Clinical trials · Maryland
Pain clinical trials in Maryland
We’re tracking 66 recruiting pain studies with a site in Maryland — including Phase 1, Phase 1/Phase 2, Phase 2 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies in Maryland
- NCT06355414RecruitingPhase 1
Psilocybin for chronic back pain and depression
This trial tests if psilocybin, a psychedelic drug, can help people with long-term low back pain who also have depression. If you qualify, you'll receive psilocybin in a controlled setting, and researchers will see how it affects your pain and mood.
Baltimore, MarylandAges 21–80 - NCT06214923Recruiting
Virtual reality for jaw pain caused by TMD
This study tests whether immersive virtual reality can reduce chronic jaw pain from Temporomandibular Disorder (TMD). It uses EEG to see how VR affects brain activity related to pain.
Baltimore, MarylandAges 18–88 - NCT06204874Recruiting
Nerve stimulation for bladder pain in women
This trial tests a new nerve stimulation approach for women with bladder pain syndrome. It aims to find a gentler way to reduce pain and urgency without surgery.
Bethesda, MarylandAges 18 years+ - NCT06184126Recruiting
Virtual reality for sickle cell pain in the emergency room
This trial tests whether using a virtual reality (VR) headset, along with your usual pain treatment, can help reduce pain during a sickle cell crisis. It is for adults with sickle cell disease who are in the emergency department and receiving IV opioids for a vaso-occlusive crisis.
Baltimore, MarylandAges 18 years+ - NCT05989230Recruiting
Emotional awareness therapy for pain after orthopedic injury
This trial tests a therapy that helps people understand and express their emotions to manage long-term pain after a serious bone injury. It may help if you have had pain most days for at least three months following surgery for an orthopedic injury.
Baltimore, MarylandAges 18 years+ - NCT05666726Recruiting
Understanding how the body and mind influence choices
This study looks at how your body's signals and your ability to reflect on them affect the decisions you make. It involves tasks that may include mild stress, pain, food cravings, or brain scans to better understand these processes.
Bethesda, MarylandAges 18–55 - NCT05653778Recruiting
Nerve-stimulation treatment for painful corticobasal syndrome
This trial tests “scrambler therapy,” a type of skin-based nerve stimulation, to reduce ongoing pain from corticobasal syndrome. You may be eligible if your average pain is moderate to severe and you can safely take part in the treatment schedule.
Baltimore, MarylandAges 50–89 - NCT05197946Recruiting
Imaging study comparing brain changes in cerebral palsy and typical people
This study uses surveys and brain imaging (MRI) to look for patterns that match chronic pain in people with cerebral palsy, and compares them with people without cerebral palsy. It may help researchers better understand what brain features relate to chronic pain.
Baltimore, MarylandAges 8 years+ - NCT05037968Recruiting
Test bone graft materials for multi-level back fusion surgery
This trial compares two bone-graft materials to help bones heal after back fusion surgery using a rod/screw system. It may help people who have ongoing back or leg pain despite at least 3 months of non-surgical treatments.
Columbia, MarylandAges 18 years+ - NCT04996628Recruiting
Testing nerve pain signals to guide treatment for chronic pancreatitis pain
This study checks how your nerves respond to controlled touch and temperature tests, to help predict how well you’ll respond to procedures that relieve blockage in the main pancreatic duct. It may help doctors choose the most effective treatment for chronic pancreatitis pain.
Baltimore, MarylandAges 18 years+ - NCT03446456RecruitingPhase 1/Phase 2
Vasopressin and pain perception study
This trial tests whether vasopressin, a nasal spray, changes how your brain processes pain. You will receive either the spray or a placebo and have an MRI scan to see brain activity.
Baltimore, MarylandAges 18–65 - NCT00804154RecruitingPhase 1
Capsaicin-like drug for severe cancer pain
This Phase 1 trial tests a new drug related to capsaicin (resiniferatoxin) to reduce severe nerve pain from advanced cancer. It is given through a small catheter near the spinal fluid space and is meant for people whose pain medicines and other options have not worked well enough.
Bethesda, MarylandAges 18–99 - NCT05504499Recruiting
Test a new implant for low back pain with mild narrowing
This trial studies a new spine implant placed between the bones to help relieve low back pain. You may be a candidate if imaging shows mild-to-moderate spinal narrowing and you’ve already tried non-surgical treatments for at least 3 months.
