Clinical trials · Maryland
Pain clinical trials in Maryland
We’re tracking 66 recruiting pain studies with a site in Maryland — including Phase 1, Phase 2 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies in Maryland
- NCT04004286Recruiting
Pain registry and blood sample biobank for eligible service members
This trial is building a pain registry biobank to learn more about pain and how different people experience it. If you’re eligible for care in the Military Healthcare System and can consent, you may be able to contribute your information for future research.
Bethesda, MarylandAges 18–80 - NCT05858996RecruitingPhase 2
Testing a pain care guideline for older adults with dementia
This trial tests a clinical guideline to improve how pain is identified and managed. It may help if you or your loved one has dementia and ongoing pain, with a focus on better pain care in nursing homes.
Baltimore, MarylandAges 60 years+ - NCT06671132RecruitingPhase 2
Computer training for pain relief using smell exercises
This trial tests a computer program that uses smell training to help people with chronic low back pain. It aims to reduce pain by retraining brain connections.
Pasadena, MarylandAges 18–85 - NCT06994988Recruiting
Smart band-aid study for chronic pain in women
This trial tests a special band-aid that measures chronic pain. Women with chronic pain or healthy women may join to help researchers learn how this device works.
Bethesda, MarylandAges 18 years+ - NCT05563038Recruiting
Scrambler therapy for pain after stroke
This trial studies whether “scrambler therapy” can reduce ongoing pain in the body areas affected by a past stroke. It may help people who are at least a month past stroke and still have stroke-related pain.
Baltimore, MarylandAges 18 years+ - NCT03258580Recruiting
Studying how culture and mind affect how we feel pain
This study looks at how beliefs, mood, and social factors affect how people express and judge pain. It mainly uses pain/heat testing and—if chosen—brain scans to understand why pain reports can differ between people.
Bethesda, MarylandAges 18–60 - NCT04142177Recruiting
Test which pain treatments work best for chronic low back pain
This study compares how well different pain treatments reduce low back pain and improve daily life. You may be asked to start or continue care through the VA and attend in-person sessions while completing pain and activity questionnaires.
Baltimore, MarylandAges 18 years+ - NCT04267588Recruiting
Using technology to track your chronic pain
This trial uses technology to follow how your pain changes over time and how it affects your daily life. It may help researchers understand pain patterns and improve pain care, as long as you can safely and consistently take part.
Baltimore, MarylandAges 21 years+ - NCT06225817Recruiting
Can a placebo help with chronic jaw pain and sleep?
This study is testing whether a placebo (a pill with no medication) can help improve sleep and reduce pain for people with long-term jaw or face pain. Researchers want to see if just expecting relief can change how your body handles pain.
Baltimore, MarylandAges 18–88 - NCT02707029Recruiting
Study of how people report pain and painful conditions
This study looks at how accurately people can describe their pain and related symptoms. It may help researchers improve how pain is measured in future studies.
Bethesda, MarylandAges 12–120 - NCT02446262Recruiting
Study of how the brain and mind shape pain in healthy adults
This study tests how people sense heat and pain, and how the brain and emotions may influence that experience. It is designed for healthy adults and may involve training sessions and (for some parts) MRI scanning.
Bethesda, MarylandAges 18–50 - NCT06383091Recruiting
Manual therapy for voice recovery after thyroid removal
This study tests if a special hands-on therapy (manual therapy) can help your voice and throat muscles recover better after total thyroidectomy. It may reduce voice problems that sometimes happen after surgery.
Baltimore, MarylandAges 18 years+ - NCT06471920Recruiting
Telerehab for chronic low back pain in rural areas
This study tests whether a video-based physical therapy program can help people with chronic low back pain who live in rural areas. If you qualify, you'll get telerehabilitation (rehab done at home through video calls) to reduce pain and improve function.
Baltimore, MarylandAges 18 years+ - NCT07231419RecruitingPhase 3
Study of suzetrigine for diabetic nerve pain
This trial tests an experimental pain drug called suzetrigine for people with diabetic peripheral neuropathy (nerve damage from diabetes that causes pain in the feet and legs). It aims to see if the drug can safely reduce pain over time.
