Clinical trials · Ohio
Parkinson’s disease clinical trials in Ohio
We’re tracking 27 recruiting parkinson’s disease studies with a site in Ohio — including Phase 1/Phase 2, Phase 2, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies in Ohio
- NCT03019757Recruiting
Testing ways to tell dementia causes apart
This study looks at how to distinguish Alzheimer’s disease, Lewy body dementia, and Parkinson’s disease when someone has memory and thinking problems. It may help doctors choose the most accurate diagnosis and treatment path for the right condition.
Columbus, OhioAges 18 years+ - NCT06680830RecruitingPhase 2
Testing NEU-411 for early Parkinson's with LRRK2 gene change
This trial tests an experimental drug called NEU-411 for people with early Parkinson's disease who have a specific genetic change (LRRK2). It aims to see if the drug can slow the disease progression.
Columbus, OhioAges 40–80 - NCT06944522RecruitingPhase 3
Cell therapy for Parkinson's symptoms
This study tests a new cell therapy called bemdaneprocel to see if it can reduce Parkinson's symptoms and “off” time. The treatment involves transplanting special cells into the brain to help replace lost dopamine-producing cells.
Toledo, OhioAges 45–75 - NCT06719583Recruiting
Black and African Americans Connections to Parkinson's Disease
This study is building a research registry to learn more about how Parkinson's disease affects Black and African American communities. If you have Parkinson's or are a healthy volunteer, you can join by giving a saliva sample for genetic research.
Cleveland, OhioAges 18 years+ - NCT06765668RecruitingPhase 4
Study of CREXONT for Parkinson's with wearing-off episodes
This study tests how well CREXONT, an extended-release form of carbidopa-levodopa, controls symptoms in people with Parkinson's who experience predictable 'off' periods when their regular medication wears off. The goal is to see if it can reduce the daily hours of poor mobility.
Canton, OhioAges 18 years+ - NCT07110376Recruiting
Brain recordings during sleep with deep brain stimulation for Parkinson's
This study looks at brain activity during sleep in people with Parkinson's who have a deep brain stimulation (DBS) device. It aims to understand how different DBS settings affect sleep, which may help improve treatment.
Cleveland, OhioAges 18 years+ - NCT07138560RecruitingPhase 4
Study of IPX-203 for Parkinson's disease (BOOST-PD)
This study tests a new formulation of carbidopa-levodopa (IPX-203) to see how well it works for people with Parkinson's disease. It uses a wearable device to measure movement and aims to improve “off” time, when symptoms return between doses.
Cleveland, OhioAges 40 years+ - NCT07174310RecruitingPhase 3
Prasinezumab for early Parkinson's disease
This study tests a new medication called prasinezumab, given through a vein (IV), to see if it can slow the progression of early-stage Parkinson's disease. It is for people who are on only one Parkinson's medication and have not yet developed motor complications.
Canton, OhioAges 50–85 - NCT04994015RecruitingTeam says not enrolling
Genetic registry for people with Parkinson’s
This study builds a genetics “registry” of people diagnosed with Parkinson’s disease who agree to genetic testing. Your information may help researchers understand why Parkinson’s happens and improve future treatments.
Cincinnati, OhioAges 18 years+ - NCT05400499Recruiting
Deep brain stimulation study in Parkinson’s visuomotor function
This trial studies how deep brain stimulation affects hand-eye (visuomotor) coordination in people with Parkinson’s. It may help researchers understand whether the stimulation settings change movement control for daily tasks.
Cleveland, OhioAges Any age - NCT06442033Recruiting
Exercise and genetics to slow Parkinson's
This trial studies whether a regular aerobic cycling program can slow the progression of Parkinson's disease. Researchers will also look at how genetics may affect the benefits of exercise.
Cleveland, OhioAges 18 years+ - NCT06857851Recruiting
Deep brain stimulation study for movement in Parkinson's
This study looks at whether adjusting deep brain stimulation (DBS) can improve how you see and move. DBS uses a device implanted in your brain to help control Parkinson's symptoms. This research aims to find better settings for that device to improve your coordination and daily function.
Cleveland, OhioAges Any age - NCT07182058RecruitingPhase 1/Phase 2
Brain stimulation device for Parkinson's motor symptoms
This trial tests a wearable brain stimulation device (tES) that delivers gentle electrical currents to your head to help improve Parkinson's motor symptoms like tremor, stiffness, or slowness. The treatment is done at home with remote video monitoring, and may offer a non-medication option to help with movement.
