-targeted treatment for lateral hip pain
This study tests an experimental treatment that targets nerves around the hip to relieve pain on the outside of the hip. It may help people who have tried other treatments without enough relief.
Houston, TexasAges 22–80 - NCT03511846Enrolling by invitationPhase 1
Pain biomarker study for headache or back nerve pain
This study looks at measurable “pain signals” (biomarkers) in people with certain headache disorders or lumbar nerve pain, and compares them with healthy people. It may help researchers better understand what drives pain and how it can be detected.
Houston, TexasAges 18 years+ - NCT06884865RecruitingPhase 2
Study of an experimental knee injection for osteoarthritis pain
This study tests a new investigational medicine injected into the knee to see if it is safe and tolerable for people with painful knee osteoarthritis. It may help reduce pain and improve knee function.
Houston, TexasAges 45–80 - NCT06004882Recruiting
Nerve stimulation vs. steroid injection for chronic knee pain
This study compares two treatments for long-term knee pain: a nerve stimulation device placed near the knee versus a steroid shot into the joint. The goal is to see which works better for pain relief.
Houston, TexasAges 18 years+ - NCT05991453Recruiting
Recovery after IV vs. inhaled anesthesia for non-cardiac surgery
This trial compares recovery after two types of general anesthesia: one given through an IV (propofol) and one inhaled as a gas. It aims to see which approach leads to a smoother recovery for people having non-cardiac surgery.
Houston, TexasAges 18 years+ - NCT04278404Recruiting
Drug safety study for children already on certain medicines
This study measures how certain medicines move through the body and checks their safety in children. It may help doctors better understand dosing and side effects in kids who are already receiving these treatments, or in some kids who recently tested positive for COVID-19.
Houston, TexasAges birth–20 years - NCT03877653Recruiting
Freedom-1 treatment for long-term knee pain in adults
This study tests a procedure called Freedom-1 to reduce long-term, limiting knee pain from knee arthritis. It may help if other non-surgical options didn’t work and you meet specific knee and health requirements.
Houston, TexasAges 18 years+ - NCT04693377Recruiting
Freezing tumor treatment plus targeted radiation for painful bone spread
This study tests whether combining a “freezing” procedure (cryoablation) with focused external radiation (SBRT) can reduce pain from bone metastases. It’s for people with certain cancers that have spread to bone and are having significant pain in a specific bone spot.
Houston, TexasAges 18 years+ - NCT07405645Recruiting
Focused Ultrasound for Cancer Pain in the Head or Neck
This trial tests a non-invasive focused ultrasound treatment aimed at a specific brain area to reduce severe cancer-related pain in the head, neck, or upper chest. It may help if your pain hasn't responded to standard medications.
Houston, TexasAges 18–85 - NCT06381791RecruitingPhase 1/Phase 2
CBD for pain after shoulder surgery
This study tests if CBD (a cannabis extract) can help manage pain after rotator cuff repair surgery. It aims to find a better way to control pain and reduce the need for stronger painkillers.
Houston, TexasAges 18 years+ - NCT06271265RecruitingPhase 1
Testing EXPAREL for pain after heart surgery in children
This study tests a long-acting pain medicine (EXPAREL) given during heart surgery to see how it works in young children. The goal is to help control pain after surgery with fewer side effects.
Houston, TexasAges birth–6 years - NCT05110989Recruiting
Registry study of pain relief after freezing intercostal nerves
This study collects real-world information about how well freezing (cryoablation) of the intercostal nerves helps with pain after a procedure. It may help doctors understand outcomes and improve care for future patients.
Houston, TexasAges 12 years+ - NCT06162403Recruiting
Nerve stimulation for chemo-related leg pain
This study tests whether a small device that sends gentle electrical pulses to nerves in your leg can relieve pain caused by chemotherapy. If you have ongoing nerve pain in your legs from past chemo, this treatment might offer a new way to manage it.
Houston, TexasAges 18–85 - NCT01550575Recruiting
Study of outcomes in people treated with Boston Scientific devices
This study looks back at what happened to patients after treatment (or if they could have used) Boston Scientific medical devices. It may help improve how these devices are used and understand real-world results.
Houston, TexasAges 18 years+ - NCT07579182RecruitingPhase 1
How Exercise and Hormones Affect Pain in Women
This study looks at how exercise affects pain and hormone levels in women. Researchers will ask you about your activity level, do some physical tests, and measure how your body responds to exercise over several visits.
Houston, TexasAges 18–60 - NCT07353931RecruitingPhase 3
Study of eloralintide for knee osteoarthritis pain in people with overweight or obesity
This trial tests an investigational drug called eloralintide to see if it can reduce knee pain in people with osteoarthritis who also have overweight or obesity. You may be able to join if you have knee osteoarthritis, a BMI of 27 or higher, and have tried to lose weight with diet before.
Houston, TexasAges 18 years+ - NCT06840262Recruiting
Nerve surgery for pain after cancer amputation
This study tests two surgical techniques—target muscle re-innervation and regenerative peripheral nerve interfaces—alone or together, to help reduce pain felt in the remaining limb or the missing limb (phantom pain) after amputation for cancer. The goal is to find the best way to manage pain and improve quality of life.
Houston, TexasAges 18 years+ - NCT06968689Recruiting
Brain activity study for experimental and chronic pain
This study uses MRI and EEG to look at brain connections involved in pain. It may help us understand how the brain processes pain and could lead to better treatments.
Houston, TexasAges 18–60 - NCT06354699Recruiting
Pain after surgery in children: a long-term study
This study looks at children who have certain types of surgery to understand who might have ongoing pain, what causes it, and how it affects them over time.
Houston, TexasAges Up to 16 years
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Pain trials in other cities
Where these studies are running near Houston
Institutions with a site for the recruiting pain studies listed above.
- The University of Texas MD Anderson Cancer Center · 5 studies
- Baylor College of Medicine · 4 studies
- The University of Texas Health Science Center at Houston · 3 studies
- Accurate Clinical Research, Inc - Houston
- All-American Orthopedic & Sports
- Care Access
- Houston Methodist Hospital
- Juno Research LLC
What taking part in a pain study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Looking wider? See all recruiting pain studies in Texas.
Common questions
- Are there pain clinical trials near Houston?
- Yes. We're currently tracking 59 recruiting pain studies with a site near Houston, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a pain study near Houston?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Houston to take part?
- Not necessarily. These studies have a site near Houston, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a pain trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New pain studies open near Houston regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.