Clinical trials · California
Parkinson’s disease clinical trials in California
We’re tracking 51 recruiting parkinson’s disease studies with a site in California — including Early Phase 1, Phase 1, Phase 2, Phase 2/Phase 3, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies in California
- NCT07567794Recruiting
Gut-Brain Connection Study in Parkinson's Disease
This research examines how the gut and brain are connected in Parkinson's disease and aims to better understand the disease. You'd participate in visits and tests over three years, including some involving your digestive system.
Stanford, CaliforniaAges 21–80 - NCT04735627Recruiting
Real-time monitoring of levodopa levels in Parkinson’s
This study checks whether measuring levodopa (a Parkinson medicine) in real time can help better understand Parkinson medication effects. You may be asked to wear/perform study monitoring while taking your usual carbidopa/levodopa tablets.
San Diego, CaliforniaAges 40–85 - NCT06680830RecruitingPhase 2
Testing NEU-411 for early Parkinson's with LRRK2 gene change
This trial tests an experimental drug called NEU-411 for people with early Parkinson's disease who have a specific genetic change (LRRK2). It aims to see if the drug can slow the disease progression.
Fresno, CaliforniaAges 40–80 - NCT07554833Recruiting
Brain Stimulation for Parkinson's Motor and Memory Skills
This study tests whether repeated magnetic stimulation (rTMS) of the brain can help improve movement and thinking problems in people with Parkinson's disease. Researchers will measure how the treatment affects your motor control and cognitive function over the study period.
San Francisco, CaliforniaAges 50–90 - NCT06344026Enrolling by invitationPhase 1
A cell therapy trial for Parkinson's disease
This trial tests a new treatment made from your own cells to replace damaged brain cells, aiming to improve movement and reduce symptoms. It's for people who have had Parkinson's for at least 4 years and respond well to levodopa.
Los Angeles, CaliforniaAges 40–75 - NCT06976268RecruitingPhase 2/Phase 3
Testing BHV-8000 for early Parkinson's disease
This study tests a new once-daily pill called BHV-8000 in people who were recently diagnosed with early Parkinson's disease and are not yet on medication. The goal is to see if it can slow the progression of symptoms and improve quality of life.
Los Angeles, CaliforniaAges 40–80 - NCT07005180RecruitingPhase 2
Carbon monoxide gas for Parkinson's disease
This trial tests if a low dose of carbon monoxide (HBI-002) is safe and helpful for people with Parkinson's disease. It requires specific health criteria and stable Parkinson's medication.
Fountain Valley, CaliforniaAges 40–80 - NCT06944522RecruitingPhase 3
Cell therapy for Parkinson's symptoms
This study tests a new cell therapy called bemdaneprocel to see if it can reduce Parkinson's symptoms and “off” time. The treatment involves transplanting special cells into the brain to help replace lost dopamine-producing cells.
Los Angeles, CaliforniaAges 45–75 - NCT07207122Recruiting
Focused ultrasound for Parkinson's cognitive symptoms
This trial tests whether a non-invasive ultrasound treatment, called transcranial focused ultrasound stimulation (tFUS), can improve movement and thinking in people with Parkinson's disease. It may be an option for those whose symptoms are not well controlled by medication alone.
Santa Monica, CaliforniaAges 22–80 - NCT04650932Recruiting
Study tests new stimulation settings for advanced Parkinson’s
This study looks at whether changing how deep brain stimulation (DBS) pulses are delivered can improve symptoms in people with advanced Parkinson’s disease. You may be eligible if you already have a specific Boston Scientific DBS device and have had it implanted for at least 3 months.
Sacramento, CaliforniaAges 18 years+ - NCT06455293RecruitingPhase 2
Psilocybin therapy for depression in Parkinson's disease
This study tests whether psilocybin, a substance found in certain mushrooms, can help improve depression in people with Parkinson's disease. If you have Parkinson's and are feeling depressed, this treatment may offer a new option.
San Francisco, CaliforniaAges 40–80 - NCT06765668RecruitingPhase 4
Study of CREXONT for Parkinson's with wearing-off episodes
This study tests how well CREXONT, an extended-release form of carbidopa-levodopa, controls symptoms in people with Parkinson's who experience predictable 'off' periods when their regular medication wears off. The goal is to see if it can reduce the daily hours of poor mobility.
Palo Alto, CaliforniaAges 18 years+ - NCT06809400RecruitingPhase 1
Study of LY4006896 in healthy people and those with Parkinson's
This study tests an injectable antibody called LY4006896, first in healthy volunteers and then in people with Parkinson's disease. It aims to see if the drug is safe and how it works in the body.
