Clinical trials
Pain clinical trials
Below are recruiting pain clinical trials, each written for real people, not researchers. We’re tracking 3,136 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06611397Recruiting
Discogen study for lower back pain with leg pain
This trial tests a treatment called Discogen for people with lower back pain that also causes leg pain. It aims to see if the treatment helps reduce pain and improve function.
New York, New YorkAges 21–75 - NCT06601218RecruitingPhase 1
Daily oral cannabis for cancer patients with solid tumors
This trial tests whether taking a daily oral cannabis (marijuana) dose is safe for people with advanced solid tumors (cancer that has spread). It's looking for people who are already on a stable cancer treatment and want to see if adding cannabis affects their symptoms or how they feel.
Lexington, KentuckyAges 18 years+ - NCT06603662RecruitingPhase 4
Steroids for sudden osteoarthritis pain in the emergency room
This trial tests if a short course of oral steroids (glucocorticoids) can relieve sudden osteoarthritis pain in the knee, hip, or shoulder for people who come to the emergency department and are well enough to go home.
York, PennsylvaniaAges 18 years+ - NCT06587607Recruiting
VR mindfulness training for veterans with spinal cord injury
This study tests whether mindfulness training with virtual reality can help veterans with spinal cord injury manage chronic pain. It is done from home using a VR headset and group video calls.
Houston, TexasAges 18 years+ - NCT06593977Recruiting
Dynavisc gel for pain after repeat carpal tunnel surgery
This trial tests a gel called Dynavisc to see if it reduces pain when placed in the wrist during a second surgery for carpal tunnel syndrome. It may help people who still have pain after their first surgery.
Leuven, BelgiumAges 18–65 - NCT06587919Enrolling by invitation
Brain training for pain after trauma
This trial tests a brain-training technique called EEG-neurofeedback to help people with ongoing pain after a traumatic event. It aims to retrain overactive brain networks to reduce pain and distress.
OdenseAges 18 years+ - NCT06574165Recruiting
Pain, mood, and brain inflammation in veterans with fibromyalgia
This study looks at how brain inflammation and mood relate to pain in veterans with fibromyalgia. It may help find new ways to treat pain by understanding these connections.
Birmingham, AlabamaAges 19–85 - NCT06583395Enrolling by invitation
Meditation retreat study with fitness tracker
This trial studies people attending a 7-day meditation retreat to see how meditation affects well-being. You will wear a fitness tracker and answer surveys.
Palm Desert, CaliforniaAges 21 years+ - NCT06568770RecruitingPhase 2/Phase 3
Comparing two nerve blocks for femur fracture surgery pain
This trial tests if one type of nerve block (PENG block) works better than another (S-FICB) for controlling pain during and after femur fracture surgery. Both blocks are guided by ultrasound to help with your recovery.
Sahiwal, Punjab ProvinceAges 20–70 - NCT06572241Recruiting
Spinal morphine for better labor pain relief
This study tests whether adding a small dose of morphine into the spinal fluid improves pain relief from an epidural during labor. If you are having your first baby and want pain relief, you may be able to take part.
Toronto, OntarioAges 18–50 - NCT06574152Recruiting
Light therapy for pain relief after dental root surgery
This trial tests whether a special light treatment, called photobiomodulation, can help reduce pain and speed up healing after a specific type of dental surgery on the root of a tooth. The surgery involves a small cut in the gum, and the light may help the gum recover faster.
Houston, TexasAges 18 years+ - NCT06580327Recruiting
Epidural Drip vs. Intermittent Doses for Women in Labor
This study compares two ways of giving epidural pain medicine during labor—continuous drip versus intermittent doses. It is for women who have given birth before and are in early labor with a single, head-down baby.
NazarethAges Any age - NCT06568406Recruiting
Early physiotherapy after episiotomy for better recovery
This study tests whether starting physiotherapy early after a childbirth-related cut (episiotomy) can help with pain, pelvic floor function, sexual health, and overall quality of life.
BrnoAges 18–40 - NCT06571006Enrolling by invitation
Music therapy for pain relief during spinal tap in babies
This study tests whether playing gentle music during a lumbar puncture (a spinal tap) can help lower a baby's pain. It's for newborn infants who need this procedure and have normal hearing.
ErzurumAges 1 month–1 month - NCT06576570Enrolling by invitation
Improving surgeon ergonomics with AI analytics
This trial uses AI to analyze surgeon posture and movements during acute care surgeries, with the goal of improving ergonomics and reducing physical strain. It may help identify better surgical practices for both surgeons and patients.
Gainesville, FloridaAges 18–99 - NCT06580561Recruiting
Exercise and insomnia treatment for knee pain
This study combines a gentle exercise program with a treatment for insomnia to see if it helps older adults with knee osteoarthritis feel less pain and sleep better. You will attend group exercise classes and receive sleep coaching.
Ann Arbor, MichiganAges 50 years+ - NCT06576830RecruitingPhase 4
Pain relief study for kids having tonsil surgery
This study tests different ways to manage pain after tonsillectomy in children. The goal is to find better pain relief options.
Durham, North CarolinaAges 3–17 - NCT05854914Recruiting
Smartphone hypnosis to reduce pain after emergency appendix surgery
This study tests whether guided hypnosis on a smartphone can lower pain after emergency surgery for a complicated appendicitis. If you qualify, you’ll use the app during your recovery and also answer quick questions about your pain and anxiety.
NiceAges 18 years+ - NCT06156384Recruiting
FITBONE nail for leg lengthening and quality of life
This study looks at pain, satisfaction, and quality of life in people who get a FITBONE lengthening nail to correct a leg length difference of more than 30mm. It will help doctors understand how well this treatment works from a patient's perspective.
Saint-Etienne, Auvergne-Rhône-AlpesAges 12 years+ - NCT05452876RecruitingPhase 2
Back care program for adults with certain spine problems
This study tests a back-care pathway (a structured plan for care) for adults with specific spine-related conditions. It aims to see whether this approach improves care for people in Alberta who may benefit from organized back treatment and guidance.
Edmonton, AlbertaAges 18 years+ - NCT06562634Enrolling by invitation
Ultrasound-guided nerve block for knee surgery pain relief
This study tests a nerve block (erector spinae plane block) to see if it reduces pain after open knee surgery. It aims to find a better way to manage pain with fewer side effects.
CairoAges 18–65 - NCT06559852Recruiting
Yoga for endometriosis pain relief study
This study tests whether a 12-week yoga program can reduce pain in women with endometriosis. It requires that your diagnosis was confirmed by surgery and that you’re not already doing yoga.
Hershey, PennsylvaniaAges 18–45 - NCT06121466RecruitingPhase 4
Belly wall injections for abdominal pain study
This study tests whether anesthetic injections into the belly wall can help relieve abdominal pain that feels like it's coming from the muscles or tissues of the belly wall itself. It may be a good option if you have localized pain and haven't tried these injections yet.
Portland, OregonAges 18–100 - NCT06538246Recruiting
Coping skills training for heart and lung failure survivors
This study tests a coping skills training program to help people who recently survived a serious heart or lung problem feel less anxious, depressed, or stressed. If you were in the ICU and now feel distressed at home, you may be able to join.
Durham, North CarolinaAges 18 years+
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Common questions
- Are there clinical trials for pain?
- Yes. Clin2 currently lists 3,136 recruiting pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.