Clinical trials · Florida
Parkinson’s disease clinical trials in Florida
We’re tracking 39 recruiting parkinson’s disease studies with a site in Florida — including Phase 1, Phase 1/Phase 2, Phase 2, Phase 2/Phase 3, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies in Florida
- NCT06680830RecruitingPhase 2
Testing NEU-411 for early Parkinson's with LRRK2 gene change
This trial tests an experimental drug called NEU-411 for people with early Parkinson's disease who have a specific genetic change (LRRK2). It aims to see if the drug can slow the disease progression.
Boca Raton, FloridaAges 40–80 - NCT07026734Recruiting
Speech and Swallow Effects of Deep Brain Stimulation in Parkinson's
This study looks at how deep brain stimulation (DBS) affects speech and swallowing in people with Parkinson's disease. It aims to help understand changes so doctors can better support you after DBS surgery.
Gainesville, FloridaAges 45–85 - NCT07422675RecruitingPhase 1
Study of a new treatment for Parkinson's with motor fluctuations
This study tests a new single-dose treatment for Parkinson's disease to see if it can help reduce 'off' time—when medication wears off and symptoms return. It is for people who experience motor fluctuations and are already on a stable medication routine.
Maitland, FloridaAges 40–80 - NCT06976268RecruitingPhase 2/Phase 3
Testing BHV-8000 for early Parkinson's disease
This study tests a new once-daily pill called BHV-8000 in people who were recently diagnosed with early Parkinson's disease and are not yet on medication. The goal is to see if it can slow the progression of symptoms and improve quality of life.
Atlantis, FloridaAges 40–80 - NCT07005180RecruitingPhase 2
Carbon monoxide gas for Parkinson's disease
This trial tests if a low dose of carbon monoxide (HBI-002) is safe and helpful for people with Parkinson's disease. It requires specific health criteria and stable Parkinson's medication.
Gainesville, FloridaAges 40–80 - NCT06944522RecruitingPhase 3
Cell therapy for Parkinson's symptoms
This study tests a new cell therapy called bemdaneprocel to see if it can reduce Parkinson's symptoms and “off” time. The treatment involves transplanting special cells into the brain to help replace lost dopamine-producing cells.
Jacksonville, FloridaAges 45–75 - NCT07207122Recruiting
Focused ultrasound for Parkinson's cognitive symptoms
This trial tests whether a non-invasive ultrasound treatment, called transcranial focused ultrasound stimulation (tFUS), can improve movement and thinking in people with Parkinson's disease. It may be an option for those whose symptoms are not well controlled by medication alone.
Gainesville, FloridaAges 22–80 - NCT05266417RecruitingPhase 2
Nasal insulin plus glutathione for Parkinson’s symptoms
This Phase 2 study tests whether adding nasal insulin and glutathione can improve Parkinson’s disease symptoms and function. You would use study medicine through the nose while keeping your other treatments mostly the same during the trial.
Davie, FloridaAges 30 years+ - NCT06911229Recruiting
Walking and freezing study for Parkinson's with DBS
This study looks at how the brain controls walking and freezing of gait in people with Parkinson's disease who have deep brain stimulation (DBS). It aims to help understand why freezing happens and improve treatments.
Gainesville, FloridaAges 18–80 - NCT06719583Recruiting
Black and African Americans Connections to Parkinson's Disease
This study is building a research registry to learn more about how Parkinson's disease affects Black and African American communities. If you have Parkinson's or are a healthy volunteer, you can join by giving a saliva sample for genetic research.
Gainesville, FloridaAges 18 years+ - NCT06765668RecruitingPhase 4
Study of CREXONT for Parkinson's with wearing-off episodes
This study tests how well CREXONT, an extended-release form of carbidopa-levodopa, controls symptoms in people with Parkinson's who experience predictable 'off' periods when their regular medication wears off. The goal is to see if it can reduce the daily hours of poor mobility.
Boca Raton, FloridaAges 18 years+ - NCT06809400RecruitingPhase 1
Study of LY4006896 in healthy people and those with Parkinson's
This study tests an injectable antibody called LY4006896, first in healthy volunteers and then in people with Parkinson's disease. It aims to see if the drug is safe and how it works in the body.
The Villages, FloridaAges 30–85 - NCT07174310RecruitingPhase 3
Prasinezumab for early Parkinson's disease
This study tests a new medication called prasinezumab, given through a vein (IV), to see if it can slow the progression of early-stage Parkinson's disease. It is for people who are on only one Parkinson's medication and have not yet developed motor complications.
