Clinical trials
PARKINSON DISEASE (Disorder) clinical trials
Below are recruiting parkinson disease (disorder) clinical trials, each written for real people, not researchers. We’re tracking 497 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07322887RecruitingPhase 2
Study of sul-238 for early untreated parkinson's disease
This study tests whether an experimental medicine called SUL-238 can improve energy levels in the brain cells of people with early, untreated Parkinson's. It uses a special type of MRI to see if the medicine affects brain energy.
GroningenAges 40 years+ - NCT07703137Enrolling by invitation
NAD Supplement for Parkinson's Disease Study
This study tests whether a supplement called NAD (a natural substance that helps cells produce energy) can improve symptoms in people with Parkinson's disease. You would take the supplement daily for several weeks, and researchers will check your movement, thinking, and overall well-being.
Oklahoma City, OklahomaAges 55–85 - NCT07513441RecruitingPhase 1
Testing Lu AF28996 for Parkinson's disease motor fluctuations
This early-stage trial tests a new medication called Lu AF28996 in Chinese patients with Parkinson's disease who experience predictable on-off episodes (times when medication works well versus poorly). The study aims to see if this drug can help reduce those difficult off periods.
Beijing, Beijing MunicipalityAges 35–85 - NCT06449404Recruiting
7-Tesla MRI study of Parkinson's disease
This study uses a very powerful 7-Tesla MRI machine to take detailed pictures of the brain in people with Parkinson's disease. The goal is to better understand changes in the brain and possibly find new ways to track the disease.
Beijing, Beijing, ChinaAges 18–80 - NCT07174310RecruitingPhase 3
Prasinezumab for early Parkinson's disease
This study tests a new medication called prasinezumab, given through a vein (IV), to see if it can slow the progression of early-stage Parkinson's disease. It is for people who are on only one Parkinson's medication and have not yet developed motor complications.
Birmingham, AlabamaAges 50–85 - NCT04994015RecruitingTeam says not enrolling
Genetic registry for people with Parkinson’s
This study builds a genetics “registry” of people diagnosed with Parkinson’s disease who agree to genetic testing. Your information may help researchers understand why Parkinson’s happens and improve future treatments.
Birmingham, AlabamaAges 18 years+ - NCT06742450Recruiting
Comparing two ways to stimulate the brain for Parkinson's
This trial compares two methods of deep brain stimulation (constant current vs constant voltage) for people with Parkinson's who already have the device placed but haven't turned it on yet. The goal is to see which method works better.
BeijingAges 18–75 - NCT06982638Recruiting
Speeding up walking in Parkinson's with brain stimulation
This trial tests if a special type of brain stimulation (called TMS) can help people with Parkinson's disease who experience freezing of gait—when your feet feel stuck to the floor. The goal is to see if this treatment can improve walking and reduce those freezing episodes.
Charleston, South CarolinaAges 50–80 - NCT06701955Recruiting
Reliability of a Fluctuation Scale in Parkinson's
This study tests how consistently a new scale measures 'on-off' fluctuations in Parkinson's disease. If you experience motor fluctuations (times when your symptoms change) and are on stable medication, you may help validate this tool.
GrenobleAges 30–75 - NCT07100171RecruitingEarly Phase 1
GM101 injection for advanced Parkinson's disease
This trial tests an investigational gene therapy injection called GM101 for people with advanced Parkinson's disease whose symptoms are not well controlled by standard medications. The study will see if this treatment can help improve movement and quality of life.
ChangshaAges 40–70 - NCT07730073Recruiting
LSVT-LOUD therapy for voice and speech in Parkinson's disease
This study tests whether LSVT-LOUD, a speech therapy program, can improve voice, speech, and quality of life in people with Parkinson's disease who have voice or speech problems. Participants must be native Turkish speakers, aged 40-80, with mild to moderate Parkinson's.
Kâğıthane, IstanbulAges 40–80 - NCT03025334Recruiting
Brain stimulation study for thinking changes in Parkinson’s
This study tests whether a non-invasive brain stimulation approach (tDCS) can improve thinking and memory in people with Parkinson’s disease. You may be invited because your Parkinson’s is typical and your memory testing shows you do not have dementia.
