Clinical trials · Florida
Pain clinical trials in Florida
We’re tracking 89 recruiting pain studies with a site in Florida — including Phase 1, Phase 2, Phase 2/Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies in Florida
- NCT07190807Recruiting
Optimizing spinal cord stimulation for chronic back and leg pain
This trial tests if a spinal cord stimulator with a new way of adjusting electrical settings (called independent current control) can better manage chronic pain in the back, trunk, or limbs. The goal is to find more effective sequences to reduce pain and improve daily life.
Clermont, FloridaAges 18 years+ - NCT06471075Recruiting
Mindfulness for Pain Before Orthopedic Procedure
This study tests whether a short mindfulness (calm focus) exercise before an in-clinic orthopedic procedure can help reduce pain. If you are getting kyphoplasty or radiofrequency ablation at Tallahassee Orthopedic Center, this brief program might make your experience more comfortable.
Tallahassee, FloridaAges 18 years+ - NCT07562412Recruiting
Audio Mindfulness for Quick Pain Relief
This study tests whether listening to brief guided mindfulness audio recordings can help reduce acute (sudden, short-term) pain. Researchers will see how different amounts of listening affect pain levels.
Tallahassee, FloridaAges 18 years+ - NCT07641504RecruitingPhase 2
Testing LY4065967 for chronic low back pain relief
This study tests whether a new medication called LY4065967 can reduce chronic low back pain. Researchers want to see if it works better than current treatments for people who have had lower back pain for at least 3 months.
Maitland, FloridaAges 18 years+ - NCT07587047RecruitingPhase 1
Stem cell study for chronic lower back pain
This study tests a stem cell treatment for people with ongoing lower back pain. It aims to see if the therapy can help reduce pain and improve your quality of life.
Winter Park, FloridaAges 18–85 - NCT06512727Recruiting
Pain management study for Black older adults with long-term joint pain
This study tests two different approaches to help Black adults aged 50–92 manage chronic muscle or joint pain in their hips, knees, lower back, or ankles. It aims to find which method works better to reduce pain and improve daily life.
Gainesville, FloridaAges 50–92 - NCT06224829Recruiting
Massage therapy for long-term neck pain
This study tests whether massage can help people with neck pain that has lasted at least 3 months. You will receive massage sessions, and researchers will track how your pain changes.
Gainesville, FloridaAges 18–60 - NCT07641517RecruitingPhase 2
Testing LY4065967 for chronic knee osteoarthritis pain
This study tests an experimental drug called LY4065967 to see if it can help reduce pain from osteoarthritis in the knee. You'll be in the trial for several months, with regular check-ins and pain assessments.
Maitland, FloridaAges 40 years+ - NCT07543835Recruiting
Yoga and Yoga Nidra for Chronic Low Back Pain
This study compares two types of yoga practices—traditional yoga and a deep relaxation technique called Yoga Nidra—to see which works best for chronic low back pain. You'll attend sessions over several weeks and track how your pain changes.
Orlando, FloridaAges 18–65 - NCT07392333Recruiting
Nerve ablation for chronic low back pain
This study tests a treatment that uses radiofrequency energy to target specific nerves in the spine that may be causing your low back pain. If you qualify, you would receive the OptaBlate BVN procedure and be followed over time to see how well it works.
Fort Lauderdale, FloridaAges 22 years+ - NCT07285018RecruitingPhase 2
Study of a new drug for diabetic nerve pain in legs
This trial tests an investigational drug for people with pain caused by nerve damage from diabetes (diabetic peripheral neuropathy). It may help reduce pain in your lower legs if other treatments haven't worked well.
New Port Richey, FloridaAges 18 years+ - NCT07199361Recruiting
Magnetic stimulation for chronic pain after injury or surgery
This study tests a non-invasive magnetic device placed on the skin to see how it relieves chronic pain caused by a past injury or surgery. It may help people who have had pain for at least three months and take medication for it.
Miami, FloridaAges 19–80 - NCT06827262Recruiting
A procedure for vertebrogenic back pain relief
This trial tests a minimally invasive procedure that uses a special device to target and treat nerve-related back pain coming from the vertebrae (the bones in your spine). It may offer lasting relief without more major surgery.