Oxon Hill, MarylandAges 18 years+ - NCT05008185Recruiting
Nerve interface surgery to reduce hand pain nerve tumors
This trial tests a regenerative nerve device/surgery approach to reduce painful nerve growths (neuromas) after a finger or partial hand amputation. You may qualify if you’re an adult with confirmed, localized neuroma pain and have already tried a 6-week desensitization therapy plan.
Baltimore, MarylandAges 18 years+ - NCT04814082Recruiting
Compare two knee implant types for walking and function
This study compares two designs of knee replacement implants to see how they affect walking, function, and outcomes after surgery. You may be randomly assigned to one of the implant types used for your specific, approved knee replacement.
Baltimore, MarylandAges 18–75 - NCT06387329RecruitingPhase 4
Antibiotic to prevent UTI after bladder Botox
This study tests whether taking a low-dose antibiotic (nitrofurantoin) before a Botox bladder injection can help prevent urinary tract infections. You may be able to join if you are getting Botox for overactive bladder or painful bladder syndrome and do not have frequent UTIs or other health issues that would make the antibiotic unsafe.
Bethesda, MarylandAges 18 years+ - NCT06214949Recruiting
Personalized brain stimulation for chronic neck pain
This study tests if a personalized type of magnetic brain stimulation called PrTMS can help reduce chronic neck pain. It is for military health care beneficiaries who have had neck pain for at least 3 months.
Bethesda, MarylandAges 18–65 - NCT07317271Recruiting
Virtual reality for burn symptoms
This trial tests a virtual reality program to help with symptoms like pain, trouble sleeping, and itching after a burn injury. You can join from home using your own device.
Baltimore, MarylandAges 18 years+ - NCT06793982RecruitingPhase 4
PRP vs Corticosteroids for Hip Osteoarthritis Pain
This study compares two types of hip injections—platelet-rich plasma (PRP) and corticosteroids—to see which works better for hip osteoarthritis pain. It may help you if you are considering an injection for your hip pain.
Baltimore, MarylandAges 21–80 - NCT07174609Recruiting
Scrambler therapy for chronic pancreatitis pain
This study tests a non-invasive pain treatment called scrambler therapy for people with chronic pancreatitis. It uses mild electrical signals on the skin to try to reduce long-term belly pain.
Baltimore, MarylandAges 18 years+ - NCT07016581Enrolling by invitation
Best length for a spinal cord stimulation test
This study is testing how long a spinal cord stimulation trial should last to best diagnose whether it will help your chronic pain. It compares different trial lengths to see which one gives the most accurate result.
Baltimore, MarylandAges 18 years+ - NCT06976138Recruiting
Using Light or ions to Improve Sleep and Pain After Knee Surgery
This study tests whether a special bright light or negative ion therapy can help older adults sleep better and have less pain after knee replacement surgery. It's for people with knee arthritis who already have trouble sleeping and are scheduled for one knee replacement.
Baltimore, MarylandAges 60 years+ - NCT06884865RecruitingPhase 2
Study of an experimental knee injection for osteoarthritis pain
This study tests a new investigational medicine injected into the knee to see if it is safe and tolerable for people with painful knee osteoarthritis. It may help reduce pain and improve knee function.
Baltimore, MarylandAges 45–80 - NCT06718413RecruitingPhase 2
Study on shoulder pain after stroke
This study tests a treatment for shoulder stiffness and pain caused by muscle tightness after a stroke. It focuses on people who still have some limited shoulder movement and may help improve range of motion and comfort.
Baltimore, MarylandAges 18 years+
Pain trials by city in Maryland
Where these studies are running in Maryland
Institutions with a site for the recruiting pain studies listed above.
- Johns Hopkins University · 6 studies
- Walter Reed National Military Medical Center · 3 studies
- Luana Colloca · 2 studies
- National Institutes of Health Clinical Center · 2 studies
- Sinai Hospital of Baltimore · 2 studies
- University of Maryland · 2 studies
- F.M. Kirby Center
- Johns Hopkins Bayview Medical Center
What taking part in a pain study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Pain trials in other states
Common questions
- Are there pain clinical trials in Maryland?
- Yes. We're currently tracking 66 recruiting pain studies with a site in Maryland, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a pain study in Maryland?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Maryland to take part?
- Not necessarily. These studies have a site in Maryland, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a pain trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New pain studies open in Maryland regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.