Winnipeg, ManitobaAges 40 years+ - NCT05444907Recruiting
Testing treatment response in DBS-related mania in Parkinson’s
This study is looking at people with Parkinson’s who developed mania (a high-energy mood episode) after deep brain stimulation (DBS) was turned on or its settings were changed. It may help doctors better understand why this happens and how to manage it safely.
LisbonAges 18 years+ - NCT05557864Recruiting
Brain scan study for Parkinson’s patients with deep brain stimulators
This study looks at how the location of a deep brain stimulator in Parkinson’s disease affects movement problems. It mainly uses advanced 7T brain imaging to compare brain activity and motor symptoms.
Minneapolis, MinnesotaAges 21–89 - NCT05773885Recruiting
Telerehab sessions for people with Parkinson’s disease
This study tests whether rehab delivered through the internet (“telerehabilitation”) can help people with Parkinson’s disease. You may be able to do therapy from home, while the team monitors your function during the study.
Cassino, FrosinoneAges 30–80 - NCT06002581Recruiting
Using brain stimulation to slow Parkinson's disease progression
This study tests if a non-invasive brain stimulation technique called rTMS (repetitive Transcranial Magnetic Stimulation) can slow down Parkinson's disease by improving slow-wave sleep. It aims to help people with mild to moderate Parkinson's who are stable on their medication.
Shanghai, Shanghai MunicipalityAges 50–80 - NCT06028529Recruiting
Exoskeleton trial for mobility in Parkinson's
This study tests a wearable robotic exoskeleton called Keeogo to see if it can help people with Parkinson's walk better and move more easily. You would come to the Richmond VA Medical Center for visits and try walking with the device.
Richmond, VirginiaAges 18–90 - NCT06231563RecruitingPhase 2
Ketamine for depression in veterans with Parkinson's
This study tests if ketamine can help treat depression in veterans with Parkinson's disease. It involves several in-person and remote visits, and you will need to avoid certain medications and cannabis for a short time before and during some visits.
San Francisco, CaliforniaAges 40–80 - NCT06324422Recruiting
Exercise for Parkinson's fatigue
This trial tests if a structured exercise program can reduce fatigue in people with Parkinson's disease. It may help you feel less tired and improve daily function.
Aarhus, Central JutlandAges 40 years+ - NCT06530290RecruitingPhase 2
Mirtazapine for anxiety in Parkinson's disease
This trial tests whether mirtazapine, a medication often used for depression and anxiety, can reduce anxiety symptoms in people with Parkinson's disease. It is for patients with mild to moderate Parkinson's who also experience anxiety.
TehranAges 18 years+ - NCT06538298RecruitingEarly Phase 1
Exercise program with games for Parkinson's
This study tests a fun exercise program that includes games for people with Parkinson's disease. It aims to see if this type of program can help improve movement and daily life.
Ventura, CaliforniaAges 40–80 - NCT06561919Recruiting
Speech and language study during brain stimulation treatment
This is an extra part of the STIMPulseControl study that focuses on speech. It looks at how the brain stimulation treatment affects your ability to speak clearly and communicate.
CologneAges 18–70 - NCT06565195RecruitingPhase 1
Study of an experimental treatment for early Parkinson's disease
This study tests an experimental treatment (LY3962681) for people with early Parkinson's. It aims to see if the treatment is safe and can slow the disease. You must have a confirmed diagnosis, be in good overall health, and have stable medication use.
Austin, TexasAges 30–80 - NCT06087926Recruiting
TMS for apathy in Parkinson's disease
This study tests whether a non-invasive brain stimulation treatment called TMS (transcranial magnetic stimulation) can help improve apathy, or loss of motivation, in people with Parkinson's disease. You must have had symptoms for at least 4 years and be on stable Parkinson's medications.
Chapel Hill, North CarolinaAges 55–80
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Common questions
- Are there clinical trials for parkinson disease (disorder)?
- Yes. Clin2 currently lists 497 recruiting parkinson disease (disorder) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a parkinson disease (disorder) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a parkinson disease (disorder) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.