Orlando, FloridaAges 18 years+ - NCT06373978RecruitingPhase 4
Non-narcotic pain relief after elbow needle procedure
This study tests non-narcotic pain medicine after a needle procedure for chronic elbow tendon pain. It compares different pain-relief options to find what works best without opioids.
Coral Springs, FloridaAges 18–65 - NCT06350981Enrolling by invitationPhase 2/Phase 3
Pain control after lower back fusion surgery
This study is comparing different ways to manage pain after a specific type of lower back fusion surgery called TLIF. The goal is to find the best pain control plan to make recovery more comfortable.
Tampa, FloridaAges 18 years+ - NCT05986292RecruitingPhase 2
Study of new pain treatments for chronic pain
This study tests new treatments for people with chronic pain that has lasted at least 12 weeks. It aims to find better ways to reduce pain and improve quality of life.
Maitland, FloridaAges 18 years+ - NCT05909709RecruitingPhase 1
Tested injections for chronic facet-related back pain
This Phase 1 study tests the safety of an injection called Alocyte in adults with long-lasting back pain coming from the facet joints. If you qualify, you may be followed closely to check side effects and how you respond over multiple visits.
North Miami, FloridaAges 18 years+ - NCT05474274Enrolling by invitation
Home pain app that teaches treatment after outpatient plastic surgery
This trial tests a home-based “pain coaching” system (using a phone app and a TENS device) to help people manage pain after lower-risk outpatient plastic surgery. It may help you feel more in control of pain at home using guided exercises and device-based pain relief.
Jacksonville, FloridaAges 18 years+ - NCT04142177Recruiting
Test which pain treatments work best for chronic low back pain
This study compares how well different pain treatments reduce low back pain and improve daily life. You may be asked to start or continue care through the VA and attend in-person sessions while completing pain and activity questionnaires.
Orlando, FloridaAges 18 years+ - NCT06010251Recruiting
Body awareness therapy for spinal cord injury pain
This trial tests a multisensory approach to help people with spinal cord injury better perceive their body and reduce long-term nerve pain. It combines body awareness exercises with sensory feedback to see if it can ease pain and improve quality of life.
Miami, FloridaAges 18–70 - NCT07799857Recruiting
Light therapy for pelvic pain registry
This study tracks people getting light therapy inside the vagina for chronic pelvic pain. It helps doctors learn if this treatment works and who it helps most.
Melbourne, FloridaAges 18 years+ - NCT07632820RecruitingPhase 4
Nerve Block vs. Injection for Upper Back Muscle Pain
This study compares two ways to treat chronic muscle pain in the upper back: a nerve block (numbing injection near the spine) and trigger point injections (shots directly into painful muscle knots). The goal is to see which approach works better for long-lasting relief.
Jacksonville, FloridaAges 18–80 - NCT07415941Recruiting
Mindfulness and nerve stimulation for back pain and depression
This trial tests if combining mindfulness-based meditation with a gentle nerve stimulation device (applied to the ear) can help people aged 50–85 with chronic low back pain and depression. The goal is to reduce pain and improve mood without changing your current medications.
Tallahassee, FloridaAges 50–85 - NCT03877653Recruiting
Freedom-1 treatment for long-term knee pain in adults
This study tests a procedure called Freedom-1 to reduce long-term, limiting knee pain from knee arthritis. It may help if other non-surgical options didn’t work and you meet specific knee and health requirements.
Fort Lauderdale, FloridaAges 18 years+
Pain trials by city in Florida
Where these studies are running in Florida
Institutions with a site for the recruiting pain studies listed above.
- Accel Research Sites - DeLand Clinical Research Unit · 4 studies
- Bradenton Research Center, Inc. · 4 studies
- Charter Research · 4 studies
- Conquest Research · 4 studies
- K2 Medical Research · 4 studies
- K2 Medical Research - The Villages · 4 studies
- Merritt Island Medical Research, LLC · 4 studies
- New Horizon Research Center · 4 studies
What taking part in a pain study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Pain trials in other states
Common questions
- Are there pain clinical trials in Florida?
- Yes. We're currently tracking 89 recruiting pain studies with a site in Florida, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a pain study in Florida?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Florida to take part?
- Not necessarily. These studies have a site in Florida, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a pain trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New pain studies open in Florida regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.