Atlantis, FloridaAges 50–85 - NCT04994015RecruitingTeam says not enrolling
Genetic registry for people with Parkinson’s
This study builds a genetics “registry” of people diagnosed with Parkinson’s disease who agree to genetic testing. Your information may help researchers understand why Parkinson’s happens and improve future treatments.
Aventura, FloridaAges 18 years+ - NCT06285643RecruitingPhase 2
Gene therapy for moderate Parkinson's disease
This trial tests a gene therapy (AAV2-GDNF) to see if it can slow or improve symptoms of Parkinson's disease. It is for people who have had moderate Parkinson's for 4 to 10 years and still respond to levodopa therapy.
Orlando, FloridaAges 45–75 - NCT06581523Recruiting
Breathing and meditation for Parkinson's wellness
This trial tests a breathing and meditation practice called SKY to see if it helps people with early-stage Parkinson's and their care partners feel better. You and your care partner will practice daily at home using Zoom.
Davie, FloridaAges 18–75 - NCT07432958RecruitingPhase 2
Study of AP-472 with levodopa for Parkinson's motor fluctuations
This trial tests an experimental drug called AP-472, taken alongside your regular Parkinson's medications, to see if it can reduce the amount of "OFF" time you experience each day when symptoms return between doses of levodopa.
Boca Raton, FloridaAges 30–80 - NCT07330258Recruiting
Observing Parkinson's over time in people still having movement symptoms
This study follows people with Parkinson's disease who still have movement symptoms despite taking medication. It aims to understand how the disease changes over time, which could help improve future treatments.
Miami, FloridaAges 45–75 - NCT04991831Recruiting
Registry study for Exablate thalamotomy in tremor-dominant Parkinson’s
This study follows people who are getting an Exablate procedure to treat medication-resistant, tremor-dominant Parkinson’s. It aims to track safety and outcomes in real-world care after the treatment is approved.
Miami, FloridaAges 30–99 - NCT05066763Recruiting
Surveys for people with Parkinson’s and their care partners
This trial is for people with Parkinson’s disease, their care partners, and health professionals who work with people with Parkinson’s. The Parkinson’s Foundation will contact you to collect survey information and may invite you to future research opportunities.
Miami, FloridaAges 18 years+ - NCT07674264Recruiting
Breathing therapy for thinking and movement in Parkinson's
This study tests whether a breathing-based therapy (short bursts of controlled air with higher carbon dioxide) can help with thinking and movement in people with Parkinson's disease. It may be an option for those who are not too advanced in their condition and are healthy enough to participate.
Gainesville, FloridaAges 40–75 - NCT07049341Enrolling by invitation
A pilot trial of the MemorEM device for neurological diseases
This trial tests a device called MemorEM to see how patients with neurological diseases like Alzheimer's or Parkinson's experience it. It aims to understand if the device is comfortable and easy to use.
Tampa, FloridaAges 45–100 - NCT05395624RecruitingPhase 1/Phase 2
Safety imaging study of a PET tracer in ALS, Alzheimer, MS, Parkinson
This early-phase study tests the safety of a radioactive tracer (“18F-OP-801”) and how the tracer moves through the body (biodistribution) in people with ALS, Alzheimer’s disease, multiple sclerosis, Parkinson’s disease, and in healthy volunteers. It also measures how the body processes the tracer (“pharmacokinetics”) to support future studies.
Jacksonville, FloridaAges 18–80 - NCT04373317RecruitingPhase 4
Comparing two medicines for hallucinations in Parkinson's disease
This study compares two drugs, pimavanserin and quetiapine, to see which works better for hallucinations or delusions caused by Parkinson's disease. The goal is to help patients manage these symptoms more effectively.
Gainesville, FloridaAges 40 years+
Parkinson’s disease trials by city in Florida
Where these studies are running in Florida
Institutions with a site for the recruiting parkinson’s disease studies listed above.
- University of Florida · 8 studies
- Parkinson's Disease and Movement Disorders Center of Boca Raton · 6 studies
- University of Miami · 4 studies
- University of South Florida · 4 studies
- Charter Research · 3 studies
- K2 Medical Research · 3 studies
- AdventHealth Orlando · 2 studies
- Mayo Clinic · 2 studies
What taking part in a parkinson’s disease study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Parkinson’s disease trials in other states
Common questions
- Are there parkinson’s disease clinical trials in Florida?
- Yes. We're currently tracking 39 recruiting parkinson’s disease studies with a site in Florida, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a parkinson’s disease study in Florida?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Florida to take part?
- Not necessarily. These studies have a site in Florida, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a parkinson’s disease trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New parkinson’s disease studies open in Florida regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.