Clinical trials · Houston, TX
Pain clinical trials in Houston
We’re tracking 60 recruiting pain studies with a site in or near Houston — including Early Phase 1, Phase 1, Phase 1/Phase 2, Phase 2, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies near Houston
- NCT06848348RecruitingPhase 2
Halneuron for chemotherapy-induced nerve pain
This trial tests whether the drug Halneuron can safely reduce nerve pain caused by common chemotherapy drugs (platinum and taxane). It is for people whose nerve pain started after chemotherapy and whose cancer is not currently getting worse.
Houston, TexasAges 18 years+ - NCT06454669RecruitingPhase 2
Dronabinol added to opioids for chronic low back pain
This trial tests whether adding dronabinol (a prescription medication derived from cannabis) to your current opioid pain treatment can help reduce chronic low back pain more effectively. It is for people who have had persistent low back pain for at least 3 months and are already on a stable opioid regimen.
Houston, TexasAges 18–64 - NCT06827262Recruiting
A procedure for vertebrogenic back pain relief
This trial tests a minimally invasive procedure that uses a special device to target and treat nerve-related back pain coming from the vertebrae (the bones in your spine). It may offer lasting relief without more major surgery.
Houston, TexasAges 18 years+ - NCT06574269RecruitingPhase 2
Study on TLC590 for pain after surgery
This trial tests a new pain medicine, TLC590, for people having one of several common surgeries, like bunion removal, hernia repair, breast augmentation, knee replacement, or tummy tuck. The goal is to see if it helps manage pain after the procedure.
Houston, TexasAges 18–70 - NCT06602271RecruitingPhase 3
Study of PF614 for Pain After Tummy Tuck Surgery
This study tests a new painkiller called PF614 for pain after tummy tuck surgery. It compares the study drug to a placebo (a pill with no medicine) to see how well it works and how safe it is.
Houston, TexasAges 18–75 - NCT07222943Recruiting
Guided Imagery App for Kids with Stomach Pain
This study tests a mobile app that uses guided imagery (a relaxation technique using your imagination) to help children ages 7–12 with stomach pain disorders. The goal is to see if the app is easy to use and helpful for managing pain.
Houston, TexasAges 7–12 - NCT07579182RecruitingPhase 1
How Exercise and Hormones Affect Pain in Women
This study looks at how exercise affects pain and hormone levels in women. Researchers will ask you about your activity level, do some physical tests, and measure how your body responds to exercise over several visits.
Houston, TexasAges 18–60 - NCT07405645Recruiting
Focused Ultrasound for Cancer Pain in the Head or Neck
This trial tests a non-invasive focused ultrasound treatment aimed at a specific brain area to reduce severe cancer-related pain in the head, neck, or upper chest. It may help if your pain hasn't responded to standard medications.
Houston, TexasAges 18–85 - NCT07507422Recruiting
Post-market study of Inceptiv spinal cord stimulation
This study follows people receiving Inceptiv, a spinal cord stimulator from Medtronic, to see how well it works over time. It is for adults with chronic back or limb pain who have not tried spinal cord stimulation before.
Houston, TexasAges 18 years+ - NCT07016581Enrolling by invitation
Best length for a spinal cord stimulation test
This study is testing how long a spinal cord stimulation trial should last to best diagnose whether it will help your chronic pain. It compares different trial lengths to see which one gives the most accurate result.
Houston, TexasAges 18 years+ - NCT06917404RecruitingPhase 3
Knee osteoarthritis pain study: comparing a new injection to placebo
This phase 3 study tests whether a medicine called pentosan polysulfate sodium (PPS), given as a shot under the skin, reduces pain in people with knee osteoarthritis. It compares PPS to a placebo (a shot with no active medicine) to see if it is safe and effective.
Houston, TexasAges 18 years+ - NCT05991453Recruiting
Recovery after IV vs. inhaled anesthesia for non-cardiac surgery
This trial compares recovery after two types of general anesthesia: one given through an IV (propofol) and one inhaled as a gas. It aims to see which approach leads to a smoother recovery for people having non-cardiac surgery.
Houston, TexasAges 18 years+ - NCT05220202Recruiting
Program for older vets with pain and depression
This trial tests a non-medicine (non-pharmacologic) home program to help older Veterans manage musculoskeletal pain and depressive symptoms at the same time. You may be assigned to one of two approaches, and you’ll need to be able to take part from home.