Los Alamitos, CaliforniaAges 30–85 - NCT07284823Recruiting
Cionic sleeve study for walking problems in Parkinson's
This trial tests a wearable sleeve that uses gentle electrical signals to help improve walking in people with Parkinson's disease. It aims to see if the sleeve is safe and easy to use.
San Francisco, CaliforniaAges 22–75 - NCT06819020Enrolling by invitation
Adaptive deep brain stimulation for freezing of gait in Parkinson's
This trial tests an adaptive deep brain stimulation (DBS) system designed to improve freezing of gait in Parkinson’s disease. It is for people who still have trouble walking despite medications and are already planning to have DBS surgery.
San Francisco, CaliforniaAges 21–75 - NCT05779475Enrolling by invitation
Study of people with moderate Parkinson’s disease
This is an observational study, meaning it doesn’t test a new drug—researchers mainly follow people to better understand moderate Parkinson’s disease and who may be good candidates for future cell therapy. If you have moderate symptoms that aren’t well controlled with tablets, this study may help inform better future treatments.
Irvine, CaliforniaAges 50–68 - NCT05504902Enrolling by invitation
Device training for advanced Parkinson’s using touch feedback
This study tests whether coordinated touch (vibrotactile) training can improve symptoms in people with Parkinson’s. You may be asked to use a special device and attend virtual check-ins, with some visits requiring stopping Parkinson’s meds for short periods.
Stanford, CaliforniaAges 18 years+ - NCT05166655Enrolling by invitation
Recording brain signals during deep brain stimulation for Parkinson’s
This study uses special recordings during deep brain stimulation surgery to better understand how movement gets easier in Parkinson’s disease. It may help researchers improve how this therapy is used for advanced symptoms.
Los Angeles, CaliforniaAges 18 years+ - NCT07174310RecruitingPhase 3
Prasinezumab for early Parkinson's disease
This study tests a new medication called prasinezumab, given through a vein (IV), to see if it can slow the progression of early-stage Parkinson's disease. It is for people who are on only one Parkinson's medication and have not yet developed motor complications.
Fullerton, CaliforniaAges 50–85 - NCT04994015RecruitingTeam says not enrolling
Genetic registry for people with Parkinson’s
This study builds a genetics “registry” of people diagnosed with Parkinson’s disease who agree to genetic testing. Your information may help researchers understand why Parkinson’s happens and improve future treatments.
La Jolla, CaliforniaAges 18 years+ - NCT05968703Recruiting
Deep brain stimulation study for mild memory trouble in Parkinson’s
This trial looks at a specific type of deep brain stimulation (DBS) to see if it can help people with Parkinson’s who have mild cognitive problems (mild memory/thinking changes). You may also be asked to temporarily stop Parkinson’s medications around research visits to measure effects more clearly.
Stanford, CaliforniaAges 21–80 - NCT06231563RecruitingPhase 2
Ketamine for depression in veterans with Parkinson's
This study tests if ketamine can help treat depression in veterans with Parkinson's disease. It involves several in-person and remote visits, and you will need to avoid certain medications and cannabis for a short time before and during some visits.
San Francisco, CaliforniaAges 40–80 - NCT06538298RecruitingEarly Phase 1
Exercise program with games for Parkinson's
This study tests a fun exercise program that includes games for people with Parkinson's disease. It aims to see if this type of program can help improve movement and daily life.
Ventura, CaliforniaAges 40–80 - NCT07398157Recruiting
24-hour adaptive deep brain stimulation for Parkinson's
This trial tests a new deep brain stimulation system that adapts in real time to improve symptom control over 24 hours, especially for people with daytime fluctuations or sleep problems despite standard DBS.
San Francisco, CaliforniaAges 18 years+
Parkinson’s disease trials by city in California
Where these studies are running in California
Institutions with a site for the recruiting parkinson’s disease studies listed above.
- University of California, Los Angeles (UCLA) · 6 studies
- University of California, San Francisco · 6 studies
- Parkinson's Research Centers of America · 3 studies
- Stanford Neuroscience Health Center · 3 studies
- Stanford University · 2 studies
- University of California San Diego · 2 studies
- University of California San Diego Health · 2 studies
- University of California, Irvine Medical Center / UC Irvine Health · 2 studies
What taking part in a parkinson’s disease study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Parkinson’s disease trials in other states
Common questions
- Are there parkinson’s disease clinical trials in California?
- Yes. We're currently tracking 51 recruiting parkinson’s disease studies with a site in California, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a parkinson’s disease study in California?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in California to take part?
- Not necessarily. These studies have a site in California, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a parkinson’s disease trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New parkinson’s disease studies open in California regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.