Rockville, MarylandAges 18–80 - NCT06821607Recruiting
Telerehab for chronic low back pain
This study tests if online rehabilitation therapy can help people with ongoing low back pain. You would connect with a specialist from home.
Baltimore, MarylandAges 18–64 - NCT02821741Recruiting
Testing ear stimulation effects on pain and mood
This study tests whether stimulating the outside of your ear changes how you feel pain and how your mood/feelings are measured. It’s mainly testing a non-drug, ear-based approach and whether it affects pain signals.
Bethesda, MarylandAges 18–50 - NCT06355414RecruitingPhase 1
Psilocybin for chronic back pain and depression
This trial tests if psilocybin, a psychedelic drug, can help people with long-term low back pain who also have depression. If you qualify, you'll receive psilocybin in a controlled setting, and researchers will see how it affects your pain and mood.
Baltimore, MarylandAges 21–80 - NCT06661850Recruiting
Using Nociscan to guide discogenic low back pain surgery
This trial tests whether using a tool called Nociscan helps improve outcomes in people having surgery for low back pain caused by damaged discs. It may help doctors decide which discs need treatment.
Baltimore, MarylandAges 18–70 - NCT04996628Recruiting
Testing nerve pain signals to guide treatment for chronic pancreatitis pain
This study checks how your nerves respond to controlled touch and temperature tests, to help predict how well you’ll respond to procedures that relieve blockage in the main pancreatic duct. It may help doctors choose the most effective treatment for chronic pancreatitis pain.
Baltimore, MarylandAges 18 years+ - NCT05653778Recruiting
Nerve-stimulation treatment for painful corticobasal syndrome
This trial tests “scrambler therapy,” a type of skin-based nerve stimulation, to reduce ongoing pain from corticobasal syndrome. You may be eligible if your average pain is moderate to severe and you can safely take part in the treatment schedule.
Baltimore, MarylandAges 50–89 - NCT05666726Recruiting
Study how stress and body feelings affect choices
This study tests how changes in your internal body feelings (like heart rate and awareness of bodily sensations) and stress can affect decision-making and self-reflection. It may help researchers understand how thoughts, feelings, and body signals connect—especially in people vulnerable to anxiety or depression.
Bethesda, MarylandAges 18–55 - NCT05989230Recruiting
Emotional awareness therapy for pain after orthopedic injury
This trial tests a therapy that helps people understand and express their emotions to manage long-term pain after a serious bone injury. It may help if you have had pain most days for at least three months following surgery for an orthopedic injury.
Baltimore, MarylandAges 18 years+ - NCT06184126Recruiting
Virtual reality for sickle cell pain in the emergency room
This trial tests whether using a virtual reality (VR) headset, along with your usual pain treatment, can help reduce pain during a sickle cell crisis. It is for adults with sickle cell disease who are in the emergency department and receiving IV opioids for a vaso-occlusive crisis.
Baltimore, MarylandAges 18 years+ - NCT06204874Recruiting
Nerve stimulation for bladder pain in women
This trial tests a new nerve stimulation approach for women with bladder pain syndrome. It aims to find a gentler way to reduce pain and urgency without surgery.
Bethesda, MarylandAges 18 years+
Pain trials by city in Maryland
Where these studies are running in Maryland
Institutions with a site for the recruiting pain studies listed above.
- Johns Hopkins University · 7 studies
- National Institutes of Health Clinical Center · 5 studies
- Walter Reed National Military Medical Center · 3 studies
- Baltimore VA Medical Center
- Behavioral Medicine Research Lab
- Charles E Smilth Life Community
- Communicare Ellicott City
- communicare Marley Station
What taking part in a pain study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Pain trials in other states
Common questions
- Are there pain clinical trials in Maryland?
- Yes. We're currently tracking 66 recruiting pain studies with a site in Maryland, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a pain study in Maryland?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Maryland to take part?
- Not necessarily. These studies have a site in Maryland, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a pain trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New pain studies open in Maryland regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.