Houston, TexasAges 60–99 - NCT06065449RecruitingPhase 3
Comparing two radiation therapies for painful bone metastases
This trial compares two types of radiation therapy to relieve pain from cancer that has spread to the bones. It aims to see whether a more targeted, high-dose approach (SBRT) works better than standard palliative radiation.
Houston, TexasAges 18 years+ - NCT07116109Recruiting
Brain Stimulation Plus Therapy for Pain and PTSD
This study tests whether a brain-stimulation headband (called tDCS) combined with a proven talk therapy for PTSD can help reduce both chronic pain and PTSD symptoms. It is for adults who have had chronic pain for at least 6 months and also have PTSD.
Houston, TexasAges 21 years+ - NCT07538570RecruitingPhase 4
Pain Management After Knee Replacement Surgery
This study tests different pain treatments for patients undergoing total knee replacement surgery. The goal is to find the most effective way to manage pain after this common procedure.
Houston, TexasAges 18–80 - NCT06069154Enrolling by invitation
Freezing nerves for rib fracture pain
This study tests a procedure called cryoneurolysis, which uses cold to temporarily freeze nerves near broken ribs to relieve pain. It is for adults who have 1 to 6 recently broken ribs with at least moderate pain and are already getting a nerve block injection.
Houston, TexasAges 18 years+ - NCT06744816RecruitingEarly Phase 1
Can capsaicin cream ease nerve pain after chemotherapy?
This study tests whether a capsaicin cream (made from chili peppers) can help reduce pain in the legs caused by nerve damage from past chemotherapy. It's for people who still have pain 3 months or more after finishing chemo.
Houston, TexasAges 18 years+ - NCT06354699Recruiting
Pain after surgery in children: a long-term study
This study looks at children who have certain types of surgery to understand who might have ongoing pain, what causes it, and how it affects them over time.
Houston, TexasAges Up to 16 years - NCT06381791RecruitingPhase 1/Phase 2
CBD for pain after shoulder surgery
This study tests if CBD (a cannabis extract) can help manage pain after rotator cuff repair surgery. It aims to find a better way to control pain and reduce the need for stronger painkillers.
Houston, TexasAges 18 years+ - NCT06200181RecruitingPhase 3
Olanzapine for opioid misuse in cancer pain
This study tests if a medication called olanzapine can help reduce cravings and misuse of opioid pain medicines in people with cancer pain. You would take olanzapine or a placebo daily for a few weeks while continuing your usual care.
Houston, TexasAges 18 years+ - NCT03427736Recruiting
Studying pain and numbing medicines in children
This trial looks at how well different numbing and pain-relief medicines work in children during routine care. It may help doctors choose safer, better pain control for kids who need these medicines.
Houston, TexasAges birth–17 years - NCT00515060Recruiting
Study pain testing in cancer patients and healthy volunteers
This trial uses controlled, short-term pain testing (a “pain study”) to better understand how pain works during and after certain cancer treatments. It may help researchers improve how cancer therapy pain is measured and managed.
Houston, TexasAges 18 years+ - NCT03876054Recruiting
Tracking outcomes after Abbott neurostimulator implantation
This study follows people long-term after they get an Abbott device implanted to help with chronic pain. It aims to learn how well the therapy works in real-world care over time.
Houston, TexasAges 18 years+
Hear when a new Pain trial opens near Houston, TX
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Pain trials in other cities
Where these studies are running near Houston
Institutions with a site for the recruiting pain studies listed above.
- The University of Texas MD Anderson Cancer Center · 6 studies
- Baylor College of Medicine · 3 studies
- Memorial Hermann Hospital · 2 studies
- Michael E. DeBakey VA Medical Center · 2 studies
- Central Recruiting Site
- Clinical Trial Network
- Cy-Pain and Spine
- DM Clinical Research
What taking part in a pain study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Looking wider? See all recruiting pain studies in Texas.
Common questions
- Are there pain clinical trials near Houston?
- Yes. We're currently tracking 60 recruiting pain studies with a site near Houston, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a pain study near Houston?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Houston to take part?
- Not necessarily. These studies have a site near Houston, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a pain trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New pain studies open near Houston regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.