Cleveland, OhioAges 18–80 - NCT06285643RecruitingPhase 2
Gene therapy for moderate Parkinson's disease
This trial tests a gene therapy (AAV2-GDNF) to see if it can slow or improve symptoms of Parkinson's disease. It is for people who have had moderate Parkinson's for 4 to 10 years and still respond to levodopa therapy.
Columbus, OhioAges 45–75 - NCT07432958RecruitingPhase 2
Study of AP-472 with levodopa for Parkinson's motor fluctuations
This trial tests an experimental drug called AP-472, taken alongside your regular Parkinson's medications, to see if it can reduce the amount of "OFF" time you experience each day when symptoms return between doses of levodopa.
Cleveland, OhioAges 30–80 - NCT07330258Recruiting
Observing Parkinson's over time in people still having movement symptoms
This study follows people with Parkinson's disease who still have movement symptoms despite taking medication. It aims to understand how the disease changes over time, which could help improve future treatments.
Cleveland, OhioAges 45–75 - NCT04991831Recruiting
Registry study for Exablate thalamotomy in tremor-dominant Parkinson’s
This study follows people who are getting an Exablate procedure to treat medication-resistant, tremor-dominant Parkinson’s. It aims to track safety and outcomes in real-world care after the treatment is approved.
Fairborn, OhioAges 30–99 - NCT07081841Enrolling by invitation
Long-term follow-up for AB-1005 study participants
This trial is for people with Parkinson's disease or multiple system atrophy (parkinsonian type) who took part in an earlier AB-1005 study. It will continue to monitor your health over time to learn more about the treatment's long-term effects.
Columbus, OhioAges Any age - NCT04373317RecruitingPhase 4
Comparing two medicines for hallucinations in Parkinson's disease
This study compares two drugs, pimavanserin and quetiapine, to see which works better for hallucinations or delusions caused by Parkinson's disease. The goal is to help patients manage these symptoms more effectively.
Cleveland, OhioAges 40 years+ - NCT04477785Recruiting
Study to track Parkinson’s signs using imaging, spinal fluid, and genes
This study is building a large, detailed group of people—some with Parkinson’s and some at higher risk—to understand early changes over time. It uses brain imaging (DaTscan SPECT), sometimes spinal fluid tests (lumbar puncture), and genetic information to help researchers better measure disease and develop future treatments.
Cincinnati, OhioAges 30 years+ - NCT01558479Recruiting
Parkinson’s genetics study for adults in affected families
This study looks at genetic (inherited) factors in Parkinson’s disease. It may help researchers better understand why Parkinson’s happens and could guide future prevention or treatments.
Cincinnati, OhioAges 18 years+ - NCT04071847Recruiting
Study tracking results after Abbott deep brain stimulator surgery
This study follows people who are getting a new Abbott deep brain stimulator (DBS) device or replacing the battery/implantable pulse generator to see how outcomes change over time. It mainly applies to certain DBS targets and diagnoses, and it uses follow-up visits to track results.
Columbus, OhioAges Any age - NCT06013956RecruitingPhase 4
Personalized deep brain stimulation for Parkinson's
This study tests a personalized way to adjust deep brain stimulation (DBS) therapy in real time for people with Parkinson's disease. It aims to improve how DBS works by tailoring it to each person's needs.
Cleveland, OhioAges 18–80 - NCT07519096Recruiting
Home-Based Fall Prevention Program for Parkinson's Disease
This study tests a fall prevention program designed for people with Parkinson's disease and their care partners. It aims to help reduce falls and improve balance and safety at home.
Beachwood, OhioAges 18 years+
Parkinson’s disease trials by city in Ohio
Where these studies are running in Ohio
Institutions with a site for the recruiting parkinson’s disease studies listed above.
- Cleveland Clinic · 10 studies
- The Ohio State University Wexner Medical Center · 5 studies
- Louis Stokes Cleveland VA Medical Center · 3 studies
- University of Cincinnati · 3 studies
- The Ohio State University · 2 studies
- University Hospitals Cleveland Medical Center · 2 studies
- Case Western Reserve University
- Cleveland Clinic (Site #223)
What taking part in a parkinson’s disease study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Parkinson’s disease trials in other states
Common questions
- Are there parkinson’s disease clinical trials in Ohio?
- Yes. We're currently tracking 27 recruiting parkinson’s disease studies with a site in Ohio, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a parkinson’s disease study in Ohio?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Ohio to take part?
- Not necessarily. These studies have a site in Ohio, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a parkinson’s disease trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New parkinson’s disease studies open in Ohio regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.